G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism.

PubWeight™: 1.66‹?› | Rank: Top 3%

🔗 View Article (PMC 1895560)

Published in Blood on May 30, 2006

Authors

Benjamin J Capoccia1, Rebecca M Shepherd, Daniel C Link

Author Affiliations

1: Division of Oncology, Washington University School of Medicine, Box 8007, 660 South Euclid Ave, St Louis, MO 63110, USA.

Articles citing this

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest (2010) 3.74

Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell (2008) 3.56

The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis. Trends Immunol (2007) 3.25

Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells (2008) 3.12

Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect. Bone (2012) 2.24

CXCR4 blockade augments bone marrow progenitor cell recruitment to the neovasculature and reduces mortality after myocardial infarction. Proc Natl Acad Sci U S A (2010) 1.61

Chemokine receptor Ccr2 is critical for monocyte accumulation and survival in West Nile virus encephalitis. J Immunol (2010) 1.58

Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J Clin Invest (2010) 1.55

Diabetes Limits Stem Cell Mobilization Following G-CSF but Not Plerixafor. Diabetes (2015) 1.47

Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4. Leukemia (2011) 1.44

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood (2009) 1.40

Widespread nonhematopoietic tissue distribution by transplanted human progenitor cells with high aldehyde dehydrogenase activity. Stem Cells (2007) 1.30

Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. J Leukoc Biol (2008) 1.20

Spatial and temporal coordination of bone marrow-derived cell activity during arteriogenesis: regulation of the endogenous response and therapeutic implications. Microcirculation (2010) 1.15

Integrins and bone metastasis: integrating tumor cell and stromal cell interactions. Bone (2010) 1.09

Stromal-derived factor-1[alpha] correlates with circulating endothelial progenitor cells and with acute lesion volume in stroke patients. Stroke (2011) 1.01

A review on angiogenesis and its assays. Iran J Basic Med Sci (2012) 1.00

Angiogenesis in eye disease: immunity gained or immunity lost? Semin Immunopathol (2008) 1.00

Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice. Respir Res (2007) 0.99

Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4). J Med Chem (2011) 0.98

Chemokine receptors as important regulators of pathogenesis during arboviral encephalitis. Front Cell Neurosci (2014) 0.97

The CXCR4/CXCL12 (SDF-1) signalling pathway protects non-obese diabetic mouse from autoimmune diabetes. Clin Exp Immunol (2007) 0.97

Chemokine control of West Nile virus infection. Exp Cell Res (2011) 0.95

Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth. Am J Physiol Heart Circ Physiol (2009) 0.94

A novel CXCR4 antagonist derived from human SDF-1beta enhances angiogenesis in ischaemic mice. Cardiovasc Res (2009) 0.93

A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. BMC Genet (2008) 0.91

Hematopoietic cytokines for cardiac repair: mobilization of bone marrow cells and beyond. Basic Res Cardiol (2011) 0.91

Macrophages in collateral arteriogenesis. Front Physiol (2012) 0.90

Progenitors in motion: mechanisms of mobilization of endothelial progenitor cells. Br J Clin Pharmacol (2009) 0.89

In situ tissue regeneration through host stem cell recruitment. Exp Mol Med (2013) 0.87

Bone marrow endothelial progenitors augment atherosclerotic plaque regression in a mouse model of plasma lipid lowering. Stem Cells (2012) 0.87

Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes. J Leukoc Biol (2010) 0.86

Cell biology and clinical promise of G-CSF: immunomodulation and neuroprotection. J Cell Mol Med (2008) 0.86

Physiology and pharmacology of plerixafor. Transfus Med Hemother (2013) 0.85

Granulocyte colony-stimulating factor (G-CSF) depresses angiogenesis in vivo and in vitro: implications for sourcing cells for vascular regeneration therapy. J Thromb Haemost (2010) 0.85

Differential Roles of Chemokines CCL2 and CCL7 in Monocytosis and Leukocyte Migration during West Nile Virus Infection. J Immunol (2015) 0.83

