Published in Biotechnol Bioeng on November 24, 2014
Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10. Malar J (2015) 0.86
Protein stability: a crystallographer's perspective. Acta Crystallogr F Struct Biol Commun (2016) 0.81
Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail. Malar J (2016) 0.78
Improvement of a fermentation process for the production of two PfAMA1-DiCo-based malaria vaccine candidates in Pichia pastoris. Sci Rep (2017) 0.75
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci U S A (2005) 3.75
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic (2007) 3.01
A transcriptional network in polycystic kidney disease. EMBO J (2004) 2.21
Uptake of a fluorescent marker in plant cells is sensitive to brefeldin A and wortmannin. Plant Cell (2002) 1.83
Plant-derived pharmaceuticals--the road forward. Trends Plant Sci (2005) 1.82
Molecular farming in plants: host systems and expression technology. Trends Biotechnol (2003) 1.78
Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes. Proc Natl Acad Sci U S A (2008) 1.74
GMP issues for recombinant plant-derived pharmaceutical proteins. Biotechnol Adv (2011) 1.64
Plant-based production of biopharmaceuticals. Curr Opin Plant Biol (2004) 1.60
Fusion proteins comprising a Fusarium-specific antibody linked to antifungal peptides protect plants against a fungal pathogen. Nat Biotechnol (2004) 1.59
Emphysematous gastritis caused by Sarcina ventriculi. Gastrointest Endosc (2010) 1.54
Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants. EMBO Rep (2005) 1.45
Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression. Genes Dev (2007) 1.45
Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production. Metab Eng (2008) 1.39
A versatile toolkit to produce sensitive FRET biosensors to visualize signaling in time and space. Sci Signal (2013) 1.37
Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth. Genes Dev (2004) 1.30
Plant cell cultures for the production of recombinant proteins. Nat Biotechnol (2004) 1.27
Sowing the seeds of success: pharmaceutical proteins from plants. Curr Opin Biotechnol (2005) 1.26
The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation. EMBO J (2005) 1.23
Unexpected deposition patterns of recombinant proteins in post-endoplasmic reticulum compartments of wheat endosperm. Plant Physiol (2004) 1.22
Simultaneous occurrence of Hodgkin's lymphoma and eosinophilic granuloma: a potential pitfall in positron emission tomography imaging. Clin Lymphoma (2002) 1.21
Genetic determinants of Pseudomonas aeruginosa biofilm establishment. Microbiology (2009) 1.19
Preliminary X-ray analysis of a human V(H) fragment at 1.8 A resolution. Acta Crystallogr D Biol Crystallogr (2004) 1.18
Evolution of a regulatory framework for pharmaceuticals derived from genetically modified plants. Trends Biotechnol (2008) 1.18
Transgenic plants in the biopharmaceutical market. Expert Opin Emerg Drugs (2005) 1.18
Endosperm-specific co-expression of recombinant soybean ferritin and Aspergillus phytase in maize results in significant increases in the levels of bioavailable iron. Plant Mol Biol (2005) 1.17
The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site. Antimicrob Agents Chemother (2009) 1.14
Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans. Plant Biotechnol J (2007) 1.13
Polyphenoloxidase silencing affects latex coagulation in Taraxacum species. Plant Physiol (2009) 1.11
Potato virus X as a novel platform for potential biomedical applications. Nano Lett (2010) 1.08
Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon. Vaccine (2010) 1.07
Spatial and temporal regulation of the forisome gene for1 in the phloem during plant development. Plant Mol Biol (2007) 1.06
A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children. PLoS One (2011) 1.06
An unusual internal ribosomal entry site of inverted symmetry directs expression of a potato leafroll polerovirus replication-associated protein. Proc Natl Acad Sci U S A (2003) 1.06
Biochemical and functional characterization of anti-HIV antibody-ELP fusion proteins from transgenic plants. Plant Biotechnol J (2008) 1.05
Rapid detection of Pfcrt and Pfmdr1 mutations in Plasmodium falciparum isolates by FRET and in vivo response to chloroquine among children from Osogbo, Nigeria. Malar J (2007) 1.05
Induction of Plasmodium falciparum-specific CD4+ T cells and memory B cells in Gabonese children vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D). PLoS One (2011) 1.04
The potential of plant virus vectors for vaccine production. Drugs R D (2006) 1.03
Granzyme B-H22(scFv), a human immunotoxin targeting CD64 in acute myeloid leukemia of monocytic subtypes. Mol Cancer Ther (2008) 1.03
Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytes. Cell Microbiol (2014) 1.02
Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization. J Cell Sci (2005) 1.01
Plant molecular pharming for the treatment of chronic and infectious diseases. Annu Rev Plant Biol (2014) 1.00
