Published in Biochem Cell Biol on September 12, 2014
Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3. J Physiol (2002) 1.22
Molecular determinants of Au(CN)(2)(-) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(-) channel pore. J Physiol (2002) 1.22
Positive charges at the intracellular mouth of the pore regulate anion conduction in the CFTR chloride channel. J Gen Physiol (2006) 1.18
Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore. J Gen Physiol (2010) 1.07
Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Biol Chem (2004) 1.06
Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel. J Biol Chem (2010) 1.03
Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore. J Gen Physiol (2003) 1.01
State-dependent access of anions to the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Biol Chem (2007) 1.00
Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore. Pflugers Arch (2008) 0.99
Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. J Biol Chem (2004) 0.99
Molecular determinants and role of an anion binding site in the external mouth of the CFTR chloride channel pore. J Physiol (2003) 0.98
Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Gen Physiol (2011) 0.98
Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant. Pflugers Arch (2011) 0.96
Mechanism of direct bicarbonate transport by the CFTR anion channel. J Cyst Fibros (2008) 0.94
Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: implications for cystic fibrosis lung disease. J Physiol (2002) 0.93
Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore. Mol Pharmacol (2007) 0.92
Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel. J Membr Biol (2011) 0.92
Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7. Oncol Rep (2008) 0.92
Coupled movement of permeant and blocking ions in the CFTR chloride channel pore. J Physiol (2003) 0.90
Contribution of KCNQ1 to the regulatory volume decrease in the human mammary epithelial cell line MCF-7. Am J Physiol Cell Physiol (2007) 0.90
Alternating access to the transmembrane domain of the ATP-binding cassette protein cystic fibrosis transmembrane conductance regulator (ABCC7). J Biol Chem (2012) 0.89
Point mutations in the pore region directly or indirectly affect glibenclamide block of the CFTR chloride channel. Pflugers Arch (2001) 0.88
Tyrosine kinase and phosphatase regulation of slow delayed-rectifier K+ current in guinea-pig ventricular myocytes. J Physiol (2006) 0.88
Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating. Biochim Biophys Acta (2012) 0.87
Regulation of CFTR chloride channel macroscopic conductance by extracellular bicarbonate. Am J Physiol Cell Physiol (2010) 0.87
Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines. J Membr Biol (2009) 0.87
Relative movements of transmembrane regions at the outer mouth of the cystic fibrosis transmembrane conductance regulator channel pore during channel gating. J Biol Chem (2012) 0.86
Mechanism of lonidamine inhibition of the CFTR chloride channel. Br J Pharmacol (2002) 0.86
On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore. Biophys J (2006) 0.85
Direct and indirect effects of mutations at the outer mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Membr Biol (2007) 0.84
Relative contribution of different transmembrane segments to the CFTR chloride channel pore. Pflugers Arch (2013) 0.82
The patch-clamp and planar lipid bilayer techniques: powerful and versatile tools to investigate the CFTR Cl- channel. J Cyst Fibros (2004) 0.82
Interactions between impermeant blocking ions in the cystic fibrosis transmembrane conductance regulator chloride channel pore: evidence for anion-induced conformational changes. J Membr Biol (2006) 0.81
Role of the juxtamembrane region of cytoplasmic loop 3 in the gating and conductance of the cystic fibrosis transmembrane conductance regulator chloride channel. Biochemistry (2012) 0.80
The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor. Pflugers Arch (2014) 0.79
Exposure to sodium butyrate leads to functional downregulation of calcium-activated potassium channels in human airway epithelial cells. Pflugers Arch (2006) 0.79
Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes. Pflugers Arch (2007) 0.79
Evidence that extracellular anions interact with a site outside the CFTR chloride channel pore to modify channel properties. Can J Physiol Pharmacol (2009) 0.79
Tuning of CFTR chloride channel function by location of positive charges within the pore. Biophys J (2012) 0.79
Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs. Biochim Biophys Acta (2006) 0.79
Molecular mechanism of arachidonic acid inhibition of the CFTR chloride channel. Eur J Pharmacol (2007) 0.78
Maximization of the rate of chloride conduction in the CFTR channel pore by ion-ion interactions. Arch Biochem Biophys (2004) 0.78
Selective block of swelling-activated Cl- channels over cAMP-dependent Cl- channels in ventricular myocytes. Eur J Pharmacol (2004) 0.78
Expression of the chloride channel CLC-K in human airway epithelial cells. Can J Physiol Pharmacol (2005) 0.78
Interaction between 2 extracellular loops influences the activity of the cystic fibrosis transmembrane conductance regulator chloride channel. Biochem Cell Biol (2014) 0.77
Insensitivity of cardiac delayed-rectifier I(Kr) to tyrosine phosphorylation inhibitors and stimulators. Br J Pharmacol (2006) 0.77
Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function. Br J Pharmacol (2012) 0.77
Metal bridges to probe membrane ion channel structure and function. Biomol Concepts (2015) 0.77
Regulation of wild-type and mutant KCNQ1/KCNE1 channels by tyrosine kinase. Pflugers Arch (2009) 0.76
Location of a permeant anion binding site in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Physiol Sci (2015) 0.75