Bone marrow-derived CXCR4+ cells mobilized by macrophage colony-stimulating factor participate in the reduction of infarct area and improvement of cardiac remodeling after myocardial infarction in mice. Am J Pathol (2007) 0.83

Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration. Blood (2010) 0.81

Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications. J Vasc Res (2013) 0.81

Challenges in the translation of cardiovascular cell therapy. J Nucl Med (2010) 0.79

A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment. Sci Rep (2014) 0.79

Fucoidan Stimulates Monocyte Migration via ERK/p38 Signaling Pathways and MMP9 Secretion. Mar Drugs (2015) 0.78

Impaired compensation to femoral artery ligation in diet-induced obese mice is primarily mediated via suppression of collateral growth by Nox2 and p47phox. Am J Physiol Heart Circ Physiol (2015) 0.78

[(18)F]DPA-714 PET imaging of AMD3100 treatment in a mouse model of stroke. Mol Pharm (2014) 0.78

Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells. Am J Physiol Heart Circ Physiol (2014) 0.77

Cellular therapy for repair of cardiac damage after acute myocardial infarction. Int J Cell Biol (2009) 0.77

Noninvasive tracking of gene transcript and neuroprotection after gene therapy. Gene Ther (2015) 0.77

Impaired Mobilization of Vascular Reparative Bone Marrow Cells in Streptozotocin-Induced Diabetes but not in Leptin Receptor-Deficient db/db Mice. Sci Rep (2016) 0.76

Strategy to Prime the Host and Cells to Augment Therapeutic Efficacy of Progenitor Cells for Patients with Myocardial Infarction. Front Cardiovasc Med (2016) 0.75

Retention of stemness and vasculogenic potential of human umbilical cord blood stem cells after repeated expansions on PES-nanofiber matrices. Biomaterials (2014) 0.75

Combinatorial G-CSF/AMD3100 treatment in cardiac repair after myocardial infarction. PLoS One (2014) 0.75

Effect of Periodic Granulocyte Colony-Stimulating Factor Administration on Endothelial Progenitor Cells and Different Monocyte Subsets in Pediatric Patients with Muscular Dystrophies. Stem Cells Int (2015) 0.75

Novel method to assess arterial insufficiency in rodent hind limb. J Surg Res (2015) 0.75

Point-of-Care Rapid-Seeding Ventricular Assist Device with Blood-Derived Endothelial Cells to Create a Living Antithrombotic Coating. ASAIO J (2016) 0.75

Circulating fibrocyte mobilization in negative pressure wound therapy. J Cell Mol Med (2017) 0.75

Articles cited by this

Isolation of putative progenitor endothelial cells for angiogenesis. Science (1997) 30.27

Mechanisms of angiogenesis and arteriogenesis. Nat Med (2000) 13.88

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res (1999) 11.32

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med (1999) 10.16

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med (2001) 9.53

VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell (2006) 9.32

Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors. Circulation (2003) 7.29

Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci U S A (2001) 7.19

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med (2005) 7.01

Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A (2000) 6.59

Evidence for circulating bone marrow-derived endothelial cells. Blood (1998) 6.15

VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest (2004) 5.59

Mouse model of angiogenesis. Am J Pathol (1998) 4.28

Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation (2001) 4.01

Universal GFP reporter for the study of vascular development. Genesis (2000) 3.97

Bone marrow-derived cells do not incorporate into the adult growing vasculature. Circ Res (2003) 3.81

Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation. Circ Res (2000) 3.64

Monocyte activation in angiogenesis and collateral growth in the rabbit hindlimb. J Clin Invest (1998) 3.34

Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells. Circ Res (2001) 3.30

Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J Exp Med (2001) 3.25

Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity (1996) 2.95

Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. Circulation (2002) 2.84

Granulocyte colony-stimulating factor mobilizes functional endothelial progenitor cells in patients with coronary artery disease. Arterioscler Thromb Vasc Biol (2004) 2.65

