Riboswitches. A riboswitch-containing sRNA controls gene expression by sequestration of a response regulator.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMC 4356242)

Published in Science on August 22, 2014

Authors

Sruti DebRoy1, Margo Gebbie2, Arati Ramesh3, Jonathan R Goodson2, Melissa R Cruz1, Ambro van Hoof1, Wade C Winkler4, Danielle A Garsin5

Author Affiliations

1: Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, TX 77030, USA.
2: Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
3: Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
4: Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA. danielle.a.garsin@uth.tmc.edu wwinkler@umd.edu.
5: Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, TX 77030, USA. danielle.a.garsin@uth.tmc.edu wwinkler@umd.edu.

Articles citing this

What a Dinner Party! Mechanisms and Functions of Interkingdom Signaling in Host-Pathogen Associations. MBio (2016) 0.85

Transcriptional analysis of Deinococcus radiodurans reveals novel small RNAs that are differentially expressed under ionizing radiation. Appl Environ Microbiol (2014) 0.85

RNA systems biology: uniting functional discoveries and structural tools to understand global roles of RNAs. Curr Opin Biotechnol (2016) 0.80

Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains. Nat Struct Mol Biol (2015) 0.80

Genome-wide analyses of small non-coding RNAs in streptococci. Front Genet (2015) 0.78

Small RNA Transcriptome of the Oral Microbiome during Periodontitis Progression. Appl Environ Microbiol (2015) 0.77

Identification and Characterization of Novel Small RNAs in Rickettsia prowazekii. Front Microbiol (2016) 0.76

RNA. Riboswitch regulates RNA. Science (2014) 0.76

Linking aptamer-ligand binding and expression platform folding in riboswitches: prospects for mechanistic modeling and design. Wiley Interdiscip Rev RNA (2015) 0.76

Rapid RNA-ligand interaction analysis through high-information content conformational and stability landscapes. Nat Commun (2015) 0.76

The unmasking of 'junk' RNA reveals novel sRNAs: from processed RNA fragments to marooned riboswitches. Curr Opin Microbiol (2016) 0.75

Deciphering the Transcriptional Response Mediated by the Redox-Sensing System HbpS-SenS-SenR from Streptomycetes. PLoS One (2016) 0.75

Functional studies of E. faecalis RNase J2 and its role in virulence and fitness. PLoS One (2017) 0.75

The Mechanisms of Virulence Regulation by Small Noncoding RNAs in Low GC Gram-Positive Pathogens. Int J Mol Sci (2015) 0.75

Discrimination and Integration of Stress Signals by Pathogenic Bacteria. Cell Host Microbe (2016) 0.75

Cobalamin Riboswitches Exhibit a Broad Range of Ability to Discriminate between Methylcobalamin and Adenosylcobalamin. J Biol Chem (2017) 0.75

Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation. Nucleic Acids Res (2017) 0.75

Articles cited by this

Regulatory RNAs in bacteria. Cell (2009) 9.57

The structural and functional diversity of metabolite-binding riboswitches. Annu Rev Biochem (2009) 4.20

A decade of riboswitches. Cell (2013) 3.26

CsrB sRNA family: sequestration of RNA-binding regulatory proteins. Curr Opin Microbiol (2007) 2.83

A trans-acting riboswitch controls expression of the virulence regulator PrfA in Listeria monocytogenes. Cell (2009) 2.62

Ethanolamine utilization in bacterial pathogens: roles and regulation. Nat Rev Microbiol (2010) 2.02

Microbial metabolism of amino alcohols. Ethanolamine catabolism mediated by coenzyme B12-dependent ethanolamine ammonia-lyase in Escherichia coli and Klebsiella aerogenes. J Gen Microbiol (1976) 1.90

Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions. Proc Natl Acad Sci U S A (2011) 1.58

B12 cofactors directly stabilize an mRNA regulatory switch. Nature (2012) 1.38

Multiple posttranscriptional regulatory mechanisms partner to control ethanolamine utilization in Enterococcus faecalis. Proc Natl Acad Sci U S A (2009) 1.38

Structural insights into ligand binding and gene expression control by an adenosylcobalamin riboswitch. Nat Struct Mol Biol (2012) 1.30

Ethanolamine activates a sensor histidine kinase regulating its utilization in Enterococcus faecalis. J Bacteriol (2008) 1.21

The mechanism for RNA recognition by ANTAR regulators of gene expression. PLoS Genet (2012) 1.00

Transcription antitermination by a phosphorylated response regulator and cobalamin-dependent termination at a B₁₂ riboswitch contribute to ethanolamine utilization in Enterococcus faecalis. J Bacteriol (2011) 0.94