Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMC 4212976)

Published in PLoS One on October 29, 2014

Authors

Elisa Coluzzi1, Monica Colamartino1, Renata Cozzi1, Stefano Leone1, Carlo Meneghini1, Nathan O'Callaghan2, Antonella Sgura1

Author Affiliations

1: Department of Science, University of "Roma Tre", Rome, Italy.
2: CSIRO Food and nutritional Sciences, Nutritional Genomics Laboratory, Adelaide, Australia.

Articles citing this

Stress and biological aging: A double-edged sword. Z Gerontol Geriatr (2015) 0.92

Pesticide Use and Relative Leukocyte Telomere Length in the Agricultural Health Study. PLoS One (2015) 0.85

Mesenchymal stem cells-based therapy as a potential treatment in neurodegenerative disorders: is the escape from senescence an answer? Neural Regen Res (2015) 0.83

Transgenerational Developmental Programming of Ovarian Reserve. Sci Rep (2015) 0.81

Telomeric aging: mitotic clock or stress indicator? Front Genet (2015) 0.78

Telomere Length in Peripheral Blood Leukocytes Is Associated with Severity of Biliary Atresia. PLoS One (2015) 0.77

Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage. ACS Chem Biol (2015) 0.76

Transient ALT activation protects human primary cells from chromosome instability induced by low chronic oxidative stress. Sci Rep (2017) 0.75

Mild oxidative stress is beneficial for sperm telomere length maintenance. World J Methodol (2016) 0.75

Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage. Nucleic Acids Res (2017) 0.75

Regular exercise participation improves genomic stability in diabetic patients: an exploratory study to analyse telomere length and DNA damage. Sci Rep (2017) 0.75

Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers. Oncotarget (2016) 0.75

Semen preparation methods and sperm telomere length: density gradient centrifugation versus the swim up procedure. Sci Rep (2016) 0.75

Improvement of gamete quality by stimulating and feeding the endogenous antioxidant system: mechanisms, clinical results, insights on gene-environment interactions and the role of diet. J Assist Reprod Genet (2016) 0.75

Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia. Neuropsychiatr Dis Treat (2015) 0.75

Architecture in 3D cell culture: An essential feature for in vitro toxicology. Toxicol In Vitro (2017) 0.75

Longer Telomere Length and its Association with Lower Levels of C-Peptide. Front Endocrinol (Lausanne) (2017) 0.75

Articles cited by this

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell (1985) 24.17

A DNA damage checkpoint response in telomere-initiated senescence. Nature (2003) 12.55

A survey of telomerase activity in human cancer. Eur J Cancer (1997) 10.84

Oxidative stress shortens telomeres. Trends Biochem Sci (2002) 9.48

Telomere loss: mitotic clock or genetic time bomb? Mutat Res (1992) 6.50

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2. Science (1999) 5.89

The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol (2004) 5.57

Radical causes of cancer. Nat Rev Cancer (2003) 5.45

Protection of mammalian telomeres. Oncogene (2002) 5.38

The in vitro micronucleus technique. Mutat Res (2000) 5.22

Oxyradicals and DNA damage. Carcinogenesis (2000) 4.87

The age of cancer. Nature (2000) 4.32

Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet (1993) 3.96

Alternative lengthening of telomeres in mammalian cells. Oncogene (2002) 3.48

DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett (1991) 3.33

Telomere dynamics in an immortal human cell line. EMBO J (1994) 3.22

Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci U S A (2001) 2.91

Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells. Mutagenesis (2011) 2.66

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts. Free Radic Biol Med (2000) 2.19

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts. Exp Cell Res (1998) 2.09

Role of oxidative stress in telomere length regulation and replicative senescence. Ann N Y Acad Sci (2000) 1.97

Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis (1993) 1.92

A quantitative real-time PCR method for absolute telomere length. Biotechniques (2008) 1.77

Telomere dysfunction and the initiation of genome instability. Nat Rev Cancer (2003) 1.69

Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening. FEBS Lett (1999) 1.69

Telomeres, chromosome instability and cancer. Nucleic Acids Res (2006) 1.67

SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity. Nucleic Acids Res (2003) 1.59

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2. Nucleic Acids Res (2005) 1.59

DNA damage and repair in telomeres: relation to aging. Proc Natl Acad Sci U S A (1995) 1.56

Mitochondrial dysfunction leads to telomere attrition and genomic instability. Aging Cell (2002) 1.44

Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies. Mutat Res (2010) 1.41

Telomeres. Trends Biochem Sci (1991) 1.38

Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening. Biochemistry (2001) 1.32

Accelerated telomere shortening in fibroblasts after extended periods of confluency. Free Radic Biol Med (1998) 1.25

Telomere length mediates the effects of telomerase on the cellular response to genotoxic stress. Exp Cell Res (2004) 1.24

Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema. Am J Physiol Lung Cell Mol Physiol (2006) 1.19

Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1. DNA Repair (Amst) (2010) 1.17

Quantifying telomere lengths of human individual chromosome arms by centromere-calibrated fluorescence in situ hybridization and digital imaging. Am J Pathol (2003) 1.14

Oxidative stress contributes to arsenic-induced telomere attrition, chromosome instability, and apoptosis. J Biol Chem (2003) 1.14

Molecular manifestations and molecular determinants of telomere capping. Cold Spring Harb Symp Quant Biol (2000) 1.12

Micronuclei, nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakage-fusion-bridge cycles in the cytokinesis-block micronucleus assay. Mutat Res (2002) 1.04

Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei. Mutat Res (2000) 1.02

The roles of telomeres and telomerase in cell life span. Mutat Res (1996) 1.01

Telomere length as a marker of oxidative stress in primary human fibroblast cultures. Ann N Y Acad Sci (2000) 1.01

Advanced telomere shortening in respiratory chain disorders. Hum Mol Genet (1997) 0.96

Telomere length measurement by Q-FISH. Methods Cell Sci (2001) 0.91

Aneuploidy, centrosome activity and chromosome instability in cells deficient in homologous recombination repair. Mutat Res (2002) 0.91

A simple method for simultaneous interphase-metaphase chromosome analysis in biodosimetry. Int J Radiat Biol (1998) 0.89

A qPCR-based assay to quantify oxidized guanine and other FPG-sensitive base lesions within telomeric DNA. Biotechniques (2011) 0.86

Transient activation of the ALT pathway in human primary fibroblasts exposed to high-LET radiation. Radiat Res (2010) 0.86

Telomere length measurement in mouse chromosomes by a modified Q-FISH method. Cytogenet Genome Res (2004) 0.82

Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress. J Cell Mol Med (2009) 0.81

The Comet assay for the detection of DNA damage in Mus spretus from Doñana National Park. Environ Res (2003) 0.80

Mitotic non-disjunction as a mechanism for in vitro aneuploidy induction by X-rays in primary human cells. Mutagenesis (1996) 0.79

Possible mechanism of oxygen radical production by human eosinophils mediated by K+ channel activation. Eur J Pharmacol (1995) 0.79

The role of telomere length modulation in delayed chromosome instability induced by ionizing radiation in human primary fibroblasts. Environ Mol Mutagen (2013) 0.78