Virus entry by macropinocytosis.

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Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog (2010) 2.60

Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes. PLoS Pathog (2010) 2.60

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Entry of human papillomavirus type 16 by actin-dependent, clathrin- and lipid raft-independent endocytosis. PLoS Pathog (2012) 1.76

A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism. Cancer Res (2010) 1.72

Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway. PLoS Pathog (2011) 1.66

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Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes. J Virol (2010) 1.52

Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry. Proc Natl Acad Sci U S A (2010) 1.45

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A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics. PLoS Pathog (2010) 1.39

Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. ACS Nano (2011) 1.38

Kaposi's sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection. Proc Natl Acad Sci U S A (2012) 1.38

The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus. J Virol (2010) 1.36

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Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein. PLoS Pathog (2013) 1.35

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Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis. J Infect Dis (2011) 1.33

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Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. J Biol Chem (2013) 1.24

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway. Virology (2011) 1.22

Prion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic target. J Biol Chem (2014) 1.20

Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway. Cell Host Microbe (2011) 1.19

Macropinocytotic uptake and infection of human epithelial cells with species B2 adenovirus type 35. J Virol (2010) 1.17

Appraising the apoptotic mimicry model and the role of phospholipids for poxvirus entry. Proc Natl Acad Sci U S A (2009) 1.15

Filovirus entry into cells - new insights. Curr Opin Virol (2012) 1.14

Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner. PLoS One (2012) 1.14

Characterization of entry and infection of monocytic THP-1 cells by Kaposi's sarcoma associated herpesvirus (KSHV): role of heparan sulfate, DC-SIGN, integrins and signaling. Virology (2010) 1.13

RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors. J Virol (2013) 1.12

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Integrative functional genomics of hepatitis C virus infection identifies host dependencies in complete viral replication cycle. PLoS Pathog (2014) 1.11

A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells. PLoS One (2010) 1.11

A differential role for macropinocytosis in mediating entry of the two forms of vaccinia virus into dendritic cells. PLoS Pathog (2010) 1.11

PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway. PLoS Pathog (2012) 1.10

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent. PLoS One (2011) 1.10

African swine fever virus uses macropinocytosis to enter host cells. PLoS Pathog (2012) 1.10

Scavenger receptor mediated endocytosis of silver nanoparticles into J774A.1 macrophages is heterogeneous. ACS Nano (2012) 1.09

Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus. PLoS Pathog (2010) 1.09

Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways. J Control Release (2011) 1.08

Insight into nanoparticle cellular uptake and intracellular targeting. J Control Release (2014) 1.08

Dynamin- and clathrin-dependent endocytosis in African swine fever virus entry. J Virol (2009) 1.06

Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles. J Biol Chem (2011) 1.05

Vaccinia extracellular virions enter cells by macropinocytosis and acid-activated membrane rupture. EMBO J (2011) 1.04

Single-virus tracking reveals a spatial receptor-dependent search mechanism. Biophys J (2011) 1.04

Endocytosis of gene delivery vectors: from clathrin-dependent to lipid raft-mediated endocytosis. Mol Ther (2013) 1.03

Viral determinants of HIV-1 macrophage tropism. Viruses (2011) 1.03

Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin. J Virol (2010) 1.02

Rift Valley fever virus strain MP-12 enters mammalian host cells via caveola-mediated endocytosis. J Virol (2012) 1.02

Filamentous influenza virus enters cells via macropinocytosis. J Virol (2012) 1.02

Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells. J Virol (2011) 1.02

Review: placenta-specific microRNAs in exosomes - good things come in nano-packages. Placenta (2013) 1.02

Receptor-independent fluid-phase pinocytosis mechanisms for induction of foam cell formation with native low-density lipoprotein particles. Curr Opin Lipidol (2011) 1.02

Interaction of bacteriophage l with its E. coli receptor, LamB. Viruses (2012) 1.01

Internalization of isolated functional mitochondria: involvement of macropinocytosis. J Cell Mol Med (2014) 1.01

