Distinct subcellular trafficking resulting from monomeric vs multimeric targeting to endothelial ICAM-1: implications for drug delivery.

PubWeight™: 0.76‹?›

🔗 View Article (PMC 4255724)

Published in Mol Pharm on October 24, 2014

Authors

Rasa Ghaffarian1, Silvia Muro

Author Affiliations

1: Fischell Department of Bioengineering, University of Maryland , 2330 Jeong H. Kim Engineering Building, College Park, Maryland 20742, United States.

Articles cited by this

Rab11 regulates recycling through the pericentriolar recycling endosome. J Cell Biol (1996) 9.27

The major human rhinovirus receptor is ICAM-1. Cell (1989) 7.81

Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol (2007) 6.48

Pathways and mechanisms of endocytic recycling. Nat Rev Mol Cell Biol (2009) 5.60

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell (1991) 4.15

Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung. Nat Biotechnol (2007) 3.54

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol (2002) 3.16

Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains. Nat Cell Biol (2006) 3.08

Stimulation-dependent recycling of integrin beta1 regulated by ARF6 and Rab11. Traffic (2004) 2.91

Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodies. J Cell Biol (1982) 2.84

Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature (2003) 2.74

Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin. Mol Biol Cell (2005) 2.74

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment. J Cell Biol (1984) 2.73

Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes. J Cell Biol (1984) 2.71

Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Mol Ther (2008) 2.69

Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells. Circulation (1998) 2.57

Intravascular ultrasound molecular imaging of atheroma components in vivo. J Am Coll Cardiol (2004) 2.45

A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. J Cell Sci (2003) 2.34

Ultrasonic imaging of tumor angiogenesis using contrast microbubbles targeted via the tumor-binding peptide arginine-arginine-leucine. Cancer Res (2005) 2.34

Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. J Cell Biol (1995) 2.02

Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1. J Immunol (2003) 1.95

Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1. J Pharmacol Exp Ther (2006) 1.93

GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps. Mol Biol Cell (2002) 1.82

Multifunctional and stimuli-sensitive pharmaceutical nanocarriers. Eur J Pharm Biopharm (2008) 1.78

Folate-targeted therapies for cancer. J Med Chem (2010) 1.73

ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs. Blood (2004) 1.58

Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium. Arterioscler Thromb Vasc Biol (2012) 1.55

Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress. Am J Physiol Cell Physiol (2003) 1.54

Targeted ultrasound contrast agents: in vitro assessment of endothelial dysfunction and multi-targeting to ICAM-1 and sialyl Lewisx. Biotechnol Bioeng (2005) 1.53

Recycling endosomes. J Cell Sci (2006) 1.48

Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: opportunities and challenges. Mol Pharm (2012) 1.40

Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells. Biorheology (2009) 1.32

PLGA nanoparticle--peptide conjugate effectively targets intercellular cell-adhesion molecule-1. Bioconjug Chem (2007) 1.31

Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis. Mol Ther (2005) 1.29

Delivery of acid sphingomyelinase in normal and niemann-pick disease mice using intercellular adhesion molecule-1-targeted polymer nanocarriers. J Pharmacol Exp Ther (2008) 1.28

ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface. Blood (2003) 1.28

Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers. J Control Release (2010) 1.27

Dynamic partitioning into lipid rafts controls the endo-exocytic cycle of the alphaL/beta2 integrin, LFA-1, during leukocyte chemotaxis. Mol Biol Cell (2005) 1.25

Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. J Control Release (2010) 1.16

ICAM-1: targeted docking for exogenous as well as endogenous ligands. Adv Drug Deliv Rev (2004) 1.14

Demonstration of two distinct transferrin receptor recycling pathways and transferrin-independent receptor internalization in K562 cells. J Biol Chem (1986) 1.13

RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. Blood (2008) 1.13

A phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients. Transplantation (1993) 1.10

Challenges in design and characterization of ligand-targeted drug delivery systems. J Control Release (2012) 1.07

Molecular and cellular mechanisms of receptor-mediated endocytosis. DNA Cell Biol (1991) 1.03

New biotechnological and nanomedicine strategies for treatment of lysosomal storage disorders. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.01

Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1. J Control Release (2011) 1.01

Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders. Nanomedicine (2011) 0.97

Will the polio niche remain vacant? Dev Biol (Basel) (2001) 0.95

Dimerization of the polymeric immunoglobulin receptor controls its transcytotic trafficking. Mol Biol Cell (1998) 0.93

Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor. J Inherit Metab Dis (2012) 0.93

Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells. Biochim Biophys Acta (1999) 0.92

