PubRank

Peter M Glazer

Author PubWeight™ 85.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status. Lancet 2002 3.04
2 MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res 2009 2.93
3 Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. Mol Cell Biol 2003 2.12
4 Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Mol Cell Biol 2004 2.09
5 Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Res 2005 2.02
6 Regulation of DNA repair in hypoxic cancer cells. Cancer Metastasis Rev 2007 1.99
7 Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance. Cancer Res 2008 1.70
8 Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression. J Mol Med (Berl) 2006 1.66
9 Molecular and cellular pharmacology of the hypoxia-activated prodrug TH-302. Mol Cancer Ther 2011 1.58
10 Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells. Cancer Biol Ther 2011 1.50
11 Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proc Natl Acad Sci U S A 2002 1.49
12 Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proc Natl Acad Sci U S A 2010 1.47
13 Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis. Mutat Res 2005 1.37
14 Repair of DNA lesions associated with triplex-forming oligonucleotides. Mol Carcinog 2009 1.36
15 Site-directed recombination via bifunctional PNA-DNA conjugates. Proc Natl Acad Sci U S A 2002 1.32
16 Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acids. Proc Natl Acad Sci U S A 2008 1.25
17 Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner. Cancer Res 2005 1.24
18 Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells. Radiother Oncol 2005 1.22
19 Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6. Carcinogenesis 2006 1.19
20 The potential for gene repair via triple helix formation. J Clin Invest 2003 1.19
21 Hypoxic tumor microenvironment and cancer cell differentiation. Curr Mol Med 2009 1.19
22 Site-specific gene modification by PNAs conjugated to psoralen. Biochemistry 2006 1.16
23 Emerging roles of microRNAs in the molecular responses to hypoxia. Curr Pharm Des 2009 1.14
24 Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network. Cancer Lett 2007 1.14
25 Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter. Mol Cell Biol 2011 1.13
26 Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. Mol Ther 2010 1.13
27 Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites. Cancer Biol Ther 2006 1.09
28 Targeting cancer with a lupus autoantibody. Sci Transl Med 2012 1.09
29 Triplex-forming oligonucleotides: principles and applications. Q Rev Biophys 2002 1.09
30 Triplex-forming oligonucleotides as potential tools for modulation of gene expression. Curr Med Chem Anticancer Agents 2005 1.08
31 Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. Chem Biol 2011 1.05
32 Repair and recombination induced by triple helix DNA. Front Biosci 2007 1.04
33 Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms. Breast Cancer Res 2010 1.03
34 Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced through gap junctions. Proc Natl Acad Sci U S A 2004 1.03
35 Repair of DNA interstrand cross-links: interactions between homology-dependent and homology-independent pathways. DNA Repair (Amst) 2006 1.02
36 Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRCA2 mutation. Cancer Res 2009 1.02
37 Targeted gene modification of hematopoietic progenitor cells in mice following systemic administration of a PNA-peptide conjugate. Mol Ther 2011 1.01
38 Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotides. Nucleic Acids Res 2004 0.98
39 Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Hum Mol Genet 2011 0.97
40 Interplay between DNA repair and inflammation, and the link to cancer. Crit Rev Biochem Mol Biol 2014 0.96
41 Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability. Ann N Y Acad Sci 2005 0.96
42 Targeted genome modification via triple helix formation. Ann N Y Acad Sci 2005 0.95
43 Triplex-stimulated intermolecular recombination at a single-copy genomic target. Mol Ther 2006 0.95
44 Gene therapy for autosomal dominant disorders of keratin. J Investig Dermatol Symp Proc 2005 0.94
45 Targeted correction of a thalassemia-associated beta-globin mutation induced by pseudo-complementary peptide nucleic acids. Nucleic Acids Res 2009 0.93
46 Src-Induced cisplatin resistance mediated by cell-to-cell communication. Cancer Res 2009 0.93
47 Distance and affinity dependence of triplex-induced recombination. Biochemistry 2005 0.93
48 The tumor microenvironment and DNA repair. Semin Radiat Oncol 2010 0.91
49 CHK2-dependent phosphorylation of BRCA1 in hypoxia. Radiat Res 2006 0.91
50 microRNAs in cancer cell response to ionizing radiation. Antioxid Redox Signal 2014 0.90
51 Triplex-induced recombination and repair in the pyrimidine motif. Nucleic Acids Res 2005 0.89
52 Preclinical evaluation of Laromustine for use in combination with radiation therapy in the treatment of solid tumors. Int J Radiat Biol 2011 0.89
53 Transcription dependence of chromosomal gene targeting by triplex-forming oligonucleotides. J Biol Chem 2002 0.89
54 Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage tolerance. Cancer Lett 2006 0.88
55 Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage. Mol Pharmacol 2011 0.87
56 Triplex-mediated gene modification. Methods Mol Biol 2008 0.86
57 Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer. Breast Cancer Res Treat 2012 0.86
58 Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acids. Nucleic Acids Res 2007 0.86
59 Targeted gene modification using triplex-forming oligonucleotides. Methods Mol Biol 2004 0.85
60 IGF1 receptor expression protects against microenvironmental stress found in the solid tumor. Radiat Res 2002 0.84
61 Targeted cross-linking of the human beta-globin gene in living cells mediated by a triple helix forming oligonucleotide. Biochemistry 2006 0.84
62 Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice. Mol Ther Nucleic Acids 2013 0.83
63 Molecular markers in clinical radiation oncology. Oncogene 2003 0.82
64 Polymer delivery systems for site-specific genome editing. J Control Release 2011 0.82
65 MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair. DNA Repair (Amst) 2008 0.82
66 Mlh1-dependent suppression of specific mutations induced in vivo by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Mutat Res 2005 0.81
67 Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA 2013 0.80
68 Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung. Adv Healthc Mater 2014 0.79
69 "Micro"-management of DNA repair genes by hypoxia. Cell Cycle 2009 0.77
70 Induction of aberrant crypt foci in DNA mismatch repair-deficient mice by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). Cancer Lett 2006 0.77
71 Introduction: the evolving picture of the hypoxic tumour microenvironment. Curr Mol Med 2009 0.76
72 Radiation sensitivity and sensitization in melanoma. Pigment Cell Melanoma Res 2013 0.76
73 Triplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells. Mol Ther 2013 0.76
74 Tumor suppressor p53 stole the AKT in hypoxia. J Clin Invest 2015 0.75
75 Therapeutic genome mutagenesis using synthetic donor DNA and triplex-forming molecules. Methods Mol Biol 2015 0.75
76 Targeted genome modification via triple helix formation. Methods Mol Biol 2014 0.75
77 Introduction. Yale J Biol Med 2013 0.75
78 Triplex-mediated genome targeting and editing. Methods Mol Biol 2014 0.75
79 Setting standards in gene repair. Oligonucleotides 2004 0.75
80 Peptide nucleic acid-mediated recombination for targeted genomic repair and modification. Methods Mol Biol 2014 0.75