G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med (2005) 2.64

Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells. Circulation (2003) 2.52

Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation (2003) 2.27

Blood monocyte concentration is critical for enhancement of collateral artery growth. Am J Physiol Heart Circ Physiol (2002) 1.99

Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Circulation (2001) 1.92

Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines. Circulation (2004) 1.92

Mobilizing endothelial progenitor cells. Hypertension (2005) 1.84

Endothelial-like cells derived from human CD14 positive monocytes. Differentiation (2000) 1.73

Levels of serum granulocyte colony-stimulating factor in patients with infections. Blood (1990) 1.71

Expression of the G-CSF receptor on hematopoietic progenitor cells is not required for their mobilization by G-CSF. Blood (2000) 1.66

Impaired collateral vessel development associated with reduced expression of vascular endothelial growth factor in ApoE-/- mice. Circulation (1999) 1.66

Retracted Angiogenesis by implantation of peripheral blood mononuclear cells and platelets into ischemic limbs. Circulation (2002) 1.65

Impaired arteriogenic response to acute hindlimb ischemia in CD4-knockout mice. Circulation (2003) 1.63

Purification and characterization of the receptor for murine granulocyte colony-stimulating factor. J Biol Chem (1990) 1.60

Determination of bone marrow-derived endothelial progenitor cell significance in angiogenic growth factor-induced neovascularization in vivo. Exp Hematol (2002) 1.49

Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries. Circulation (2004) 1.46

Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment. Circulation (2004) 1.44

Placental growth factor (PlGF) and its receptor Flt-1 (VEGFR-1): novel therapeutic targets for angiogenic disorders. Ann N Y Acad Sci (2002) 1.33

Temporal patterns of gene expression after acute hindlimb ischemia in mice: insights into the genomic program for collateral vessel development. J Am Coll Cardiol (2004) 1.12

Utilizing granulocyte colony-stimulating factor to enhance vascular graft endothelialization from circulating blood cells. Ann Vasc Surg (2002) 0.91

Analysis of origin and optimization of expansion and transduction of circulating peripheral blood endothelial progenitor cells in the rhesus macaque model. Hum Gene Ther (2002) 0.90

Proliferative and migratory responses of murine microvascular endothelial cells to granulocyte-colony-stimulating factor. J Cell Physiol (1993) 0.90

CD11b-mediated migratory property of peripheral blood B cells. J Allergy Clin Immunol (2005) 0.89

Breast tumor cell soluble factors induce monocytes to produce angiogenic but not angiostatic CXC chemokines. Int J Cancer (2005) 0.83

Whole bone marrow transplantation induces angiogenesis following acute ischemia. Redox Rep (2002) 0.81

CD34+ cells homing: quantitative expression of adhesion molecules and adhesion of CD34+ cells to endothelial cells exposed to shear stress. Biorheology (2003) 0.81

Articles by these authors

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature (2008) 38.13

Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med (2009) 33.09

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature (2012) 14.33

DNMT3A mutations in acute myeloid leukemia. N Engl J Med (2010) 14.07

The origin and evolution of mutations in acute myeloid leukemia. Cell (2012) 9.66

Clonal architecture of secondary acute myeloid leukemia. N Engl J Med (2012) 6.71

Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci U S A (2009) 4.17

Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. JAMA (2011) 4.11

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature (2013) 4.04

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet (2011) 4.02

Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood (2008) 3.89

G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood (2005) 3.76

The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. J Am Coll Cardiol (2006) 3.17

Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction. Blood (2008) 3.11

G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood. Immunity (2002) 2.72

High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples. J Clin Invest (2009) 2.66

CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest (2010) 2.38

Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. Blood (2009) 2.25

STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood (2006) 2.12

Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood (2004) 2.01

Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. J Exp Med (2011) 1.96

Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. Blood (2007) 1.92

Regulation of neutrophil homeostasis. Curr Opin Hematol (2007) 1.87

CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions. Blood (2009) 1.83

Next-generation sequencing identifies the natural killer cell microRNA transcriptome. Genome Res (2010) 1.75

A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A (2003) 1.69

Prevalence of mutations in ELANE, GFI1, HAX1, SBDS, WAS and G6PC3 in patients with severe congenital neutropenia. Br J Haematol (2009) 1.59

Mutations of the SBDS gene are present in most patients with Shwachman-Diamond syndrome. Blood (2004) 1.58

A mouse-based strategy for cyclophosphamide pharmacogenomic discovery. J Appl Physiol (1985) (2003) 1.55

Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood (2007) 1.55

Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor. Curr Opin Hematol (2002) 1.48

Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway. Blood (2003) 1.44

Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation. J Bone Miner Res (2008) 1.42

Genomics of AML: clinical applications of next-generation sequencing. Hematology Am Soc Hematol Educ Program (2011) 1.41

Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5. J Clin Invest (2008) 1.41

Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity. Blood (2009) 1.40

The many causes of severe congenital neutropenia. N Engl J Med (2009) 1.40

Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia. Br J Haematol (2007) 1.37

N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood (2012) 1.33

Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100. Blood (2006) 1.29

Lentiviral-mediated RNAi inhibition of Sbds in murine hematopoietic progenitors impairs their hematopoietic potential. Blood (2007) 1.25

Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells. J Biol Chem (2006) 1.23

Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. J Leukoc Biol (2008) 1.20

Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Res (2009) 1.20

Commonly dysregulated genes in murine APL cells. Blood (2006) 1.18

Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol (2010) 1.17

A truncation mutant of Csf3r cooperates with PML-RARα to induce acute myeloid leukemia in mice. Exp Hematol (2011) 1.17

Regulation of hematopoietic stem cell activity by inflammation. Front Immunol (2013) 1.17

Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood (2010) 1.16

Mice expressing a neutrophil elastase mutation derived from patients with severe congenital neutropenia have normal granulopoiesis. Blood (2002) 1.09

Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis. Blood (2006) 1.07

Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection. Blood (2006) 1.06

Regulation of neutrophil trafficking from the bone marrow. Cell Mol Life Sci (2011) 1.03

Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunol Immunother (2014) 0.96

Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane. Blood (2011) 0.93

Dicer and outcomes in patients with acute myeloid leukemia (AML). Leuk Res (2009) 0.91

Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis. Blood (2011) 0.90

Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function. Blood (2012) 0.90

Inherited bone marrow failure syndromes in adolescents and young adults. Ann Med (2014) 0.88

Severe congenital neutropenia and the unfolded protein response. Curr Opin Hematol (2008) 0.87

Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes. J Leukoc Biol (2010) 0.86

The diversity of mutations and clinical outcomes for ELANE-associated neutropenia. Curr Opin Hematol (2015) 0.86

Niche competition and cancer metastasis to bone. J Clin Invest (2011) 0.85

Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon. Blood (2013) 0.84

Cellular complexity of the bone marrow hematopoietic stem cell niche. Calcif Tissue Int (2013) 0.80

5. Mechanisms of disordered granulopoiesis in congenital neutropenia. Curr Top Dev Biol (2006) 0.79

Enhancing hematopoietic growth factor performance. Nat Med (2012) 0.78

p120 nucleolar-proliferating antigen is a direct target of G-CSF signaling during myeloid differentiation. J Leukoc Biol (2006) 0.77

CXCR2 is the Tpo of the iceberg. Blood (2011) 0.76

Divergent pathways in COS-7 cells mediate defective internalization and intracellular routing of truncated G-CSFR forms in SCN/AML. PLoS One (2008) 0.76

Neutrophil differentiation. Haematologica (2005) 0.75

A comparison of cyclic neutropenia in childhood and severe congenital neutropenia. Haematologica (2005) 0.75