Characterization of rubber particles and rubber chain elongation in Taraxacum koksaghyz. BMC Biochem (2010) 1.00
Molecular farming of pharmaceutical proteins using plant suspension cell and tissue cultures. Curr Pharm Des (2013) 1.00
Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis. J Biol Chem (2005) 1.00
Cellulases for biomass degradation: comparing recombinant cellulase expression platforms. Trends Biotechnol (2013) 0.99
Development of viral nanoparticles for efficient intracellular delivery. Nanoscale (2012) 0.99
Chirped arrays of refractive ellipsoidal microlenses for aberration correction under oblique incidence. Opt Express (2005) 0.99
Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut. Cell Res (2010) 0.98
Influence of elastin-like peptide fusions on the quantity and quality of a tobacco-derived human immunodeficiency virus-neutralizing antibody. Plant Biotechnol J (2009) 0.98
Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems. PLoS One (2013) 0.98
Rapid transient production in plants by replicating and non-replicating vectors yields high quality functional anti-HIV antibody. PLoS One (2010) 0.98
Genomic mining for novel FADH₂-dependent halogenases in marine sponge-associated microbial consortia. Mar Biotechnol (NY) (2012) 0.97
Commercial aspects of pharmaceutical protein production in plants. Curr Pharm Des (2013) 0.97
Proteins from the FLOWERING LOCUS T-like subclade of the PEBP family act antagonistically to regulate floral initiation in tobacco. Plant J (2012) 0.97
Recombinant anti-hCG antibodies retained in the endoplasmic reticulum of transformed plants lack core-xylose and core-alpha(1,3)-fucose residues. Plant Biotechnol J (2004) 0.97
Opportunities for recombinant antigen and antibody expression in transgenic plants--technology assessment. Vaccine (2005) 0.97
Functional analysis of the broadly neutralizing human anti-HIV-1 antibody 2F5 produced in transgenic BY-2 suspension cultures. FASEB J (2007) 0.97
Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting. Plant Biotechnol J (2012) 0.97
Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V. Proc Natl Acad Sci U S A (2007) 0.96
Plantibodies: applications, advantages and bottlenecks. Curr Opin Biotechnol (2002) 0.96
Viroid-induced RNA silencing of GFP-viroid fusion transgenes does not induce extensive spreading of methylation or transitive silencing. Plant J (2004) 0.96
Plasmodia express two threonine-peptidase complexes during asexual development. Mol Biochem Parasitol (2006) 0.96
The intracellular fate of a recombinant protein is tissue dependent. Plant Physiol (2006) 0.96
A CD14 domain with lipopolysaccharide-binding and -neutralizing activity. Chembiochem (2006) 0.95
Production of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAalpha1) in tobacco is hampered by proteolysis. Biotechnol Bioeng (2005) 0.95
With or without sugar? (A)glycosylation of therapeutic antibodies. Mol Biotechnol (2013) 0.95
Restrictive cardiomyopathy in a patient with primary hyperoxaluria type II. Clin Res Cardiol (2006) 0.94
Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity. Biol Lett (2011) 0.94
Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits. Plant Biotechnol J (2014) 0.94
Small cleavable adapters enhance the specific cytotoxicity of a humanized immunotoxin directed against CD64-positive cells. J Immunother (2008) 0.94
A recombinant multimeric immunoglobulin expressed in rice shows assembly-dependent subcellular localization in endosperm cells. Plant Biotechnol J (2005) 0.93
Malaria parasites co-opt human factor H to prevent complement-mediated lysis in the mosquito midgut. Cell Host Microbe (2013) 0.93
A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency. J Biol Chem (2009) 0.92
Optimizing the yield of recombinant pharmaceutical proteins in plants. Curr Pharm Des (2013) 0.92
Isolation and characterization of isochorismate synthase and cinnamate 4-hydroxylase during salinity stress, wounding, and salicylic acid treatment in Carthamus tinctorius. Plant Signal Behav (2013) 0.92
Flow cytometry-based ultra-high-throughput screening assay for cellulase activity. Anal Biochem (2012) 0.91
Optimization of BY-2 cell suspension culture medium for the production of a human antibody using a combination of fractional factorial designs and the response surface method. Plant Biotechnol J (2013) 0.91
Histone acetylation mediates epigenetic regulation of transcriptional reprogramming in insects during metamorphosis, wounding and infection. Front Zool (2012) 0.90
Cystic kidney diseases: learning from animal models. Nephrol Dial Transplant (2004) 0.90
Ini1/hSNF5 is dispensable for retrovirus-induced cytoplasmic accumulation of PML and does not interfere with integration. FEBS Lett (2004) 0.90
Recombinant CD64-specific single chain immunotoxin exhibits specific cytotoxicity against acute myeloid leukemia cells. Cancer Res (2003) 0.90
Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor. Biotechnol Bioeng (2014) 0.89