Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.

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Published in Alzheimers Dement on October 01, 2014

Authors

Sid E O'Bryant1, Veer Gupta2, Kim Henriksen3, Melissa Edwards4, Andreas Jeromin5, Simone Lista6, Chantal Bazenet7, Holly Soares8, Simon Lovestone7, Harald Hampel9, Thomas Montine10, Kaj Blennow11, Tatiana Foroud12, Maria Carrillo13, Neill Graff-Radford14, Christoph Laske15, Monique Breteler16, Leslie Shaw16, John Q Trojanowski16, Nicole Schupf17, Robert A Rissman18, Anne M Fagan19, Pankaj Oberoi20, Robert Umek21, Michael W Weiner22, Paula Grammas23, Holly Posner24, Ralph Martins2, STAR-B and BBBIG working groups

Author Affiliations

1: Institute for Aging & Alzheimer's Disease Research and Department of Internal Medicine, University of North Texas Health Science Center, Fort Worth, TX, USA. Electronic address: sid.o'bryant@unthsc.edu.
2: Centre of Excellence for Alzheimer's Disease Research & Care, School of Medical Sciences, Edith Cowan University, Joondalup, WA, Australia.
3: Nordic Bioscience Biomarkers and Research, Neurodegenerative Diseases, Herlev, Denmark.
4: Department of Psychology, University of North Texas, Denton, TX, USA.
5: Quanterix, Inc., Lexington, MA, USA.
6: AXA Research Fund & UPMC Chair, Paris, France.
7: Department of Old Age Psychiatry, King's College London, Institute of Psychiatry, London, UK.
8: Bristol-Myers Squibb, Wallingford, CT, USA.
9: AXA Research Fund & UPMC Chair, Paris, France; Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut dela Mémoire et de la Maladie d'Alzheimer (IM2A) & Institut du Cerveau et dela Moelle épinière (ICM), Département de Neurologie, Hôpital de laPitié- Salpétrière, Paris, France; Département de Neurologie, Institut du Cerveau et de la Moelle épinière (ICM), Hôpital de la Pitié-Salpétrière, Paris, France.
10: Department of Pathology, University of Washington, Seattle, WA, USA.
11: Clinical Neurochemistry Laboratory, Department of Neuroscience and Physiology, University of Goteborg, Sahlgrenska University Hospital, Molndal, Sweden.
12: Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
13: Alzheimer's Association, Chicago, IL, USA.
14: Department of Neurology, Mayo Clinic Jacksonville, Jacksonville, FL, USA.
15: Department of Neurodegeneration, Center of Neurology, Section for Dementia Research, Hertie-Institute of Clinical Brain Research, University of Tubingen, Tubingen, Germany.
16: Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
17: Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
18: Department of Epidemiology, Joseph P Mailman School of Public Health, Columbia University, New York, NY, USA.
19: Alzheimer's Disease Cooperative Study, Department of Neurosciences, UCSD School of Medicine, La Jolla, CA, USA.
20: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
21: Meso Scale Discovery, Rockville, MD, USA.
22: Department of Medicine, Radiology and Psychiatry, University of California, San Francisco, CA, USA.
23: Texas Tech University Health Science Center, Garrison Institute on Aging, Lubbock, TX, USA.
24: Pfizer Inc., New York, NY, USA.

Associated clinical trials:

Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly | NCT04265482

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