Published in Nat Biotechnol on November 02, 2014
Modeling the course of amyotrophic lateral sclerosis. Nat Biotechnol (2015) 1.44
DREAMing of benchmarks. Nat Biotechnol (2015) 0.89
Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease1. J Parkinsons Dis (2015) 0.88
Being PRO-ACTive: What can a Clinical Trial Database Reveal About ALS? Neurotherapeutics (2015) 0.86
Data- and knowledge-based modeling of gene regulatory networks: an update. EXCLI J (2015) 0.85
Defining Glomerular Disease in Mechanistic Terms: Implementing an Integrative Biology Approach in Nephrology. Clin J Am Soc Nephrol (2016) 0.82
Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials. Neurology (2016) 0.82
The ALSFRS as an outcome measure in therapeutic trials and its relationship to symptom onset. Amyotroph Lateral Scler Frontotemporal Degener (2016) 0.82
The Role of Big Data in the Management of Sleep-Disordered Breathing. Sleep Med Clin (2016) 0.81
Challenges: Crowdsourced solutions. Nature (2016) 0.78
Urate as a Marker of Risk and Progression of Neurodegenerative Disease. Neurotherapeutics (2016) 0.78
A Crowdsourcing Approach to Developing and Assessing Prediction Algorithms for AML Prognosis. PLoS Comput Biol (2016) 0.78
DREAMTools: a Python package for scoring collaborative challenges. F1000Res (2015) 0.77
A review of disease progression models of Parkinson's disease and applications in clinical trials. Mov Disord (2016) 0.76
Predicting functional decline and survival in amyotrophic lateral sclerosis. PLoS One (2017) 0.75
Industry-academia collaborations for biomarkers. Nat Rev Drug Discov (2015) 0.75
Predicting disease progression in amyotrophic lateral sclerosis. Ann Clin Transl Neurol (2016) 0.75
MISSING DATA IMPUTATION IN THE ELECTRONIC HEALTH RECORD USING DEEPLY LEARNED AUTOENCODERS. Pac Symp Biocomput (2016) 0.75
Comprehensive rehabilitative care across the spectrum of amyotrophic lateral sclerosis. NeuroRehabilitation (2015) 0.75
A Longitudinal Support Vector Regression for Prediction of ALS Score. IEEE Int Conf Bioinform Biomed Workshops (2015) 0.75
The Prostate Cancer DREAM Challenge: A Community-Wide Effort to Use Open Clinical Trial Data for the Quantitative Prediction of Outcomes in Metastatic Prostate Cancer. Oncologist (2015) 0.75
New developments and future opportunities in biomarkers for amyotrophic lateral sclerosis. Transl Neurodegener (2015) 0.75
Modeling cytokine regulatory network dynamics driving neuroinflammation in central nervous system disorders. Drug Discov Today Dis Models (2017) 0.75
Crowdsourcing to promote HIV testing among MSM in China: study protocol for a stepped wedge randomized controlled trial. Trials (2017) 0.75
Patients with ALS show highly correlated progression rates in left and right limb muscles. Neurology (2017) 0.75
The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci (1999) 9.95
Wisdom of crowds for robust gene network inference. Nat Methods (2012) 6.91
Amyotrophic lateral sclerosis. Lancet (2011) 5.86
Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Brain (1999) 4.41
A predictive model for progression of chronic kidney disease to kidney failure. JAMA (2011) 4.22
Prognosis in amyotrophic lateral sclerosis: a population-based study. Neurology (2003) 3.14
Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis. Muscle Nerve (2011) 2.85
Serum uric acid levels and the risk of Parkinson disease. Ann Neurol (2005) 2.47
Urate as a predictor of the rate of clinical decline in Parkinson disease. Arch Neurol (2009) 2.46
Phase II screening trial of lithium carbonate in amyotrophic lateral sclerosis: examining a more efficient trial design. Neurology (2011) 2.28
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND). Cochrane Database Syst Rev (2007) 2.20
Prize-based contests can provide solutions to computational biology problems. Nat Biotechnol (2013) 1.95
Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trials. J Neurol Sci (1997) 1.77
Amyotrophic lateral sclerosis in an urban setting: a population based study of inner city London. J Neurol (2006) 1.61
