W Mark Saltzman

Author PubWeight™ 99.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA. Nat Mater 2009 2.87
2 Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proc Natl Acad Sci U S A 2010 2.49
3 Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proc Natl Acad Sci U S A 2013 1.95
4 Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles. Immunology 2006 1.92
5 Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma. Proc Natl Acad Sci U S A 2012 1.91
6 The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials 2009 1.82
7 PEGylated PLGA nanoparticles for the improved delivery of doxorubicin. Nanomedicine 2009 1.70
8 Controlled surface modification with poly(ethylene)glycol enhances diffusion of PLGA nanoparticles in human cervical mucus. Mol Pharm 2009 1.59
9 Multiphoton microscopy guides neurotrophin modification with poly(ethylene glycol) to enhance interstitial diffusion. Nat Mater 2004 1.59
10 Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel. FASEB J 2011 1.52
11 Pharmacokinetics of the carmustine implant. Clin Pharmacokinet 2002 1.52
12 The influence of microchannels on neurite growth and architecture. Biomaterials 2005 1.47
13 Surface-mediated gene transfer from nanocomposites of controlled texture. Nat Mater 2004 1.45
14 Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. Biomaterials 2011 1.36
15 Therapeutic siRNA: principles, challenges, and strategies. Yale J Biol Med 2012 1.35
16 Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery. Nat Mater 2011 1.33
17 Human aortic smooth muscle cells promote arteriole formation by coengrafted endothelial cells. Tissue Eng Part A 2009 1.28
18 New methods for direct delivery of chemotherapy for treating brain tumors. Yale J Biol Med 2006 1.26
19 Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles. Brain Res 2007 1.25
20 Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides. Biomaterials 2011 1.24
21 Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking. J Control Release 2008 1.23
22 In vivo distribution of surface-modified PLGA nanoparticles following intravaginal delivery. J Control Release 2011 1.20
23 High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine. J Control Release 2008 1.19
24 Cellular fate of a modular DNA delivery system mediated by silica nanoparticles. Biotechnol Prog 2005 1.19
25 Diffusion of nerve growth factor in rat striatum as determined by multiphoton microscopy. Biophys J 2003 1.17
26 Fibronectin terminated multilayer films: protein adsorption and cell attachment studies. Biomaterials 2006 1.16
27 Biomaterials with hierarchically defined micro- and nanoscale structure. Biomaterials 2004 1.15
28 Nanoparticles deliver triplex-forming PNAs for site-specific genomic recombination in CD34+ human hematopoietic progenitors. Mol Ther 2010 1.13
29 Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery. Biomaterials 2009 1.12
30 Centrifugal seeding increases seeding efficiency and cellular distribution of bone marrow stromal cells in porous biodegradable scaffolds. Tissue Eng 2007 1.12
31 Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation. FASEB J 2008 1.11
32 Polymeric nanoparticles for drug delivery to the central nervous system. Adv Drug Deliv Rev 2011 1.09
33 Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification. Biomaterials 2003 1.09
34 Convection-enhanced delivery of camptothecin-loaded polymer nanoparticles for treatment of intracranial tumors. Drug Deliv Transl Res 2011 1.07
35 A self-assembled, modular DNA delivery system mediated by silica nanoparticles. J Control Release 2004 1.07
36 Development of a model system for preliminary evaluation of tissue-engineered vascular conduits. J Pediatr Surg 2006 1.06
37 Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates. J Control Release 2011 1.03
38 Nanotechnology for delivery of drugs to the brain for epilepsy. Neurotherapeutics 2009 1.03
39 Gene expression and mucosal immune responses after vaginal DNA immunization in mice using a controlled delivery matrix. J Control Release 2003 1.01
40 Novel delivery strategies for glioblastoma. Cancer J 2012 1.01
41 Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Mol Pharm 2010 0.99
42 Dual delivery of VEGF and MCP-1 to support endothelial cell transplantation for therapeutic vascularization. Biomaterials 2010 0.99
43 Canonical and non-canonical barriers facing antimiR cancer therapeutics. Curr Med Chem 2013 0.98
44 Nanosystems for simultaneous imaging and drug delivery to T cells. AAPS J 2007 0.98
45 Topographical control of human neutrophil motility on micropatterned materials with various surface chemistry. Biomaterials 2002 0.98
46 In vitro evaluation of biodegradable microspheres with surface-bound ligands. J Control Release 2005 0.97
47 Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery. J Control Release 2012 0.97
48 In vitro cytotoxicity and in vivo distribution after direct delivery of PEG-camptothecin conjugates to the rat brain. Bioconjug Chem 2004 0.96
49 Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing. Mol Pharm 2012 0.96
