Published in Int J Clin Exp Pathol on August 15, 2014
High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting. PLoS One (2015) 0.78
HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer. Cancer Gene Ther (2015) 0.78
Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis. Oncotarget (2016) 0.78
Prognostic value of MMP9 activity level in resected stage I B lung adenocarcinoma. Cancer Med (2016) 0.76
Cadmium attenuates the macrophage response to LPS through inhibition of the NF-κB pathway. Am J Physiol Lung Cell Mol Physiol (2016) 0.76
Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability. Chin Med (2016) 0.75
Low extracellular lysyl oxidase expression is associated with poor prognosis in patients with prostate cancer. Oncol Lett (2016) 0.75
FGFR3 silencing by siRNA inhibits invasion of A549 cells. Oncol Lett (2016) 0.75
Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin (2011) 30.81
Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin (2012) 14.47
Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell (2009) 14.40
Matrix metalloproteinases: regulators of the tumor microenvironment. Cell (2010) 12.90
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell (2009) 6.66
The extracellular matrix: a dynamic niche in cancer progression. J Cell Biol (2012) 6.07
Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell. J Cell Biochem (2003) 4.58
Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. Br J Cancer (2001) 3.10
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech (2011) 2.97
Paradoxical roles for lysyl oxidases in cancer--a prospect. J Cell Biochem (2007) 2.30
The rationale for targeting the LOX family in cancer. Nat Rev Cancer (2012) 2.02
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. J Mol Med (Berl) (2012) 1.67
The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. J Biol Chem (2004) 1.47
LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. Proc Natl Acad Sci U S A (2010) 1.40
Lysyl oxidase as a potential therapeutic target. Drug News Perspect (2008) 1.40
Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways. Int J Cancer (2004) 1.37
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer. J Natl Cancer Inst (2011) 1.34
Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells. Cancer Res (2007) 1.31
Lysyl oxidases in mammalian development and certain pathological conditions. Histol Histopathol (2009) 1.28
Lysyl oxidase expression is an independent marker of prognosis and a predictor of lymph node metastasis in oral and oropharyngeal squamous cell carcinoma (OSCC). Int J Cancer (2010) 1.04
Hypoxia inducible factor 1α-mediated LOX expression correlates with migration and invasion in epithelial ovarian cancer. Int J Oncol (2013) 0.97
Lysyl oxidase: a lung adenocarcinoma biomarker of invasion and survival. Cancer (2010) 0.96
The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model. Clin Cancer Res (2006) 0.96
Down-regulation of lysyl oxidase-induced tumorigenic transformation in NRK-49F cells characterized by constitutive activation of ras proto-oncogene. J Biol Chem (2001) 0.95
Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy. Curr Cancer Drug Targets (2013) 0.92
Expression and significance of hypoxia inducible factor-1α and lysyl oxidase in non-small cell lung cancer. Asian Pac J Cancer Prev (2013) 0.87
Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma. Ann Surg Oncol (2009) 0.86
Targeting the microenvironment. Leuk Lymphoma (2010) 0.85
Upregulated expression of LOX is a novel independent prognostic marker of worse outcome in gastric cancer patients after curative surgery. Oncol Lett (2012) 0.83
Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep (2012) 0.82