Published in Infect Immun on January 01, 2000
Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors. Mol Microbiol (2002) 6.03
Insights into the interaction between influenza virus and pneumococcus. Clin Microbiol Rev (2006) 5.92
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Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae. Infect Immun (2002) 2.15
Development of a multiplex PCR for the detection of asa1, gelE, cylA, esp, and hyl genes in enterococci and survey for virulence determinants among European hospital isolates of Enterococcus faecium. J Clin Microbiol (2004) 2.10
Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91
Live attenuated Streptococcus pneumoniae strains induce serotype-independent mucosal and systemic protection in mice. Infect Immun (2007) 1.83
Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae. Infect Immun (2006) 1.80
The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin. J Bacteriol (2001) 1.77
Pneumococcal neuraminidases A and B both have essential roles during infection of the respiratory tract and sepsis. Infect Immun (2006) 1.71
Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA. Infect Immun (2001) 1.62
Pneumococcal surface protein A contributes to secondary Streptococcus pneumoniae infection after influenza virus infection. J Infect Dis (2009) 1.56
PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun (2005) 1.54
PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin [corrected]. Infect Immun (2004) 1.53
From nose to lung: the regulation behind Streptococcus pneumoniae virulence factors. Mol Microbiol (2003) 1.46
The multifunctional Staphylococcus aureus autolysin aaa mediates adherence to immobilized fibrinogen and fibronectin. Infect Immun (2005) 1.43
Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci. Infect Immun (2005) 1.41
The NanA neuraminidase of Streptococcus pneumoniae is involved in biofilm formation. Infect Immun (2009) 1.36
NanA, a neuraminidase from Streptococcus pneumoniae, shows high levels of sequence diversity, at least in part through recombination with Streptococcus oralis. J Bacteriol (2005) 1.35
Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract. MBio (2011) 1.34
In vivo expression technology. Infect Immun (2002) 1.30
Endogenous pro- and anti-inflammatory cytokines differentially regulate an in vivo humoral response to Streptococcus pneumoniae. Infect Immun (2002) 1.30
The putative proteinase maturation protein A of Streptococcus pneumoniae is a conserved surface protein with potential to elicit protective immune responses. Infect Immun (2000) 1.28
Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model. Infect Immun (2007) 1.25
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The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15. Infect Immun (2002) 1.14
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Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model. Infect Immun (2003) 1.09
The two-component signal transduction system RR06/HK06 regulates expression of cbpA in Streptococcus pneumoniae. Proc Natl Acad Sci U S A (2005) 1.09
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Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice. J Clin Invest (2012) 1.01
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Experimental design approach in recombinant protein expression: determining medium composition and induction conditions for expression of pneumolysin from Streptococcus pneumoniae in Escherichia coli and preliminary purification process. BMC Biotechnol (2014) 0.98
Characterization and functional analysis of atl, a novel gene encoding autolysin in Streptococcus suis. J Bacteriol (2012) 0.96
The absence of PspA or presence of antibody to PspA facilitates the complement-dependent phagocytosis of pneumococci in vitro. Clin Vaccine Immunol (2012) 0.95
Peritoneal culture alters Streptococcus pneumoniae protein profiles and virulence properties. Infect Immun (2000) 0.94
Characterization of LytA-like N-acetylmuramoyl-L-alanine amidases from two new Streptococcus mitis bacteriophages provides insights into the properties of the major pneumococcal autolysin. J Bacteriol (2004) 0.92
Identification of IspC, an 86-kilodalton protein target of humoral immune response to infection with Listeria monocytogenes serotype 4b, as a novel surface autolysin. J Bacteriol (2006) 0.91