50 Bioengineering approaches to controlled protein delivery. Pediatr Res 2008 0.95
51 Polymer nanoparticles encapsulating siRNA for treatment of HSV-2 genital infection. J Control Release 2012 0.95
52 Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels. Biomaterials 2005 0.94
53 Sustained delivery of proangiogenic microRNA-132 by nanoparticle transfection improves endothelial cell transplantation. FASEB J 2013 0.94
54 Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency. Nanomedicine 2009 0.92
55 Drug delivery: Stealth particles give mucus the slip. Nat Mater 2009 0.91
56 Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell-based antitumor immunotherapy. Nanomedicine 2010 0.90
57 Design opportunities for actively targeted nanoparticle vaccines. Nanomedicine (Lond) 2008 0.89
58 Pericytes modulate endothelial sprouting. Cardiovasc Res 2013 0.89
59 Mathematical modeling of molecular diffusion through mucus. Adv Drug Deliv Rev 2008 0.89
60 Enzyme-synthesized poly(amine-co-esters) as nonviral vectors for gene delivery. J Biomed Mater Res A 2010 0.88
61 Surface-modified biodegradable microspheres for DNA vaccine delivery. Methods Mol Med 2006 0.88
62 Impact of cell type and density on nerve growth factor distribution and bioactivity in 3-dimensional collagen gel cultures. Tissue Eng 2006 0.88
63 Poly(lactide-co-glycolide) nanoparticle assembly for highly efficient delivery of potent therapeutic agents from medical devices. Biomaterials 2010 0.87
64 Replacement of bone marrow by bone in rat femurs: the bone bioreactor. Tissue Eng Part A 2008 0.86
65 A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. Nanomedicine 2007 0.86
66 Organosilicate-polymer drug delivery systems: controlled release and enhanced mechanical properties. J Control Release 2003 0.85
67 Are we studying what matters? Health priorities and NIH-funded biomedical engineering research. Ann Biomed Eng 2010 0.83
68 Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice. Mol Ther Nucleic Acids 2013 0.83
69 Vaccine delivery by polymeric vehicles in the mouse reproductive tract induces sustained local and systemic immunity. Mol Pharm 2010 0.83
70 An electrospun scaffold integrating nucleic acid delivery for treatment of full-thickness wounds. Biomaterials 2013 0.83
71 Shining light on a new class of hydrogels. Nat Biotechnol 2009 0.82
72 Polymer delivery systems for site-specific genome editing. J Control Release 2011 0.82
73 The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain Res 2010 0.81
74 Nanoparticles for urothelium penetration and delivery of the histone deacetylase inhibitor belinostat for treatment of bladder cancer. Nanomedicine 2013 0.81
75 Paracrine exchanges of molecular signals between alginate-encapsulated pericytes and freely suspended endothelial cells within a 3D protein gel. Biomaterials 2013 0.80
76 Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5. Artif DNA PNA XNA 2013 0.80
77 Development of a parathyroid hormone-controlled release system as a potential surgical treatment for hypoparathyroidism. J Pediatr Surg 2005 0.79
78 Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with positron emission tomography. Mol Imaging Biol 2013 0.79
79 The nanomaterial-dependent modulation of dendritic cells and its potential influence on therapeutic immunosuppression in lupus. Biomaterials 2013 0.79
80 Modified poly(lactic-co-glycolic acid) nanoparticles for enhanced cellular uptake and gene editing in the lung. Adv Healthc Mater 2014 0.79
81 Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA. Hear Res 2013 0.79
82 Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance. J Neurooncol 2014 0.79
83 The effect of synthetic polymers on the migration of monocytes through human cervical mucus. Biomaterials 2004 0.79
84 Enhanced growth and hepatic differentiation of fetal liver epithelial cells through combinational and temporal adjustment of soluble factors. Biotechnol J 2011 0.78
85 Parameter estimation methodology in a model of hydrophobic drug release from a polymer coating. J Control Release 2009 0.78
86 Biodegradable meshes printed with extracellular matrix proteins support micropatterned hepatocyte cultures. Tissue Eng Part A 2009 0.78
87 Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography. Bioconjug Chem 2014 0.78
88 Biodegradation, biocompatibility, and drug delivery in poly(ω-pentadecalactone-co-p-dioxanone) copolyesters. Biomaterials 2011 0.77
89 Effect of extracellular matrix elements on the transport of paclitaxel through an arterial wall tissue mimic. Biomacromolecules 2008 0.77
90 Efficacy of camptothecin and polymer-conjugated camptothecin in tumor spheroids and solid tumors. J Biomater Sci Polym Ed 2007 0.77
91 Nanomedicine: Downsizing tumour therapeutics. Nat Nanotechnol 2012 0.77
92 Simultaneous release of multiple molecules from poly(lactide-co-glycolide) nanoparticles assembled onto medical devices. Biomaterials 2009 0.76
93 Targeted genome modification via triple helix formation. Methods Mol Biol 2014 0.75
94 Development of PTH eluting microspheres for the treatment of hypoparathyroidism. J Surg Res 2007 0.75