Published in Nat Immunol on August 24, 2014
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell (2014) 3.52
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature (2014) 2.91
C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. Immunity (2015) 2.29
Macrophages and therapeutic resistance in cancer. Cancer Cell (2015) 1.95
Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth. Nat Immunol (2015) 1.67
Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms. Mediators Inflamm (2015) 1.48
Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors. J Leukoc Biol (2015) 1.44
The interaction of anticancer therapies with tumor-associated macrophages. J Exp Med (2015) 1.44
T-Cell Depletion in the Colonic Mucosa of Patients With Idiopathic CD4+ Lymphopenia. J Infect Dis (2015) 1.41
Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs. Science (2015) 1.35
New insights into the multidimensional concept of macrophage ontogeny, activation and function. Nat Immunol (2015) 1.31
Regulation of macrophage development and function in peripheral tissues. Nat Rev Immunol (2015) 1.16
The development and maintenance of resident macrophages. Nat Immunol (2015) 1.13
Tissue-resident macrophages: then and now. Immunology (2015) 1.10
Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages. J Clin Invest (2015) 1.07
Monocyte trafficking across the vessel wall. Cardiovasc Res (2015) 1.06
Guardians of the Gut - Murine Intestinal Macrophages and Dendritic Cells. Front Immunol (2015) 1.06
The microbiome and innate immunity. Nature (2016) 1.05
The pancreas anatomy conditions the origin and properties of resident macrophages. J Exp Med (2015) 1.04
The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis. Nat Immunol (2015) 1.03
Monocytes in myocardial infarction. Arterioscler Thromb Vasc Biol (2015) 1.03
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells. Nat Commun (2016) 1.03
Targeting GM-CSF in inflammatory diseases. Nat Rev Rheumatol (2015) 0.97
Human and Mouse Mononuclear Phagocyte Networks: A Tale of Two Species? Front Immunol (2015) 0.95
Myocardial infarction: a critical role of macrophages in cardiac remodeling. Front Physiol (2015) 0.94
The Interplay Between Monocytes/Macrophages and CD4(+) T Cell Subsets in Rheumatoid Arthritis. Front Immunol (2015) 0.92
Ontogeny of Tissue-Resident Macrophages. Front Immunol (2015) 0.91
Macrophage heterogeneity in the context of rheumatoid arthritis. Nat Rev Rheumatol (2016) 0.91
The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD. Nat Rev Gastroenterol Hepatol (2015) 0.90
Beyond vascular inflammation--recent advances in understanding atherosclerosis. Cell Mol Life Sci (2015) 0.90
Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities. Nat Commun (2016) 0.89
Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis. Blood (2016) 0.89
Defining Mononuclear Phagocyte Subset Homology Across Several Distant Warm-Blooded Vertebrates Through Comparative Transcriptomics. Front Immunol (2015) 0.89
Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation. Front Immunol (2015) 0.88
CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation. Immunity (2016) 0.88
Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes. Nat Commun (2015) 0.88
Colonic macrophage polarization in homeostasis, inflammation, and cancer. Am J Physiol Gastrointest Liver Physiol (2016) 0.87
New Insights Into Tissue Macrophages: From Their Origin to the Development of Memory. Immune Netw (2015) 0.85
A Hitchhiker's Guide to Myeloid Cell Subsets: Practical Implementation of a Novel Mononuclear Phagocyte Classification System. Front Immunol (2015) 0.85
Monocyte differentiation and antigen-presenting functions. Nat Rev Immunol (2017) 0.84
Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation. EMBO J (2016) 0.83
CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23. Mucosal Immunol (2015) 0.83
Intestinal Monocyte-Derived Macrophages Control Commensal-Specific Th17 Responses. Cell Rep (2015) 0.83
Effects of dyslipidaemia on monocyte production and function in cardiovascular disease. Nat Rev Cardiol (2017) 0.81
Development and Function of Arterial and Cardiac Macrophages. Trends Immunol (2016) 0.81
Tumor macrophages are pivotal constructors of tumor collagenous matrix. J Exp Med (2016) 0.81
Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes. Cell Rep (2015) 0.80
Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells. J Immunol Res (2016) 0.80
Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD. J Lipid Res (2016) 0.80
Intrinsic Gastrointestinal Macrophages: Their Phenotype and Role in Gastrointestinal Motility. Cell Mol Gastroenterol Hepatol (2016) 0.79
Differential roles of resident microglia and infiltrating monocytes in murine CNS autoimmunity. Semin Immunopathol (2015) 0.79
Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation. J Crohns Colitis (2016) 0.78
Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis. Pediatr Res (2016) 0.78
Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation. Am J Physiol Gastrointest Liver Physiol (2015) 0.78
Do not judge a cell by its cover-diversity of CNS resident, adjoining and infiltrating myeloid cells in inflammation. Semin Immunopathol (2015) 0.78
Macrophage-based cell therapies: The long and winding road. J Control Release (2016) 0.78
Does niche competition determine the origin of tissue-resident macrophages? Nat Rev Immunol (2017) 0.78
Human Induced Pluripotent Stem Cell-Derived Macrophages Share Ontogeny with MYB-Independent Tissue-Resident Macrophages. Stem Cell Reports (2017) 0.77
Neonatal mucosal immunology. Mucosal Immunol (2016) 0.77
Controlling the cytokine storm in severe bacterial diarrhoea with an oral Toll-like receptor 4 antagonist. Immunology (2015) 0.77
Ontogeny of Tumor-associated Macrophages and Its Implication in Cancer Regulation. Trends Cancer (2016) 0.77
SLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine. Gastroenterology (2015) 0.77
Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells. J Exp Med (2016) 0.77
Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells. Oncotarget (2016) 0.77
Early hematopoiesis and macrophage development. Semin Immunol (2016) 0.77
Transcriptional Regulation of Mononuclear Phagocyte Development. Front Immunol (2015) 0.77
Homeostatic Immunity and the Microbiota. Immunity (2017) 0.77
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis. Mol Ther (2017) 0.76
Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling. Mucosal Immunol (2017) 0.76
The Role of the Microbiota in Shaping Infectious Immunity. Trends Immunol (2016) 0.76
Diversity of Intestinal Macrophages in Inflammatory Bowel Diseases. Front Immunol (2015) 0.76
Development and function of tissue resident macrophages in mice. Semin Immunol (2016) 0.76
Neuron-macrophage crosstalk in the intestine: a "microglia" perspective. Front Cell Neurosci (2015) 0.76
Myeloid Cell Turnover and Clearance. Microbiol Spectr (2016) 0.76
The pattern of GPI-80 expression is a useful marker for unusual myeloid maturation in peripheral blood. Clin Exp Immunol (2016) 0.76
Neutralization of pro-inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis. EMBO J (2016) 0.76
Intestinal Antigen-Presenting Cells: Key Regulators of Immune Homeostasis and Inflammation. Am J Pathol (2015) 0.76
Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity. Mucosal Immunol (2015) 0.76
β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon. Mucosal Immunol (2015) 0.76
The fate and lifespan of human monocyte subsets in steady state and systemic inflammation. J Exp Med (2017) 0.75
Macrophage heterogeneity and renin-angiotensin system disorders. Pflugers Arch (2017) 0.75
Microvasculature remodeling in the mouse lower gut during inflammaging. Sci Rep (2017) 0.75
The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis. Immunol Cell Biol (2016) 0.75
Antigen Presentation in Transplantation. Trends Immunol (2016) 0.75
Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis. Sci Rep (2016) 0.75
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine. Sci Rep (2016) 0.75
Immunological profiling of patients with ulcerative colitis leads to identification of two inflammatory conditions and CD1a as a disease marker. J Transl Med (2016) 0.75
Relationship between Immunological Abnormalities in Rat Models of Diabetes Mellitus and the Amplification Circuits for Diabetes. J Diabetes Res (2017) 0.75
Maturation Phenotype of Peripheral Blood Monocyte/Macrophage After Stimulation with Lipopolysaccharides in Irritable Bowel Syndrome. J Neurogastroenterol Motil (2017) 0.75
L13a-dependent translational control in macrophages limits the pathogenesis of colitis. Cell Mol Immunol (2015) 0.75