Differential activation of inflammatory pathways in A549 type II pneumocytes by Streptococcus pneumoniae strains with different adherence properties. BMC Infect Dis (2006) 0.91
Transcriptional profile of Mycobacterium tuberculosis replicating in type II alveolar epithelial cells. PLoS One (2015) 0.90
Distribution, genetic diversity, and variable expression of the gene encoding hyaluronate lyase within the Streptococcus suis population. J Bacteriol (2004) 0.88
Differential role of CbpA and PspA in modulation of in vitro CXC chemokine responses of respiratory epithelial cells to infection with Streptococcus pneumoniae. Infect Immun (2006) 0.87
New approaches towards the identification of antibiotic and vaccine targets in Streptococcus pneumoniae. EMBO Rep (2002) 0.87
Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae β-galactosidase, BgaA. PLoS Pathog (2014) 0.86
Pleiotropic effects of cell wall amidase LytA on Streptococcus pneumoniae sensitivity to the host immune response. Infect Immun (2014) 0.85
Characterization of protective immune responses induced by pneumococcal surface protein A in fusion with pneumolysin derivatives. PLoS One (2013) 0.85
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A modified surface killing assay (MSKA) as a functional in vitro assay for identifying protective antibodies against pneumococcal surface protein A (PspA). Vaccine (2013) 0.83
A transcription factor contributes to pathogenesis and virulence in Streptococcus pneumoniae. PLoS One (2013) 0.82
Contribution of different pneumococcal virulence factors to experimental meningitis in mice. BMC Infect Dis (2013) 0.82
Spermidine biosynthesis and transport modulate pneumococcal autolysis. J Bacteriol (2014) 0.80
Viability and virulence of pneumolysin, pneumococcal surface protein A, and pneumolysin/pneumococcal surface protein A mutants in the ear. JAMA Otolaryngol Head Neck Surg (2013) 0.80
Accumulation of partly folded states in the equilibrium unfolding of the pneumococcal choline-binding module C-LytA. Biochem J (2005) 0.78
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Novel Strategy To Protect against Influenza Virus-Induced Pneumococcal Disease without Interfering with Commensal Colonization. Infect Immun (2016) 0.76
Evidence of localized prophage-host recombination in the lytA gene, encoding the major pneumococcal autolysin. J Bacteriol (2010) 0.76
Pneumococcal neuraminidase A (NanA) promotes biofilm formation and synergizes with influenza A virus in nasal colonization and middle ear infection. Infect Immun (2017) 0.75
Characterization of Afb, a novel bifunctional protein in Streptococcus agalactiae. Iran J Microbiol (2016) 0.75
Learning virulent proteins from integrated query networks. BMC Bioinformatics (2012) 0.75
Free Sialic Acid Acts as a Signal That Promotes Streptococcus pneumoniae Invasion of Nasal Tissue and Nonhematogenous Invasion of the Central Nervous System. Infect Immun (2016) 0.75
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Conformational analysis of the Streptococcus pneumoniae hyaluronate lyase and characterization of its hyaluronan-specific carbohydrate-binding module. J Biol Chem (2014) 0.75
Crystallization and preliminary crystallographic analysis of recombinant hyaluronate lyase from Streptococcus suis. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Micelle-Triggered β-Hairpin to α-Helix Transition in a 14-Residue Peptide from a Choline-Binding Repeat of the Pneumococcal Autolysin LytA. Chemistry (2015) 0.75
Characterization of Pneumococcal Genes Involved in Bloodstream Invasion in a Mouse Model. PLoS One (2015) 0.75
The Pneumococcal Alpha-Glycerophosphate Oxidase Enhances Nasopharyngeal Colonization through Binding to Host Glycoconjugates. EBioMedicine (2017) 0.75
Differences in virulence of pneumolysin and autolysin mutants constructed by insertion duplication mutagenesis and in-frame deletion in Streptococcus pneumoniae. BMC Biotechnol (2014) 0.75
Long Persistence of a Streptococcus pneumoniae 23F Clone in a Cystic Fibrosis Patient. mSphere (2017) 0.75
Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent. PLoS One (2017) 0.75
The bias of experimental design, including strain background, in the determination of critical Streptococcus suis serotype 2 virulence factors. PLoS One (2017) 0.75
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