Human pDCs preferentially sense enveloped hepatitis A virions.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 4382264)

Published in J Clin Invest on November 21, 2014

Authors

Zongdi Feng, You Li, Kevin L McKnight, Lucinda Hensley, Robert E Lanford, Christopher M Walker, Stanley M Lemon

Articles citing this

The multifaceted biology of plasmacytoid dendritic cells. Nat Rev Immunol (2015) 1.52

Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery. Microbiol Mol Biol Rev (2016) 0.91

Reassessing immune control of hepatitis A virus. Curr Opin Virol (2015) 0.88

Immune responses and immunopathology in acute and chronic viral hepatitis. Nat Rev Immunol (2016) 0.86

Regulation of the Host Antiviral State by Intercellular Communications. Viruses (2015) 0.84

The Dual Role of Exosomes in Hepatitis A and C Virus Transmission and Viral Immune Activation. Viruses (2015) 0.83

Sensing of latent EBV infection through exosomal transfer of 5'pppRNA. Proc Natl Acad Sci U S A (2016) 0.83

Extracellular vesicles during Herpes Simplex Virus type 1 infection: an inquire. Virol J (2016) 0.79

Cell-Cell Sensing of Viral Infection by Plasmacytoid Dendritic Cells. J Virol (2016) 0.77

Exosomes in Viral Disease. Neurotherapeutics (2016) 0.76

Signed, Sealed, Delivered: Microenvironmental Modulation of Extracellular Vesicle-Dependent Immunoregulation in the Lung. Front Cell Dev Biol (2016) 0.75

Hepatitis E virus persists in the presence of a type III interferon response. PLoS Pathog (2017) 0.75

293tExosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection. PLoS Pathog (2017) 0.75

CXCL10 is produced in hepatitis A virus-infected cells in an IRF3-dependent but IFN-independent manner. Sci Rep (2017) 0.75

NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR. Nat Immunol (2017) 0.75

Articles cited by this

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature (2005) 17.47

Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J Virol (2002) 11.99

Interferon signaling and treatment outcome in chronic hepatitis C. Proc Natl Acad Sci U S A (2008) 8.56

Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science (2007) 7.65

BIOLOGIC CHARACTERISTICS OF A CONTINUOUS KIDNEY CELL LINE DERIVED FROM THE AFRICAN GREEN MONKEY. J Immunol (1963) 7.43

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med (2003) 7.26

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A (2005) 6.64

Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat Rev Immunol (2008) 6.17

Genomic analysis of the host response to hepatitis C virus infection. Proc Natl Acad Sci U S A (2002) 5.28

Virus entry by macropinocytosis. Nat Cell Biol (2009) 3.87

A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature (2013) 3.55

Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. J Virol (2004) 3.43

Plasmacytoid dendritic cells: recent progress and open questions. Annu Rev Immunol (2011) 3.32

Complete nucleotide sequence of a cell culture-adapted variant of hepatitis A virus: comparison with wild-type virus with restricted capacity for in vitro replication. Virology (1988) 2.51

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection. Proc Natl Acad Sci U S A (2010) 2.46

Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proc Natl Acad Sci U S A (2007) 2.38

The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry. Cell Host Microbe (2011) 2.25

Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity. Cell Host Microbe (2012) 2.25

The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J Virol (1998) 2.05

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus. J Immunol (2004) 1.85

Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants. J Immunol Methods (2008) 1.74

Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. Hepatology (2008) 1.64

Hepatitis A virus: from discovery to vaccines. Hepatology (2006) 1.63

Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc Natl Acad Sci U S A (2012) 1.56

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo. J Exp Med (2011) 1.39

ALIX and the multivesicular endosome: ALIX in Wonderland. Trends Cell Biol (2013) 1.38

Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA. Proc Natl Acad Sci U S A (2011) 1.36

Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry. J Virol (2013) 1.29

Cutting Edge: Antibody-mediated TLR7-dependent recognition of viral RNA. J Immunol (2007) 1.28

Heat shock protein-containing exosomes in mid-trimester amniotic fluids. J Reprod Immunol (2008) 1.19

Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD. PLoS Pathog (2011) 1.18

Hepatitis A virus and the origins of picornaviruses. Nature (2014) 1.15

Type 1 interferons and antiviral CD8 T-cell responses. PLoS Pathog (2012) 1.15

Viral induction of low frequency interferon-alpha producing cells. Virology (1994) 1.14

RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors. J Virol (2013) 1.12

Plasmacytoid dendritic cell activation by foot-and-mouth disease virus requires immune complexes. Eur J Immunol (2006) 1.10

Tim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells. Eur J Immunol (2011) 1.08

Dominance of the CD4(+) T helper cell response during acute resolving hepatitis A virus infection. J Exp Med (2012) 1.04

Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice. PLoS Pathog (2014) 1.03

Innate IFNs and plasmacytoid dendritic cells constrain Th2 cytokine responses to rhinovirus: a regulatory mechanism with relevance to asthma. J Immunol (2012) 1.01

Immunology. An interferon paradox. Science (2013) 0.99

Peptide aldehyde inhibitors of hepatitis A virus 3C proteinase. Biochemistry (1995) 0.95

Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV. Virology (1999) 0.94

Plasmacytoid dendritic cells promote rotavirus-induced human and murine B cell responses. J Clin Invest (2013) 0.94

Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection. Hepatology (2012) 0.91

Decoding the complexity of type I interferon to treat persistent viral infections. Trends Microbiol (2013) 0.90

Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens. J Virol (2014) 0.79

Articles by these authors

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (2005) 16.84

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol (2005) 9.11

Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science (2003) 7.91

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A (2005) 6.64

Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells. J Virol (2002) 5.81

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proc Natl Acad Sci U S A (2005) 5.64

Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature (2005) 5.50

HCV persistence and immune evasion in the absence of memory T cell help. Science (2003) 5.23

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. Proc Natl Acad Sci U S A (2006) 4.84

Eteplirsen for the treatment of Duchenne muscular dystrophy. Ann Neurol (2013) 4.57

Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells. Proc Natl Acad Sci U S A (2006) 4.54

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology (2002) 4.34

Dystrophin immunity in Duchenne's muscular dystrophy. N Engl J Med (2010) 4.28

Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection. J Exp Med (2003) 4.20

Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins. Ann Neurol (2009) 3.69

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro. Proc Natl Acad Sci U S A (2006) 3.69

A pathogenic picornavirus acquires an envelope by hijacking cellular membranes. Nature (2013) 3.55

Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chimeric hepatitis C virus. J Virol (2006) 3.45

Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. J Virol (2004) 3.43

Visualizing hepatitis C virus infections in human liver by two-photon microscopy. Gastroenterology (2009) 3.07

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology (2002) 3.02

Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells. J Virol (2004) 2.76

Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes. J Biol Chem (2005) 2.70

NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly. J Virol (2008) 2.62

Public health and biosecurity. Adaptations of avian flu virus are a cause for concern. Science (2012) 2.52

Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122. J Virol (2010) 2.51

3' nontranslated RNA signals required for replication of hepatitis C virus RNA. J Virol (2003) 2.41

Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proc Natl Acad Sci U S A (2012) 2.39

Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proc Natl Acad Sci U S A (2007) 2.38

Global surveillance of emerging Influenza virus genotypes by mass spectrometry. PLoS One (2007) 2.29

Fast thermal calibration of low-grade inertial sensors and inertial measurement units. Sensors (Basel) (2013) 2.29

Follistatin gene delivery enhances muscle growth and strength in nonhuman primates. Sci Transl Med (2009) 2.21

Multiple mRNA decapping enzymes in mammalian cells. Mol Cell (2010) 2.12

Detection of diarrheagenic Escherichia coli by use of melting-curve analysis and real-time multiplex PCR. J Clin Microbiol (2008) 2.11

Cell-mediated immunity and the outcome of hepatitis C virus infection. Annu Rev Microbiol (2004) 2.03

Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D. Ann Neurol (2010) 2.02

Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus. Gastroenterology (2010) 1.96

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS. J Virol (2006) 1.86

Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. J Virol (2009) 1.85

Gentamicin-induced readthrough of stop codons in Duchenne muscular dystrophy. Ann Neurol (2010) 1.81

Limited T cell receptor diversity of HCV-specific T cell responses is associated with CTL escape. J Exp Med (2004) 1.79

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate. PLoS Pathog (2012) 1.79