Macrophages and dendritic cells in the post-testicular environment. Cell Tissue Res (2015) 0.75
Diversity and functions of intestinal mononuclear phagocytes. Mucosal Immunol (2017) 0.75
JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages. J Immunol (2016) 0.75
Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases. Clin Transl Immunology (2016) 0.75
Islet inflammation in type 2 diabetes and physiology. J Clin Invest (2017) 0.75
Macrophages in gastrointestinal homeostasis and inflammation. Pflugers Arch (2017) 0.75
Bone marrow-derived macrophages distinct from tissue-resident macrophages play a pivotal role in Concanavalin A-induced murine liver injury via CCR9 axis. Sci Rep (2016) 0.75
A Critical Role for Monocytes/Macrophages During Intestinal Inflammation-associated Lymphangiogenesis. Inflamm Bowel Dis (2016) 0.75
Tissue adaptation: Implications for gut immunity and tolerance. J Exp Med (2017) 0.75
Tissue-resident macrophages - how to humanize our knowledge. Immunol Cell Biol (2016) 0.75
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol (2000) 14.74
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol (2006) 11.06
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature (2011) 8.62
A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science (2012) 8.42
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J Clin Invest (1997) 7.58
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci (2007) 7.42
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci (2007) 6.23
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity (2012) 6.18
Origin of the lamina propria dendritic cell network. Immunity (2009) 5.95
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity (2013) 5.47
Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity (2009) 5.43
Origin of dendritic cells in peripheral lymphoid organs of mice. Nat Immunol (2007) 5.31
The origin and development of nonlymphoid tissue CD103+ DCs. J Exp Med (2009) 4.79
Haematopoietic stem cells derive directly from aortic endothelium during development. Nature (2010) 4.42
The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells. Bull World Health Organ (1972) 4.25
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci (2011) 4.21
Tissue-resident macrophages. Nat Immunol (2013) 4.09
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity (2014) 3.54
Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasis. Mucosal Immunol (2009) 3.52
Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One (2010) 3.24
Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon. J Exp Med (2012) 3.20
Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80. J Exp Med (1985) 3.11
Kinetics of central nervous system microglial and macrophage engraftment: analysis using a transgenic bone marrow transplantation model. Blood (1997) 2.87
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. J Exp Med (2009) 2.77
Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunol (2012) 2.73
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med (2012) 2.69
Origin and functions of tissue macrophages. Immunity (2014) 2.63
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 2.61
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J Exp Med (2013) 2.47
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis. Eur J Immunol (2012) 2.27
Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity (2013) 2.20
Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions. J Immunol (2010) 2.06
A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation. Eur J Immunol (2011) 1.70
An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation. J Immunol (2010) 1.65
Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells. J Leukoc Biol (2006) 1.47
Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes. Cell Host Microbe (2012) 1.26
Direct evidence of monocyte recruitment to inflammatory bowel disease mucosa. J Gastroenterol Hepatol (1996) 1.23
Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10. Int Immunol (2010) 1.21
Multicolor fate mapping of Langerhans cell homeostasis. J Exp Med (2013) 1.06
CD200 receptor and macrophage function in the intestine. Immunobiology (2011) 1.01
Lamina propria macrophages in the human gastrointestinal mucosa: their distribution, immunohistological phenotype, and function. J Histochem Cytochem (1996) 1.00
The monocyte-macrophage axis in the intestine. Cell Immunol (2014) 0.97