Characterization of endothelial internalization and targeting of antibody-enzyme conjugates in cell cultures and in laboratory animals. Methods Mol Biol (2004) 0.91

Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders. Drug Deliv Transl Res (2012) 0.89

Inflammation-specific T1 imaging using anti-intercellular adhesion molecule 1 antibody-conjugated gadolinium diethylenetriaminepentaacetic acid. Mol Imaging (2007) 0.87

Anti-adhesion molecule therapies in inflammatory bowel disease: touch and go. Autoimmun Rev (2008) 0.84

Self-assembled nanoplatform for targeted delivery of chemotherapy agents via affinity-regulated molecular interactions. Biomaterials (2010) 0.84

Recycling and LFA-1-dependent trafficking of ICAM-1 to the immunological synapse. J Cell Biochem (2010) 0.82

Immunoliposomes that target endothelium in vitro are dependent on lipid raft formation. Mol Pharm (2010) 0.81

A DNA-Device that Mediates Selective Endosomal Escape and Intracellular Delivery of Drugs and Biologicals. Adv Funct Mater (2014) 0.79

A competitive ELISA for the anti-intercellular adhesion molecule-1 (anti-ICAM-1) binding activity of monoclonal antibody R6.5 in serum. J Pharm Biomed Anal (1991) 0.78

A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice. J Pharmacol Exp Ther (2011) 0.78

Articles by these authors

Oxygen microscopy by two-photon-excited phosphorescence. Chemphyschem (2008) 2.17

Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium. Arterioscler Thromb Vasc Biol (2012) 1.55

Advanced drug delivery systems that target the vascular endothelium. Mol Interv (2006) 1.54

Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury. Nat Biotechnol (2003) 1.46

Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells. Biorheology (2009) 1.32

In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium. J Nucl Med (2007) 1.30

Delivery of acid sphingomyelinase in normal and niemann-pick disease mice using intercellular adhesion molecule-1-targeted polymer nanocarriers. J Pharmacol Exp Ther (2008) 1.28

ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface. Blood (2003) 1.28

Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers. J Control Release (2010) 1.27

Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. J Control Release (2010) 1.16

RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. Blood (2008) 1.13

Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes. J Control Release (2008) 1.06

Endothelial targeting of antibody-decorated polymeric filomicelles. ACS Nano (2011) 1.03

Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1. ACS Nano (2012) 1.02

Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1. J Control Release (2011) 1.01

Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders. Nanomedicine (2011) 0.97

Transport of nanocarriers across gastrointestinal epithelial cells by a new transcellular route induced by targeting ICAM-1. J Control Release (2012) 0.97

Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor. J Inherit Metab Dis (2012) 0.93

Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124. Biomaterials (2012) 0.89

Specific binding, uptake, and transport of ICAM-1-targeted nanocarriers across endothelial and subendothelial cell components of the blood-brain barrier. Pharm Res (2014) 0.87

Open challenges in magnetic drug targeting. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2014) 0.84

In vivo performance of polymer nanocarriers dually-targeted to epitopes of the same or different receptors. Biomaterials (2013) 0.83

Biodistribution and endocytosis of ICAM-1-targeting antibodies versus nanocarriers in the gastrointestinal tract in mice. Int J Nanomedicine (2012) 0.83

Biological functionalization of drug delivery carriers to bypass size restrictions of receptor-mediated endocytosis independently from receptor targeting. ACS Nano (2013) 0.82

Models and methods to evaluate transport of drug delivery systems across cellular barriers. J Vis Exp (2013) 0.81

Clathrin-mediated endocytosis is impaired in type A-B Niemann-Pick disease model cells and can be restored by ICAM-1-mediated enzyme replacement. Mol Pharm (2014) 0.79

A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice. J Pharmacol Exp Ther (2011) 0.78

Targeting, endocytosis, and lysosomal delivery of active enzymes to model human neurons by ICAM-1-targeted nanocarriers. Pharm Res (2014) 0.77

Effect of thiol pendant conjugates on plasmid DNA binding, release, and stability of polymeric delivery vectors. Biomacromolecules (2012) 0.76

Enhancing biodistribution of therapeutic enzymes in vivo by modulating surface coating and concentration of ICAM-1-targeted nanocarriers. J Biomed Nanotechnol (2014) 0.75

Effect of Glycocalyx on Drug Delivery Carriers Targeted to Endothelial Cells. Int J Transp Phenom (2011) 0.75

Investigating polymer thiolation in gene delivery. J Biomater Sci Polym Ed (2012) 0.75

Biodegradable "Smart" Polyphosphazenes with Intrinsic Multi-Functionality as Intracellular Protein Delivery Vehicles. Biomacromolecules (2017) 0.75