Onset and spreading patterns of lower motor neuron involvements predict survival in sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry (2011) 1.53
Disease progression in amyotrophic lateral sclerosis: predictors of survival. Muscle Nerve (2002) 1.47
The incidence of amyotrophic lateral sclerosis in Friuli Venezia Giulia, Italy, from 2002 to 2009: a retrospective population-based study. Neuroepidemiology (2013) 1.43
Serum uric acid and cognitive function and dementia. Brain (2008) 1.30
The PRO-ACT database: design, initial analyses, and predictive features. Neurology (2014) 1.26
ALSFRS-R score and its ratio: a useful predictor for ALS-progression. J Neurol Sci (2008) 1.22
Seeking the wisdom of crowds through challenge-based competitions in biomedical research. Clin Pharmacol Ther (2013) 1.18
Functional outcome measures as clinical trial endpoints in ALS. Neurology (2004) 1.15
ALS clinical trials: do enrolled patients accurately represent the ALS population? Neurology (2011) 1.14
Impairment of cardiac autonomic control in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler (2010) 1.08
Analysis of factors that modify susceptibility and rate of progression in amyotrophic lateral sclerosis (ALS). Amyotroph Lateral Scler (2006) 1.08
Analysis of survival and prognostic factors in amyotrophic lateral sclerosis: a population based study. J Neurol Neurosurg Psychiatry (2007) 1.05
Predictability of disease progression in amyotrophic lateral sclerosis. Muscle Nerve (2006) 1.03
Pattern of spread and prognosis in lower limb-onset ALS. Amyotroph Lateral Scler (2010) 1.02
Autonomic impairment in amyotrophic lateral sclerosis. Curr Opin Neurol (2005) 1.00
Combining patient-level and summary-level data for Alzheimer's disease modeling and simulation: a β regression meta-analysis. J Pharmacokinet Pharmacodyn (2012) 1.00
Uric acid levels predict survival in men with amyotrophic lateral sclerosis. J Neurol (2012) 0.97
The relationship between uric acid levels and Huntington's disease progression. Mov Disord (2010) 0.96
Alzheimer's disease: diagnostics, prognostics and the road to prevention. EPMA J (2010) 0.96
Relationships between disease progression and serum levels of lipid, urate, creatinine and ferritin in Japanese patients with amyotrophic lateral sclerosis: a cross-sectional study. Intern Med (2012) 0.96
The Coalition Against Major Diseases: developing tools for an integrated drug development process for Alzheimer's and Parkinson's diseases. Clin Pharmacol Ther (2009) 0.94
Body mass index (BMI) as predictor of ALSFRS-R score decline in ALS patients. Amyotroph Lateral Scler Frontotemporal Degener (2013) 0.93
RandomForest4Life: a Random Forest for predicting ALS disease progression. Amyotroph Lateral Scler Frontotemporal Degener (2014) 0.92
Amyotrophic lateral sclerosis disease progression model. Amyotroph Lateral Scler Frontotemporal Degener (2013) 0.92
Revisiting the multiple sclerosis functional composite: proceedings from the National Multiple Sclerosis Society (NMSS) Task Force on Clinical Disability Measures. Mult Scler (2012) 0.90
Serum creatine kinase levels in spinobulbar muscular atrophy and amyotrophic lateral sclerosis. Muscle Nerve (2009) 0.85
An abnormal relationship between blood pressure and pulse rate in amyotrophic lateral sclerosis. Acta Neurol Scand (1997) 0.82
What does body mass index measure in amyotrophic lateral sclerosis and why should we care? Muscle Nerve (2012) 0.81
Factors associated with survival in the National Registry of Veterans with ALS. Amyotroph Lateral Scler (2009) 0.79
Respiratory systems abnormalities and clinical milestones for patients with amyotrophic lateral sclerosis with emphasis upon survival. Amyotroph Lateral Scler (2007) 0.78
Medications and laboratory parameters as prognostic factors in amyotrophic lateral sclerosis. Amyotroph Lateral Scler (2008) 0.78
Blood pressure measurements in a transgenic SOD1-G93A mouse model of amyotrophic lateral sclerosis. Amyotroph Lateral Scler (2012) 0.76
An exploratory study of serum creatinine levels in patients with amyotrophic lateral sclerosis. Neurol Sci (2014) 0.76