Published in Mol Cell on August 21, 2014
Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature (2016) 3.05
Systematic discovery of Xist RNA binding proteins. Cell (2015) 2.26
Long Noncoding RNAs in Cancer Pathways. Cancer Cell (2016) 1.63
Neat1 is a p53-inducible lincRNA essential for transformation suppression. Genes Dev (2017) 1.39
GRID-seq reveals the global RNA-chromatin interactome. Nat Biotechnol (2017) 1.38
Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma. J Exp Clin Cancer Res (2015) 1.36
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes Dev (2015) 1.27
LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. Oncotarget (2015) 1.12
Long noncoding RNAs: Re-writing dogmas of RNA processing and stability. Biochim Biophys Acta (2015) 1.08
Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus. Genes Dev (2015) 0.97
The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation. Nucleic Acids Res (2015) 0.95
Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer. Oncotarget (2016) 0.92
Long non-coding RNAs in cancer and development: where do we go from here? Int J Mol Sci (2015) 0.92
Nuclear-enriched abundant transcript 1 as a diagnostic and prognostic biomarker in colorectal cancer. Mol Cancer (2015) 0.91
Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression. Nat Rev Mol Cell Biol (2016) 0.91
A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation. Cell (2016) 0.91
MALAT1 is an oncogenic long non-coding RNA associated with tumor invasion in non-small cell lung cancer regulated by DNA methylation. Int J Clin Exp Pathol (2015) 0.88
Dissecting the nascent human transcriptome by analysing the RNA content of transcription factories. Nucleic Acids Res (2015) 0.86
Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization. J Cell Biol (2016) 0.84
Discovery and Classification of Fusion Transcripts in Prostate Cancer and Normal Prostate Tissue. Am J Pathol (2015) 0.83
MicroRNA 140 Promotes Expression of Long Noncoding RNA NEAT1 in Adipogenesis. Mol Cell Biol (2015) 0.82
Enhanced expression of long non-coding RNA NEAT1 is associated with the progression of gastric adenocarcinomas. World J Surg Oncol (2016) 0.82
Long non-coding RNA regulation of reproduction and development. Mol Reprod Dev (2015) 0.82
Advances in the characterization of RNA-binding proteins. Wiley Interdiscip Rev RNA (2016) 0.81
Chromatin and extracellular vesicle associated sperm RNAs. Nucleic Acids Res (2015) 0.81
Constructing 3D interaction maps from 1D epigenomes. Nat Commun (2016) 0.81
MALAT1 and HOTAIR Long Non-Coding RNAs Play Opposite Role in Estrogen-Mediated Transcriptional Regulation in Prostate Cancer Cells. Sci Rep (2016) 0.80
RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery. Nucleic Acids Res (2016) 0.80
The non-coding RNA composition of the mitotic chromosome by 5'-tag sequencing. Nucleic Acids Res (2016) 0.79
Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction. Epigenomics (2015) 0.79
Unveiling the hidden function of long non-coding RNA by identifying its major partner-protein. Cell Biosci (2015) 0.79
Epigenetics in the Vascular Endothelium: Looking From a Different Perspective in the Epigenomics Era. Arterioscler Thromb Vasc Biol (2015) 0.79
Nascent Connections: R-Loops and Chromatin Patterning. Trends Genet (2016) 0.78
Circadian RNA expression elicited by 3'-UTR IRAlu-paraspeckle associated elements. Elife (2016) 0.78
Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions. Nat Commun (2016) 0.78
HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2. Sci Rep (2016) 0.78
NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing. Nat Struct Mol Biol (2017) 0.77
The Sam68 nuclear body is composed of two RNase-sensitive substructures joined by the adaptor HNRNPL. J Cell Biol (2016) 0.77
LncRNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate Shp mRNA decay. Hepatology (2016) 0.77
The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection. Sci Rep (2015) 0.77
Chromatin remodeling complexes in the assembly of long noncoding RNA-dependent nuclear bodies. Nucleus (2015) 0.77
LncRNAs in vertebrates: advances and challenges. Biochimie (2015) 0.77
A Comprehensive Characterization of the Function of LincRNAs in Transcriptional Regulation Through Long-Range Chromatin Interactions. Sci Rep (2016) 0.76
Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice. PLoS One (2016) 0.76
Specific RNP capture with antisense LNA/DNA mixmers. RNA (2017) 0.76
Inverted repeat Alu elements in the human lincRNA-p21 adopt a conserved secondary structure that regulates RNA function. Nucleic Acids Res (2016) 0.75
Analysis of hypoxia-induced noncoding RNAs reveals metastasis-associated lung adenocarcinoma transcript 1 as an important regulator of vascular smooth muscle cell proliferation. Exp Biol Med (Maywood) (2017) 0.75
Malat1 regulates myogenic differentiation and muscle regeneration through modulating MyoD transcriptional activity. Cell Discov (2017) 0.75
Long Noncoding RNA MALAT1 Promotes Hepatocellular Carcinoma Development by SRSF1 Upregulation and mTOR Activation. Cancer Res (2016) 0.75
Nono, a Bivalent Domain Factor, Regulates Erk Signaling and Mouse Embryonic Stem Cell Pluripotency. Cell Rep (2016) 0.75
Systematic Mapping of RNA-Chromatin Interactions In Vivo. Curr Biol (2017) 0.75
LncRNA: a versatile regulator of the NF-κB signaling circuit. Immunology (2016) 0.75
Unusual semi-extractability as a hallmark of nuclear body-associated architectural noncoding RNAs. EMBO J (2017) 0.75
Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order Structures. Int J Mol Sci (2016) 0.75
NEAT1 modulates herpes simplex virus-1 replication by regulating viral gene transcription. Cell Mol Life Sci (2016) 0.75
