Published in Front Cell Neurosci on September 30, 2014
Endoplasmic reticulum stress-regulated CXCR3 pathway mediates inflammation and neuronal injury in acute glaucoma. Cell Death Dis (2015) 0.81
Editorial Research Topic "Chemokines and chemokine receptors in brain homeostasis". Front Cell Neurosci (2015) 0.77
TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain. J Neuroinflammation (2016) 0.77
CXCL10 and blood-brain barrier modulation in rabies virus infection. Oncotarget (2016) 0.76
Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance. J Immunol (2016) 0.75
A protective role for IL-1 signaling during mouse adenovirus type 1-induced encephalitis. J Virol (2016) 0.75
CCL2, but not its receptor, is essential to restrict immune privileged central nervous system-invasion of Japanese encephalitis virus via regulating accumulation of CD11b(+) Ly-6C(hi) monocytes. Immunology (2016) 0.75
Identification of a major co-receptor for primary isolates of HIV-1. Nature (1996) 23.81
Global trends in emerging infectious diseases. Nature (2008) 23.66
Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity (2003) 21.56
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature (1996) 20.59
How many drug targets are there? Nat Rev Drug Discov (2006) 14.22
Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol (1999) 13.55
Chemokines: a new classification system and their role in immunity. Immunity (2000) 13.03
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol (2006) 11.06
Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol (2009) 8.67
Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci (2006) 8.25
Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest (2007) 7.02
Epidemic West Nile encephalitis, New York, 1999: results of a household-based seroepidemiological survey. Lancet (2001) 6.49
Epidemiology and transmission dynamics of West Nile virus disease. Emerg Infect Dis (2005) 6.09
Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci U S A (1998) 5.15
Three or more routes for leukocyte migration into the central nervous system. Nat Rev Immunol (2003) 4.76
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A (1999) 4.61
Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov (2004) 4.31
Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands. Immunity (2011) 3.88
Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival. J Virol (2005) 3.59
CCR5 deficiency increases risk of symptomatic West Nile virus infection. J Exp Med (2006) 3.57
Regulation of innate immune responses in the brain. Nat Rev Immunol (2009) 3.41
CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest (2007) 3.39
Estimated global incidence of Japanese encephalitis: a systematic review. Bull World Health Organ (2011) 3.35
Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis. J Virol (2005) 3.31
Pathogenesis of West Nile Virus infection: a balance between virulence, innate and adaptive immunity, and viral evasion. J Virol (2006) 3.15
Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. J Immunol (2001) 3.13
Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection. J Exp Med (2005) 3.08
Ly6c+ "inflammatory monocytes" are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis. J Exp Med (2008) 3.08
The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol (2012) 3.07
The chemokine superfamily revisited. Immunity (2012) 2.83
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. Nat Neurosci (2010) 2.79
CCR5 deficiency is a risk factor for early clinical manifestations of West Nile virus infection but not for viral transmission. J Infect Dis (2010) 2.72
Genetic deficiency of chemokine receptor CCR5 is a strong risk factor for symptomatic West Nile virus infection: a meta-analysis of 4 cohorts in the US epidemic. J Infect Dis (2008) 2.54
CD4+ T-cell responses are required for clearance of West Nile virus from the central nervous system. J Virol (2006) 2.44
The chemokine and chemokine receptor superfamilies and their molecular evolution. Genome Biol (2006) 2.42
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest (2010) 2.38
CD8+ T cells require perforin to clear West Nile virus from infected neurons. J Virol (2006) 2.31
Drug discovery: playing dirty. Nature (2005) 2.12
International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2013) 2.11
Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks. J Cereb Blood Flow Metab (2009) 1.97
A deletion in the chemokine receptor 5 (CCR5) gene is associated with tickborne encephalitis. J Infect Dis (2008) 1.95
Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation. Glia (2000) 1.88
West Nile virus neuroinvasion and encephalitis induced by macrophage depletion in mice. Arch Virol (1996) 1.79
Neutrophil receptors for interleukin-8 and related CXC chemokines. Semin Hematol (1997) 1.78
CCR2 signaling contributes to ischemia-reperfusion injury in kidney. J Am Soc Nephrol (2003) 1.73
G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. Blood (2006) 1.66
The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome. Blood (2011) 1.65
Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences. Hum Mol Genet (1999) 1.65
Chemokine receptor antagonists: overcoming developmental hurdles. Nat Rev Drug Discov (2008) 1.64
Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury. J Neuroimmunol (2002) 1.62
CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. J Immunol (2008) 1.61
Microglia recognize double-stranded RNA via TLR3. J Immunol (2006) 1.60
Pathological expression of CXCL12 at the blood-brain barrier correlates with severity of multiple sclerosis. Am J Pathol (2008) 1.58
Chemokine receptor Ccr2 is critical for monocyte accumulation and survival in West Nile virus encephalitis. J Immunol (2010) 1.58
Control of glial immune function by neurons. Glia (2001) 1.58
West Nile virus in Europe: emergence, epidemiology, diagnosis, treatment, and prevention. Clin Microbiol Infect (2013) 1.58
Different chemokine expression in lethal and non-lethal murine West Nile virus infection. J Med Virol (2004) 1.55
Proinflammatory cytokines and chemokines in humans with Japanese encephalitis. J Infect Dis (2004) 1.48
CSF findings in 250 patients with serologically confirmed West Nile virus meningitis and encephalitis. Neurology (2005) 1.45
Imidazo-pyrazine derivatives as potent CXCR3 antagonists. Bioorg Med Chem Lett (2009) 1.40
The global resurgence of arboviral diseases. Trans R Soc Trop Med Hyg (1996) 1.38
A paradoxical role for neutrophils in the pathogenesis of West Nile virus. J Infect Dis (2010) 1.37
Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling. J Virol (2008) 1.35
CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Res (2012) 1.34
A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum (2011) 1.32
West Nile virus and other arboviral diseases--United States, 2012. MMWR Morb Mortal Wkly Rep (2013) 1.31
A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation. J Pharmacol Exp Ther (2007) 1.30
CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin. J Neuroinflammation (2005) 1.27
Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle. J Biol Chem (2000) 1.24
Host genetic risk factors for West Nile virus infection and disease progression. PLoS One (2011) 1.22
Immunopathological study of spleen during Japanese encephalitis virus infection in mice. Br J Exp Pathol (1988) 1.22
Variable effect on peripheral blood leucocytes during JE virus infection of man. Clin Exp Immunol (1979) 1.21
CCR5: no longer a "good for nothing" gene--chemokine control of West Nile virus infection. Trends Immunol (2006) 1.20
IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis. J Immunol (2004) 1.18
Differential responses of human brain cells to West Nile virus infection. J Neurovirol (2005) 1.17
CCR5 antagonism in HIV infection: current concepts and future opportunities. Annu Rev Med (2011) 1.13
How did chikungunya reach the Indian Ocean? Lancet Infect Dis (2006) 1.13
CD8+ T-cells mediate immunopathology in tick-borne encephalitis. Virology (2008) 1.12
Efficacy of the CCR5 antagonist maraviroc in reducing early, ritonavir-induced atherogenesis and advanced plaque progression in mice. Circulation (2013) 1.11
West Nile virus encephalitis: sequential histopathological and immunological events in a murine model of infection. J Neurovirol (2007) 1.10
Breakdown of blood-brain barrier by virus-induced cytokine during Japanese encephalitis virus infection. Int J Exp Pathol (1992) 1.08
Interferon and interferon-induced chemokine expression is associated with control of acute viremia in West Nile virus-infected blood donors. J Infect Dis (2008) 1.08
CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10. J Virol (2003) 1.08
The severity of murray valley encephalitis in mice is linked to neutrophil infiltration and inducible nitric oxide synthase activity in the central nervous system. J Virol (1999) 1.07
Induction of IP-10 (CXCL10) in astrocytes following Japanese encephalitis. Neurosci Lett (2007) 1.05
CXCR1/2 inhibition enhances pancreatic islet survival after transplantation. J Clin Invest (2012) 1.05
Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist. J Pharmacol Exp Ther (2007) 1.05
Characterization of brain-infiltrating mononuclear cells during infection with mouse hepatitis virus strain JHM. J Neuroimmunol (1991) 1.01
The role of chemokines during viral infection of the CNS. PLoS Pathog (2010) 1.00
IFNs are critical regulators of IL-1 receptor antagonist and IL-1 expression in human microglia. J Immunol (1998) 0.99
Discovery of 2-hydroxy-N,N-dimethyl-3-{2-[[(R)-1-(5- methylfuran-2-yl)propyl]amino]-3,4-dioxocyclobut-1-enylamino}benzamide (SCH 527123): a potent, orally bioavailable CXCR2/CXCR1 receptor antagonist. J Med Chem (2006) 0.99
Cell-intrinsic innate immune control of West Nile virus infection. Trends Immunol (2012) 0.97
Maraviroc, a CCR5 antagonist, prevents development of hepatocellular carcinoma in a mouse model. PLoS One (2013) 0.96
Secretion of the chemokine interleukin-8 during Japanese encephalitis virus infection. J Med Microbiol (2000) 0.96
Japanese encephalitis virus infection induces changes of mRNA profile of mouse spleen and brain. Virol J (2011) 0.93
Transcriptomic profile of host response in Japanese encephalitis virus infection. Virol J (2011) 0.92
Genetic variants and susceptibility to neurological complications following West Nile virus infection. J Infect Dis (2011) 0.92
Acute flaccid paralysis as an unusual presenting symptom of Japanese encephalitis: a case report and review of the literature. Infection (2007) 0.92
TNF-alpha-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis. J Neuroimmunol (2010) 0.91