Published in PLoS Pathog on September 11, 2014
Mechanisms of Bacterial Colonization of the Respiratory Tract. Annu Rev Microbiol (2015) 0.91
Cell Surface Glycoside Hydrolases of Streptococcus gordonii Promote Growth in Saliva. Appl Environ Microbiol (2016) 0.77
ManLMN is a glucose transporter and central metabolic regulator in Streptococcus pneumoniae. Mol Microbiol (2016) 0.77
A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. J Biol Chem (2015) 0.76
Engineering of the Bacillus circulans β-galactosidase product specificity. Biochemistry (2017) 0.75
Biochemical and Structural Insights into a Novel Thermostable β-1,3-Galactosidase from Marinomonas sp. BSi20414. Mar Drugs (2017) 0.75
Analysis of Domain Architecture and Phylogenetics of Family 2 Glycoside Hydrolases (GH2). PLoS One (2016) 0.75
Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens. PLoS One (2017) 0.75
Streptococcus oralis Neuraminidase Modulates Adherence to Multiple Carbohydrates on Platelets. Infect Immun (2017) 0.75
A short history of SHELX. Acta Crystallogr A (2007) 7339.18
Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr (2011) 67.55
Protein structure prediction on the Web: a case study using the Phyre server. Nat Protoc (2009) 32.64
The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res (2008) 27.83
Complete genome sequence of a virulent isolate of Streptococcus pneumoniae. Science (2001) 21.99
Carbohydrate-binding modules: fine-tuning polysaccharide recognition. Biochem J (2004) 8.19
Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol (2001) 7.97
The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract. Proc Natl Acad Sci U S A (2002) 7.21
Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Mol Microbiol (2002) 6.03
The Rossmann Fourier autoindexing algorithm in MOSFLM. Acta Crystallogr D Biol Crystallogr (1999) 5.96
An rpsL cassette, janus, for gene replacement through negative selection in Streptococcus pneumoniae. Appl Environ Microbiol (2001) 4.59
Large-scale identification of virulence genes from Streptococcus pneumoniae. Infect Immun (1998) 4.19
PCR ligation mutagenesis in transformable streptococci: application and efficiency. J Microbiol Methods (2002) 3.78
Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6. J Bacteriol (2006) 3.40
Direct evidence that the FimH protein is the mannose-specific adhesin of Escherichia coli type 1 fimbriae. Infect Immun (1990) 2.94
Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins. Infect Immun (2000) 2.48
Deglycosylation of human glycoconjugates by the sequential activities of exoglycosidases expressed by Streptococcus pneumoniae. Mol Microbiol (2006) 2.29
Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging. Proc Natl Acad Sci U S A (2010) 2.14
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies. J Exp Med (2007) 2.11
A neuraminidase from Streptococcus pneumoniae has the features of a surface protein. Infect Immun (1994) 2.04
The Streptococcus pneumoniae beta-galactosidase is a surface protein. J Bacteriol (2000) 1.89
Growth of Streptococcus pneumoniae on human glycoconjugates is dependent upon the sequential activity of bacterial exoglycosidases. J Bacteriol (2007) 1.82
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells. J Bacteriol (2008) 1.72
Pneumococcal neuraminidases A and B both have essential roles during infection of the respiratory tract and sepsis. Infect Immun (2006) 1.71
Adherence molecules of pathogenic pneumococci. Curr Opin Microbiol (2005) 1.68
Cloning and nucleotide sequence of the Streptococcus pneumoniae hyaluronidase gene and purification of the enzyme from recombinant Escherichia coli. Infect Immun (1994) 1.59
Genome-wide transcriptional changes in Streptococcus gordonii in response to competence signaling peptide. J Bacteriol (2007) 1.55
Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis. Structure (2011) 1.53
Inactivation of the srtA gene affects localization of surface proteins and decreases adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro. Infect Immun (2003) 1.51
The inhibitory effect of C-reactive protein on bacterial phosphorylcholine platelet-activating factor receptor-mediated adherence is blocked by surfactant. J Infect Dis (2002) 1.49
The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion. J Exp Med (2009) 1.48
Structural basis of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. EMBO J (2000) 1.48
The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation. Infect Immun (2009) 1.36
The interaction of a carbohydrate-binding module from a Clostridium perfringens N-acetyl-beta-hexosaminidase with its carbohydrate receptor. J Biol Chem (2006) 1.33
