1
|
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA.
|
Nat Mater
|
2009
|
2.87
|
2
|
Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling.
|
Proc Natl Acad Sci U S A
|
2010
|
2.49
|
3
|
Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma.
|
Proc Natl Acad Sci U S A
|
2013
|
1.95
|
4
|
Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles.
|
Immunology
|
2006
|
1.92
|
5
|
Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma.
|
Proc Natl Acad Sci U S A
|
2012
|
1.91
|
6
|
The uptake and intracellular fate of PLGA nanoparticles in epithelial cells.
|
Biomaterials
|
2009
|
1.82
|
7
|
PEGylated PLGA nanoparticles for the improved delivery of doxorubicin.
|
Nanomedicine
|
2009
|
1.70
|
8
|
Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus.
|
Mol Pharm
|
2009
|
1.59
|
9
|
Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion.
|
Nat Mater
|
2004
|
1.59
|
10
|
Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel.
|
FASEB J
|
2011
|
1.52
|
11
|
Pharmacokinetics of the carmustine implant.
|
Clin Pharmacokinet
|
2002
|
1.52
|
12
|
The influence of microchannels on neurite growth and architecture.
|
Biomaterials
|
2005
|
1.47
|
13
|
Surface-mediated gene transfer from nanocomposites of controlled texture.
|
Nat Mater
|
2004
|
1.45
|
14
|
Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors.
|
Biomaterials
|
2011
|
1.36
|
15
|
Therapeutic siRNA: principles, challenges, and strategies.
|
Yale J Biol Med
|
2012
|
1.35
|
16
|
Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery.
|
Nat Mater
|
2011
|
1.33
|
17
|
Human aortic smooth muscle cells promote arteriole formation by coengrafted endothelial cells.
|
Tissue Eng Part A
|
2009
|
1.28
|
18
|
New methods for direct delivery of chemotherapy for treating brain tumors.
|
Yale J Biol Med
|
2006
|
1.26
|
19
|
Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles.
|
Brain Res
|
2007
|
1.25
|
20
|
Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides.
|
Biomaterials
|
2011
|
1.24
|
21
|
Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking.
|
J Control Release
|
2008
|
1.23
|
22
|
In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery.
|
J Control Release
|
2011
|
1.20
|
23
|
High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine.
|
J Control Release
|
2008
|
1.19
|
24
|
Cellular fate of a modular DNA delivery system mediated by silica nanoparticles.
|
Biotechnol Prog
|
2005
|
1.19
|
25
|
Diffusion of nerve growth factor in rat striatum as determined by multiphoton microscopy.
|
Biophys J
|
2003
|
1.17
|
26
|
Fibronectin terminated multilayer films: protein adsorption and cell attachment studies.
|
Biomaterials
|
2006
|
1.16
|
27
|
Biomaterials with hierarchically defined micro- and nanoscale structure.
|
Biomaterials
|
2004
|
1.15
|
28
|
Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors.
|
Mol Ther
|
2010
|
1.13
|
29
|
Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery.
|
Biomaterials
|
2009
|
1.12
|
30
|
Centrifugal seeding increases seeding efficiency and cellular distribution of bone marrow stromal cells in porous biodegradable scaffolds.
|
Tissue Eng
|
2007
|
1.12
|
31
|
Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation.
|
FASEB J
|
2008
|
1.11
|
32
|
Polymeric nanoparticles for drug delivery to the central nervous system.
|
Adv Drug Deliv Rev
|
2011
|
1.09
|
33
|
Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification.
|
Biomaterials
|
2003
|
1.09
|
34
|
Convection-enhanced delivery of camptothecin-loaded polymer nanoparticles for treatment of intracranial tumors.
|
Drug Deliv Transl Res
|
2011
|
1.07
|
35
|
A self-assembled, modular DNA delivery system mediated by silica nanoparticles.
|
J Control Release
|
2004
|
1.07
|
36
|
Development of a model system for preliminary evaluation of tissue-engineered vascular conduits.
|
J Pediatr Surg
|
2006
|
1.06
|
37
|
Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates.
|
J Control Release
|
2011
|
1.03
|
38
|
Nanotechnology for delivery of drugs to the brain for epilepsy.
|
Neurotherapeutics
|
2009
|
1.03
|
39
|
Gene expression and mucosal immune responses after vaginal DNA immunization in mice using a controlled delivery matrix.
|
J Control Release
|
2003
|
1.01
|
40
|
Novel delivery strategies for glioblastoma.
|
Cancer J
|
2012
|
1.01
|
41
|
Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin.
|
Mol Pharm
|
2010
|
0.99
|
42
|
Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization.
|
Biomaterials
|
2010
|
0.99
|
43
|
Canonical and non-canonical barriers facing antimiR cancer therapeutics.
|
Curr Med Chem
|
2013
|
0.98
|
44
|
Nanosystems for simultaneous imaging and drug delivery to T cells.
|
AAPS J
|
2007
|
0.98
|
45
|
Topographical control of human neutrophil motility on micropatterned materials with various surface chemistry.
|
Biomaterials
|
2002
|
0.98
|
46
|
In vitro evaluation of biodegradable microspheres with surface-bound ligands.
|
J Control Release
|
2005
|
0.97
|
47
|
Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery.
|
J Control Release
|
2012
|
0.97
|
48
|
In vitro cytotoxicity and in vivo distribution after direct delivery of PEG-camptothecin conjugates to the rat brain.