Epstein-Barr virus transcytosis through polarized oral epithelial cells. J Virol (2013) 1.01

The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses (2011) 0.99

Determining the macropinocytic index of cells through a quantitative image-based assay. Nat Protoc (2014) 0.99

Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation. Sci Rep (2013) 0.99

Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer. World J Gastroenterol (2012) 0.97

αVβ3-integrin relocalizes nectin1 and routes herpes simplex virus to lipid rafts. J Virol (2011) 0.96

Engineered nanomaterial uptake and tissue distribution: from cell to organism. Int J Nanomedicine (2013) 0.95

pHLIP®-mediated delivery of PEGylated liposomes to cancer cells. J Control Release (2013) 0.95

Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach. PLoS Genet (2010) 0.94

The ORF3 protein of hepatitis E virus delays degradation of activated growth factor receptors by interacting with CIN85 and blocking formation of the Cbl-CIN85 complex. J Virol (2010) 0.94

Human Ebola virus infection in West Africa: a review of available therapeutic agents that target different steps of the life cycle of Ebola virus. Infect Dis Poverty (2014) 0.94

Elucidating the mechanisms of nickel compound uptake: a review of particulate and nano-nickel endocytosis and toxicity. Toxicol Appl Pharmacol (2011) 0.94

Myxoma and vaccinia viruses exploit different mechanisms to enter and infect human cancer cells. Virology (2010) 0.93

Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors. J Virol (2011) 0.93

Functional roles for myosin 1c in cellular signaling pathways. Cell Signal (2012) 0.92

Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery. Microbiol Mol Biol Rev (2016) 0.91

Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus. PLoS One (2010) 0.91

Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells. Front Physiol (2015) 0.91

Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway. J Virol (2010) 0.90

Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics. Biochemistry (2013) 0.90

Live cell imaging of viral entry. Curr Opin Virol (2013) 0.90

Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation. Front Physiol (2014) 0.90

Enhanced cellular uptake of maleimide-modified liposomes via thiol-mediated transport. Int J Nanomedicine (2014) 0.90

Human pDCs preferentially sense enveloped hepatitis A virions. J Clin Invest (2014) 0.89

Orthobunyavirus entry into neurons and other mammalian cells occurs via clathrin-mediated endocytosis and requires trafficking into early endosomes. J Virol (2012) 0.89

Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner. J Virol (2014) 0.89

Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Proc Natl Acad Sci U S A (2014) 0.89

Macropinocytosis is the entry mechanism of amphotropic murine leukemia virus. J Virol (2014) 0.88

A growth factor signaling cascade confined to circular ruffles in macrophages. Biol Open (2012) 0.88

A cholesterol recognition amino acid consensus domain in GP64 fusion protein facilitates anchoring of baculovirus to mammalian cells. J Virol (2013) 0.88

Internalization of p53(14-29) peptide amphiphiles and subsequent endosomal disruption results in SJSA-1 cell death. Mol Pharm (2010) 0.88

Inhibition of MLC phosphorylation restricts replication of influenza virus--a mechanism of action for anti-influenza agents. PLoS One (2011) 0.88

Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells. Nucleic Acid Ther (2012) 0.88

Catabolic pathways regulated by mTORC1 are pivotal for survival and growth of cancer cells expressing mutant Ras. Oncotarget (2015) 0.88

Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation. Mol Oncol (2015) 0.88

Prions and Protein Assemblies that Convey Biological Information in Health and Disease. Neuron (2016) 0.87

GE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation. Int J Nanomedicine (2014) 0.87

Small rho GTPases and cholesterol biosynthetic pathway intermediates in African swine fever virus infection. J Virol (2011) 0.87

Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation. PLoS One (2013) 0.87

Simian hemorrhagic fever virus cell entry is dependent on CD163 and uses a clathrin-mediated endocytosis-like pathway. J Virol (2014) 0.86

Distinct requirements for HIV-cell fusion and HIV-mediated cell-cell fusion. J Biol Chem (2015) 0.86

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