Three surface exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, promote resistance to opsonophagocytic killing by human neutrophils. Infect Immun (2010) 1.32
Characterization of the heparin-binding site of the mycobacterial heparin-binding hemagglutinin adhesin. J Biol Chem (2000) 1.31
Identification and structural basis of binding to host lung glycogen by streptococcal virulence factors. Nat Struct Mol Biol (2006) 1.28
Pseudomonas aeruginosa pili and flagella mediate distinct binding and signaling events at the apical and basolateral surface of airway epithelium. PLoS Pathog (2012) 1.25
Pneumococcal modification of host sugars: a major contributor to colonization of the human airway? Mol Oral Microbiol (2010) 1.24
Cloning and expression of the beta-N-acetylglucosaminidase gene from Streptococcus pneumoniae. Generation of truncated enzymes with modified aglycon specificity. J Biol Chem (1995) 1.22
The ability to utilize mucin affects the regulation of virulence gene expression in Streptococcus pneumoniae. FEMS Microbiol Lett (2007) 1.16
Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB. Proc Natl Acad Sci U S A (2008) 1.12
Streptococcus pneumoniae can utilize multiple sources of hyaluronic acid for growth. Infect Immun (2012) 1.12
Experimental pneumococcal meningitis in mice: a model of intranasal infection. J Infect Dis (2001) 1.11
Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae. PLoS Pathog (2008) 1.11
Characterization of novel beta-galactosidase activity that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniae. Infect Immun (2009) 1.11
Genome of Streptococcus oralis strain Uo5. J Bacteriol (2011) 1.08
A capillary electrophoretic study on the specificity of beta-galactosidases from Aspergillus oryzae, Escherichia coli, Streptococcus pneumoniae, and Canavalia ensiformis (jack bean). Anal Biochem (1997) 1.07
Identification of a pneumococcal glycosidase that modifies O-linked glycans. Infect Immun (2009) 1.02
Salmonella enterica serotype Typhimurium Std fimbriae bind terminal alpha(1,2)fucose residues in the cecal mucosa. Mol Microbiol (2008) 1.02
Molecular cloning and expression of endo-beta-N-acetylglucosaminidase D, which acts on the core structure of complex type asparagine-linked oligosaccharides. J Biochem (2001) 1.00
Serotype-specific invasiveness and colonization prevalence in Streptococcus pneumoniae correlate with the lag phase during in vitro growth. Microbes Infect (2006) 0.99
Antigenicity, expression, and molecular characterization of surface-located pullulanase of Streptococcus pneumoniae. Infect Immun (2000) 0.98
Pneumococcal neuraminidase A: an essential upper airway colonization factor for Streptococcus pneumoniae. Mol Oral Microbiol (2012) 0.98
Surface-associated lipoprotein PpmA of Streptococcus pneumoniae is involved in colonization in a strain-specific manner. Microbiology (2009) 0.96
The structural basis for T-antigen hydrolysis by Streptococcus pneumoniae: a target for structure-based vaccine design. J Biol Chem (2008) 0.95
The molecular basis of glycogen breakdown and transport in Streptococcus pneumoniae. Mol Microbiol (2010) 0.94
BgaA acts as an adhesin to mediate attachment of some pneumococcal strains to human epithelial cells. Microbiology (2011) 0.94
Characterization of the Streptococcus pneumoniae BgaC protein as a novel surface beta-galactosidase with specific hydrolysis activity for the Galbeta1-3GlcNAc moiety of oligosaccharides. J Bacteriol (2009) 0.93
Impact of pneumococcal microbial surface components recognizing adhesive matrix molecules on colonization. Mol Oral Microbiol (2012) 0.90
N-acetylglucosamine recognition by a family 32 carbohydrate-binding module from Clostridium perfringens NagH. J Mol Biol (2009) 0.90
The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun (2002) 0.90
Insights into the recognition of the human glycome by microbial carbohydrate-binding modules. Curr Opin Struct Biol (2012) 0.89
Diplococcal beta-galactosidase with a specificity reacting to beta 1-4 linkage but not to beta 1-3 linkage as a useful exoglycosidase for the structural elucidation of glycolipids. Anal Biochem (1987) 0.83
Physicochemical effects in the representation of molecular structures for drug designing. Mini Rev Med Chem (2003) 0.78
Structural analysis of a putative family 32 carbohydrate-binding module from the Streptococcus pneumoniae enzyme EndoD. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.76
Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature (2015) 1.52
TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model. PLoS Pathog (2014) 0.92
Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence. PLoS Pathog (2017) 0.75