|
Bioconjug Chem
|
2004
|
0.96
|
49
|
Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing.
|
Mol Pharm
|
2012
|
0.96
|
50
|
Bioengineering approaches to controlled protein delivery.
|
Pediatr Res
|
2008
|
0.95
|
51
|
Polymer nanoparticles encapsulating siRNA for treatment of HSV-2 genital infection.
|
J Control Release
|
2012
|
0.95
|
52
|
Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels.
|
Biomaterials
|
2005
|
0.94
|
53
|
Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation.
|
FASEB J
|
2013
|
0.94
|
54
|
Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency.
|
Nanomedicine
|
2009
|
0.92
|
55
|
Drug delivery: Stealth particles give mucus the slip.
|
Nat Mater
|
2009
|
0.91
|
56
|
Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell-based antitumor immunotherapy.
|
Nanomedicine
|
2010
|
0.90
|
57
|
Design opportunities for actively targeted nanoparticle vaccines.
|
Nanomedicine (Lond)
|
2008
|
0.89
|
58
|
Pericytes modulate endothelial sprouting.
|
Cardiovasc Res
|
2013
|
0.89
|
59
|
Mathematical modeling of molecular diffusion through mucus.
|
Adv Drug Deliv Rev
|
2008
|
0.89
|
60
|
Enzyme-synthesized poly(amine-co-esters) as nonviral vectors for gene delivery.
|
J Biomed Mater Res A
|
2010
|
0.88
|
61
|
Surface-modified biodegradable microspheres for DNA vaccine delivery.
|
Methods Mol Med
|
2006
|
0.88
|
62
|
Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures.
|
Tissue Eng
|
2006
|
0.88
|
63
|
Poly(lactide-co-glycolide) nanoparticle assembly for highly efficient delivery of potent therapeutic agents from medical devices.
|
Biomaterials
|
2010
|
0.87
|
64
|
Replacement of bone marrow by bone in rat femurs: the bone bioreactor.
|
Tissue Eng Part A
|
2008
|
0.86
|
65
|
A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells.
|
Nanomedicine
|
2007
|
0.86
|
66
|
Organosilicate-polymer drug delivery systems: controlled release and enhanced mechanical properties.
|
J Control Release
|
2003
|
0.85
|
67
|
Are we studying what matters? Health priorities and NIH-funded biomedical engineering research.
|
Ann Biomed Eng
|
2010
|
0.83
|
68
|
Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice.
|
Mol Ther Nucleic Acids
|
2013
|
0.83
|
69
|
Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity.
|
Mol Pharm
|
2010
|
0.83
|
70
|
An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds.
|
Biomaterials
|
2013
|
0.83
|
71
|
Shining light on a new class of hydrogels.
|
Nat Biotechnol
|
2009
|
0.82
|
72
|
Polymer delivery systems for site-specific genome editing.
|
J Control Release
|
2011
|
0.82
|
73
|
The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats.
|
Brain Res
|
2010
|
0.81
|
74
|
Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer.
|
Nanomedicine
|
2013
|
0.81
|
75
|
Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gel.
|
Biomaterials
|
2013
|
0.80
|
76
|
Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5.
|
Artif DNA PNA XNA
|
2013
|
0.80
|
77
|
Development of a parathyroid hormone-controlled release system as a potential surgical treatment for hypoparathyroidism.
|
J Pediatr Surg
|
2005
|
0.79
|
78
|
Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with positron emission tomography.
|
Mol Imaging Biol
|
2013
|
0.79
|
79
|
The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus.
|
Biomaterials
|
2013
|
0.79
|
80
|
Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung.
|
Adv Healthc Mater
|
2014
|
0.79
|
81
|
Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA.
|
Hear Res
|
2013
|
0.79
|
82
|
Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance.
|
J Neurooncol
|
2014
|
0.79
|
83
|
The effect of synthetic polymers on the migration of monocytes through human cervical mucus.
|
Biomaterials
|
2004
|
0.79
|
84
|
Enhanced growth and hepatic differentiation of fetal liver epithelial cells through combinational and temporal adjustment of soluble factors.
|
Biotechnol J
|
2011
|
0.78
|
85
|
Parameter estimation methodology in a model of hydrophobic drug release from a polymer coating.
|
J Control Release
|
2009
|
0.78
|
86
|
Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures.
|
Tissue Eng Part A
|
2009
|
0.78
|
87
|
Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography.
|
Bioconjug Chem
|
2014
|
0.78
|
88
|
Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters.
|
Biomaterials
|
2011
|
0.77
|
89
|
Effect of extracellular matrix elements on the transport of paclitaxel through an arterial wall tissue mimic.
|
Biomacromolecules
|
2008
|
0.77
|
90
|
Efficacy of camptothecin and polymer-conjugated camptothecin in tumor spheroids and solid tumors.
|
J Biomater Sci Polym Ed
|
2007
|
0.77
|
91
|
Nanomedicine: Downsizing tumour therapeutics.
|
Nat Nanotechnol
|
2012
|
0.77
|
92
|
Simultaneous release of multiple molecules from poly(lactide-co-glycolide) nanoparticles assembled onto medical devices.
|
Biomaterials
|
2009
|
0.76
|
93
|
Targeted genome modification via triple helix formation.
|
Methods Mol Biol
|
2014
|
0.75
|
94
|
Development of PTH eluting microspheres for the treatment of hypoparathyroidism.
|
J Surg Res
|
2007
|
0.75
|