Constitutive activation of CaMKKα signaling is sufficient but not necessary for mTORC1 activation and growth in mouse skeletal muscle.

Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms. Bone (2015) 0.81

Ca2+/Calmodulin-Dependent Protein Kinase Kinases (CaMKKs) Effects on AMP-Activated Protein Kinase (AMPK) Regulation of Chicken Sperm Functions. PLoS One (2016) 0.76

Calcium signaling in skeletal muscle development, maintenance and regeneration. Cell Calcium (2016) 0.75

mTOR signaling in growth control and disease. Cell (2012) 29.21

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol (2002) 17.41

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol (2001) 10.85

Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm. J Biol Chem (1975) 4.89

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J (1999) 4.80

A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. Cancer Res (2000) 4.62

Gene transfer into muscle by electroporation in vivo. Nat Biotechnol (1998) 3.89

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature (1998) 3.31

Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans. Am J Physiol (1995) 2.78

Relative muscle mass is inversely associated with insulin resistance and prediabetes. Findings from the third National Health and Nutrition Examination Survey. J Clin Endocrinol Metab (2011) 2.48

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle. Proc Natl Acad Sci U S A (2006) 2.19

The influence of immobilization and stretch on protein turnover of rat skeletal muscle. J Physiol (1977) 1.94

Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism. Biochem J (2004) 1.89

Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner. J Biol Chem (2004) 1.77

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load. J Biol Chem (2002) 1.72

Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade. Proc Natl Acad Sci U S A (1996) 1.57

The benefits of strength training for older adults. Am J Prev Med (2003) 1.52

Calcium-dependent regulation of protein synthesis and degradation in muscle. Nature (1979) 1.43

Activation of calcium signaling through Trpv1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy. Nat Med (2012) 1.31

Protein synthesis during work-induced growth of skeletal muscle. J Cell Biol (1968) 1.27

Normal hypertrophy accompanied by phosphoryation and activation of AMP-activated protein kinase alpha1 following overload in LKB1 knockout mice. J Physiol (2008) 1.23

Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation. Diabetes (2007) 1.22

The effects of calcium ions, ionophore A23187 and inhibition of energy metabolism on protein degradation in the rat diaphragm and epitrochlearis muscles in vitro. Biochem J (1980) 1.19

Diminished overload-induced hypertrophy in aged fast-twitch skeletal muscle is associated with AMPK hyperphosphorylation. J Appl Physiol (1985) (2004) 1.18

Inhibition of stretch-activated channels during eccentric muscle contraction attenuates p70S6K activation. J Appl Physiol (1985) (2005) 1.10

The effects of calcium on protein turnover in skeletal muscles of the rat. Biochem J (1982) 1.03

Differential regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase isoforms. Biochemistry (2001) 1.00

Long-term memory deficits in Pavlovian fear conditioning in Ca2+/calmodulin kinase kinase alpha-deficient mice. Mol Cell Biol (2006) 0.96

Inhibition of interleukin-1beta -induced NF-kappa B activation by calcium/calmodulin-dependent protein kinase kinase occurs through Akt activation associated with interleukin-1 receptor-associated kinase phosphorylation and uncoupling of MyD88. J Biol Chem (2002) 0.93

Intracellular calcium accumulation following eccentric contractions in rat skeletal muscle in vivo: role of stretch-activated channels. Am J Physiol Regul Integr Comp Physiol (2008) 0.85

Treatment of burned rats with insulin-like growth factor I inhibits the catabolic response in skeletal muscle. Am J Physiol (1998) 0.85

How is the balance between protein synthesis and degradation achieved? Theor Biol Med Model (2010) 0.81

Visualizing dynamic interaction between calmodulin and calmodulin-related kinases via a monitoring method in live mammalian cells. Proc Natl Acad Sci U S A (2010) 0.81

Protein synthesis in compensatory hypertrophy of rat plantaris. Can J Physiol Pharmacol (1984) 0.78

Constitutively active CaMKKα stimulates skeletal muscle glucose uptake in insulin-resistant mice in vivo. Diabetes (2013) 0.78