Virus-host cell interactions during hepatitis C virus RNA replication: impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis. J Virol (2004) 1.74

Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication. Proc Natl Acad Sci U S A (2012) 1.73

Unique Kir2.x properties determine regional and species differences in the cardiac inward rectifier K+ current. Circ Res (2004) 1.70

Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man. J Exp Med (2005) 1.69

Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins. J Virol (2010) 1.66

Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses. Nat Med (2013) 1.65

Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. Hepatology (2008) 1.64

Definition of a conserved immunodominant domain on hepatitis C virus E2 glycoprotein by neutralizing human monoclonal antibodies. J Virol (2008) 1.63

Hepatitis A virus: from discovery to vaccines. Hepatology (2006) 1.63

Subgenomic hepatitis C virus replicons inducing expression of a secreted enzymatic reporter protein. Virology (2002) 1.62

Nonstructural protein precursor NS4A/B from hepatitis C virus alters function and ultrastructure of host secretory apparatus. J Virol (2003) 1.62

Activity of a potent hepatitis C virus polymerase inhibitor in the chimpanzee model. Antimicrob Agents Chemother (2007) 1.58

Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studies. J Virol (2010) 1.55

Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design. Protein Sci (2006) 1.55

Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations. J Biol Chem (2005) 1.54

Policy: Adaptations of avian flu virus are a cause for concern. Nature (2012) 1.54

Trans-complementation of an NS2 defect in a late step in hepatitis C virus (HCV) particle assembly and maturation. PLoS Pathog (2009) 1.52

Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost. Ophthalmic Res (2009) 1.51

Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step. J Virol (2011) 1.49

Hepatitis C virus core protein inhibits deoxycholic acid-mediated apoptosis despite generating mitochondrial reactive oxygen species. J Gastroenterol (2006) 1.47

A novel transdermal plasmid-dimethylsulfoxide delivery technique for treatment of psoriasis. Dermatology (2010) 1.45

DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation. J Virol (2010) 1.45

Screening for hepatitis C virus antiviral activity with a cell-based secreted alkaline phosphatase reporter replicon system. Antiviral Res (2005) 1.45

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy. Circulation (2012) 1.44

DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet (2013) 1.44

New Fungus-Insect Symbiosis: Culturing, Molecular, and Histological Methods Determine Saprophytic Polyporales Mutualists of Ambrosiodmus Ambrosia Beetles. PLoS One (2015) 1.43

Structure-function analysis of the 3' stem-loop of hepatitis C virus genomic RNA and its role in viral RNA replication. RNA (2003) 1.41

Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14. J Virol (2002) 1.40

Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein. J Virol (2005) 1.38

Acute hepatitis A virus infection is associated with a limited type I interferon response and persistence of intrahepatic viral RNA. Proc Natl Acad Sci U S A (2011) 1.36

Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees. PLoS Pathog (2012) 1.35

Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery. Mol Ther (2009) 1.35

A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase. J Biol Chem (2008) 1.35

In search of biosecurity. Science (2006) 1.33

Intracellular proton conductance of the hepatitis C virus p7 protein and its contribution to infectious virus production. PLoS Pathog (2010) 1.31

Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein. J Gen Virol (2009) 1.30

Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein. PLoS Pathog (2007) 1.29

Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatitis C virus polyprotein. Gastroenterology (2006) 1.29

Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase. Proc Natl Acad Sci U S A (2005) 1.29

Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus. Virology (2007) 1.28

Mapping of the hepatitis B virus pre-S1 domain involved in receptor recognition. J Virol (2005) 1.25

miR-122 does not modulate the elongation phase of hepatitis C virus RNA synthesis in isolated replicase complexes. Antiviral Res (2010) 1.25

In vitro selection of a neutralization-resistant hepatitis C virus escape mutant. Proc Natl Acad Sci U S A (2008) 1.25

Base pairing between hepatitis C virus RNA and microRNA 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus. J Virol (2012) 1.25

Stable cytotoxic T cell escape mutation in hepatitis C virus is linked to maintenance of viral fitness. PLoS Pathog (2008) 1.24

Silencing of T lymphocytes by antigen-driven programmed death in recombinant adeno-associated virus vector-mediated gene therapy. Blood (2008) 1.24

Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis. J Virol (2011) 1.24