Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition.

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Published in Blood on November 14, 2014

Authors

Subarna Sinha1, Daniel Thomas2, Linda Yu2, Andrew J Gentles3, Namyoung Jung4, M Ryan Corces-Zimmerman2, Steven M Chan2, Andreas Reinisch2, Andrew P Feinberg4, David L Dill1, Ravindra Majeti2

Author Affiliations

1: Department of Computer Science, Stanford University, Stanford, CA;
2: Division of Hematology, Department of Medicine, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA;
3: Department of Radiology, Stanford University, Stanford, CA; and.
4: Center for Epigenetics, Institute for Basic Biomedical Science, Johns Hopkins School of Medicine, Baltimore, MD.

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