Leeanne Zalameda

Author PubWeight™ 8.12^‹?›

Top papers

Rank	Title	Journal	Year	PubWeight™‹?›
1	Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors.	Biochim Biophys Acta	2011	0.96
2	Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease.	J Med Chem	2014	0.93
3	Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening.	Assay Drug Dev Technol	2007	0.87
4	Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511.	J Med Chem	2012	0.83
5	Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives.	J Med Chem	2011	0.80
6	Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors.	J Med Chem	2015	0.77
7	Assessment of the integrity of compounds stored in assay-ready plates using a kinase sentinel assay.	Comb Chem High Throughput Screen	2013	0.77
8	N-substituted azaindoles as potent inhibitors of Cdc7 kinase.	Bioorg Med Chem Lett	2013	0.76
9	Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases.	J Med Chem	2012	0.76
10	The optimization of aminooxadiazoles as orally active inhibitors of Cdc7.	Bioorg Med Chem Lett	2013	0.76
11	Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer's disease.	Bioorg Med Chem Lett	2013	0.75