PubRank

Paul Linsdell

Author PubWeight™ 44.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular determinants of Au(CN)(2)(-) binding and permeability within the cystic fibrosis transmembrane conductance regulator Cl(-) channel pore. J Physiol 2002 1.22
2 Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3. J Physiol 2002 1.22
3 Positive charges at the intracellular mouth of the pore regulate anion conduction in the CFTR chloride channel. J Gen Physiol 2006 1.18
4 Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore. J Gen Physiol 2010 1.07
5 Direct comparison of the functional roles played by different transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Biol Chem 2004 1.06
6 Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel. J Biol Chem 2010 1.03
7 Mutation-induced blocker permeability and multiion block of the CFTR chloride channel pore. J Gen Physiol 2003 1.01
8 State-dependent access of anions to the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Biol Chem 2007 1.00
9 Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore. Pflugers Arch 2008 0.99
10 Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. J Biol Chem 2004 0.99
11 Molecular determinants and role of an anion binding site in the external mouth of the CFTR chloride channel pore. J Physiol 2003 0.98
12 Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Gen Physiol 2011 0.98
13 Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant. Pflugers Arch 2011 0.96
14 Mechanism of direct bicarbonate transport by the CFTR anion channel. J Cyst Fibros 2008 0.94
15 Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: implications for cystic fibrosis lung disease. J Physiol 2002 0.93
16 Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7. Oncol Rep 2008 0.92
17 Identification of a second blocker binding site at the cytoplasmic mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore. Mol Pharmacol 2007 0.92
18 Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel. J Membr Biol 2011 0.92
19 Contribution of KCNQ1 to the regulatory volume decrease in the human mammary epithelial cell line MCF-7. Am J Physiol Cell Physiol 2007 0.90
20 Coupled movement of permeant and blocking ions in the CFTR chloride channel pore. J Physiol 2003 0.90
21 Alternating access to the transmembrane domain of the ATP-binding cassette protein cystic fibrosis transmembrane conductance regulator (ABCC7). J Biol Chem 2012 0.89
22 Tyrosine kinase and phosphatase regulation of slow delayed-rectifier K+ current in guinea-pig ventricular myocytes. J Physiol 2006 0.88
23 Point mutations in the pore region directly or indirectly affect glibenclamide block of the CFTR chloride channel. Pflugers Arch 2001 0.88
24 Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating. Biochim Biophys Acta 2012 0.87
25 Novel residues lining the CFTR chloride channel pore identified by functional modification of introduced cysteines. J Membr Biol 2009 0.87
26 Regulation of CFTR chloride channel macroscopic conductance by extracellular bicarbonate. Am J Physiol Cell Physiol 2010 0.87
27 Relative movements of transmembrane regions at the outer mouth of the cystic fibrosis transmembrane conductance regulator channel pore during channel gating. J Biol Chem 2012 0.86
28 Mechanism of lonidamine inhibition of the CFTR chloride channel. Br J Pharmacol 2002 0.86
29 On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore. Biophys J 2006 0.85
30 Direct and indirect effects of mutations at the outer mouth of the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Membr Biol 2007 0.84
31 Relative contribution of different transmembrane segments to the CFTR chloride channel pore. Pflugers Arch 2013 0.82
32 The patch-clamp and planar lipid bilayer techniques: powerful and versatile tools to investigate the CFTR Cl- channel. J Cyst Fibros 2004 0.82
33 Interactions between impermeant blocking ions in the cystic fibrosis transmembrane conductance regulator chloride channel pore: evidence for anion-induced conformational changes. J Membr Biol 2006 0.81
34 Role of the juxtamembrane region of cytoplasmic loop 3 in the gating and conductance of the cystic fibrosis transmembrane conductance regulator chloride channel. Biochemistry 2012 0.80
35 The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor. Pflugers Arch 2014 0.79
36 Evidence that extracellular anions interact with a site outside the CFTR chloride channel pore to modify channel properties. Can J Physiol Pharmacol 2009 0.79
37 Tuning of CFTR chloride channel function by location of positive charges within the pore. Biophys J 2012 0.79
38 Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs. Biochim Biophys Acta 2006 0.79
39 Exposure to sodium butyrate leads to functional downregulation of calcium-activated potassium channels in human airway epithelial cells. Pflugers Arch 2006 0.79
40 Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes. Pflugers Arch 2007 0.79
41 Selective block of swelling-activated Cl- channels over cAMP-dependent Cl- channels in ventricular myocytes. Eur J Pharmacol 2004 0.78
42 Expression of the chloride channel CLC-K in human airway epithelial cells. Can J Physiol Pharmacol 2005 0.78
43 Molecular mechanism of arachidonic acid inhibition of the CFTR chloride channel. Eur J Pharmacol 2007 0.78
44 Maximization of the rate of chloride conduction in the CFTR channel pore by ion-ion interactions. Arch Biochem Biophys 2004 0.78
45 Interaction between 2 extracellular loops influences the activity of the cystic fibrosis transmembrane conductance regulator chloride channel. Biochem Cell Biol 2014 0.77
46 Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function. Br J Pharmacol 2012 0.77
47 Insensitivity of cardiac delayed-rectifier I(Kr) to tyrosine phosphorylation inhibitors and stimulators. Br J Pharmacol 2006 0.77
48 Conformational changes opening and closing the CFTR chloride channel: insights from cysteine scanning mutagenesis. Biochem Cell Biol 2014 0.77
49 Metal bridges to probe membrane ion channel structure and function. Biomol Concepts 2015 0.77
50 Regulation of wild-type and mutant KCNQ1/KCNE1 channels by tyrosine kinase. Pflugers Arch 2009 0.76
51 Location of a permeant anion binding site in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J Physiol Sci 2015 0.75