Long non-coding RNA MALAT-1 modulates metastatic potential of tongue squamous cell carcinomas partially through the regulation of small proline rich proteins. BMC Cancer (2016) 0.75
Insight into lncRNA biology using hybridization capture analyses. Biochim Biophys Acta (2015) 0.75
The Association between Abnormal Long Noncoding RNA MALAT-1 Expression and Cancer Lymph Node Metastasis: A Meta-Analysis. Biomed Res Int (2016) 0.75
Shedding light on paraspeckle structure by super-resolution microscopy. J Cell Biol (2016) 0.75
Identification and characterization of a long non-coding RNA up-regulated during HIV-1 infection. Virology (2017) 0.75
Cellular, physiological and pathological aspects of the long non-coding RNA NEAT1. Front Biol (Beijing) (2016) 0.75
Short-lived long non-coding RNAs as surrogate indicators for chemical exposure and LINC00152 and MALAT1 modulate their neighboring genes. PLoS One (2017) 0.75
A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression. Nat Cell Biol (2017) 0.75
Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
The ENCODE (ENCyclopedia Of DNA Elements) Project. Science (2004) 38.24
Long non-coding RNAs: insights into functions. Nat Rev Genet (2009) 19.61
A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol (2011) 16.53
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res (2012) 15.41
Long noncoding RNA as modular scaffold of histone modification complexes. Science (2010) 15.23
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software. Bioinformatics (2011) 12.98
Design and analysis of ChIP-seq experiments for DNA-binding proteins. Nat Biotechnol (2008) 10.10
CLIP identifies Nova-regulated RNA networks in the brain. Science (2003) 8.88
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene (2003) 7.90
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol Cell (2011) 6.83
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics (2007) 6.28
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell (2009) 6.08
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell (2011) 5.65
Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo. J Biol Chem (2001) 5.36
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43. Nat Neurosci (2011) 5.24
A high-resolution map of the three-dimensional chromatin interactome in human cells. Nature (2013) 5.18
MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res (2008) 5.06
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell (2009) 5.03
The dynamics of a pre-mRNA splicing factor in living cells. Nature (1997) 4.97
A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell (2011) 4.42
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell (2011) 4.26
Paraspeckles: a novel nuclear domain. Curr Biol (2002) 4.19
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science (2013) 4.12
Complex Loci in human and mouse genomes. PLoS Genet (2006) 3.74
MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles. Proc Natl Acad Sci U S A (2009) 3.63
Purification of proteins associated with specific genomic Loci. Cell (2009) 3.53
Flavopiridol inhibits P-TEFb and blocks HIV-1 replication. J Biol Chem (2000) 3.13
Nuclear speckles. Cold Spring Harb Perspect Biol (2011) 3.04
Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells. Genome Biol (2004) 2.77
Biogenesis and function of nuclear bodies. Trends Genet (2011) 2.60
Genome-wide analysis of long noncoding RNA stability. Genome Res (2012) 2.49
Understanding the transcriptome through RNA structure. Nat Rev Genet (2011) 2.46
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Rep (2012) 2.45
The genomic binding sites of a noncoding RNA. Proc Natl Acad Sci U S A (2011) 2.34
Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity. EMBO J (1997) 2.27
Processing of endogenous pre-mRNAs in association with SC-35 domains is gene specific. J Cell Biol (1999) 2.24
Intron-dependent recruitment of pre-mRNA splicing factors to sites of transcription. J Cell Biol (1996) 2.23
Elongator interactions with nascent mRNA revealed by RNA immunoprecipitation. Mol Cell (2004) 2.16
Proteomic analysis of interchromatin granule clusters. Mol Biol Cell (2004) 2.12
Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice. J Cell Biol (2011) 2.11
Streptavidin aptamers: affinity tags for the study of RNAs and ribonucleoproteins. RNA (2001) 2.11
A new paradigm for developmental biology. J Exp Biol (2007) 2.06
Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli. Mol Cell (2014) 2.05
High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation. Nature (2013) 2.00
Noncoding RNA and Polycomb recruitment. RNA (2013) 2.00
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development. RNA Biol (2012) 1.90
PDZK1 and GREB1 are estrogen-regulated genes expressed in hormone-responsive breast cancer. Cancer Res (2000) 1.90
Malat1 is not an essential component of nuclear speckles in mice. RNA (2012) 1.90
Alternative 3'-end processing of long noncoding RNA initiates construction of nuclear paraspeckles. EMBO J (2012) 1.60
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies. Mol Biol Cell (2013) 1.59
Purification and electron microscopic visualization of functional human spliceosomes. Proc Natl Acad Sci U S A (2002) 1.52
Multiple roles for Puralpha in cellular and viral regulation. Cell Cycle (2009) 1.39
Genomic analyses of hormone signaling and gene regulation. Annu Rev Physiol (2010) 1.38
Dogma derailed: the many influences of RNA on the genome. Mol Cell (2013) 1.36
CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant. Mol Cell Biol (2001) 1.04
Alternative RNA splicing complexes containing the scaffold attachment factor SAFB2. J Cell Sci (2007) 1.00