Published in Exp Toxicol Pathol on December 10, 2014
Heterologous Matrix Metalloproteinase Gene Promoter Activity Allows In Vivo Real-time Imaging of Bleomycin-Induced Lung Fibrosis in Transiently Transgenized Mice. Front Immunol (2017) 0.77
Collagenolytic matrix metalloproteinases in chronic obstructive lung disease and cancer. Cancers (Basel) (2015) 0.76
Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med (2006) 49.95
New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer (2002) 24.71
Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer (2006) 5.58
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell (2005) 3.92
The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am J Respir Crit Care Med (2004) 2.94
Collagenase expression in the lungs of transgenic mice causes pulmonary emphysema. Cell (1992) 2.75
Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer. Nat Med (1996) 2.42
Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted. Physiol Rev (2007) 2.14
Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation. J Biol Chem (2000) 2.12
The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. Hum Mol Genet (2002) 1.99
Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema. Am J Respir Crit Care Med (2001) 1.96
MMP-1 drives immunopathology in human tuberculosis and transgenic mice. J Clin Invest (2011) 1.77
Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke. J Biol Chem (2004) 1.75
MMP-1: the elder of the family. Int J Biochem Cell Biol (2005) 1.60
Proteases and emphysema. Curr Opin Pulm Med (2005) 1.55
Correlation between expression of the matrix metalloproteinase-1 gene in ovarian cancers and an insertion/deletion polymorphism in its promoter region. Cancer Res (1999) 1.38
Disruption of the myocardial extracellular matrix leads to cardiac dysfunction. J Clin Invest (2000) 1.33
Interrelationships between the human alveolar macrophage and alpha-1-antitrypsin. J Clin Invest (1973) 1.30
Matrix metalloproteinase inhibitors for cancer therapy:the current situation and future prospects. Expert Opin Ther Targets (2003) 1.27
ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis. J Clin Invest (2001) 1.24
TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease. J Biol Chem (2011) 1.18
Identification of a cigarette smoke-responsive region in the distal MMP-1 promoter. Am J Respir Cell Mol Biol (2008) 1.17
MMP-1 expression has an independent prognostic value in breast cancer. BMC Cancer (2011) 1.04
Emerging role of MAP kinase pathways as therapeutic targets in COPD. Int J Chron Obstruct Pulmon Dis (2006) 1.03
Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling. Toxicol Sci (2011) 0.96
CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke. Am J Physiol Lung Cell Mol Physiol (2014) 0.93
Matrix metalloprotease 1a deficiency suppresses tumor growth and angiogenesis. Oncogene (2013) 0.92
Tobacco smoke-induced lung emphysema in guinea pigs is associated with increased interstitial collagenase. Am J Physiol (1996) 0.90
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. J Biol Chem (2013) 0.89
Overexpression of MMP-1 and VEGF-C is associated with a less favorable prognosis in esophageal squamous cell carcinoma. Onkologie (2012) 0.85
Bone growth retardation in mouse embryos expressing human collagenase 1. Am J Physiol Cell Physiol (2007) 0.83
Cigarette smoke extract induces select matrix metalloproteinases and integrin expression in periodontal ligament fibroblasts. J Periodontol (2011) 0.82
Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study. Respir Res (2012) 0.77
Retracted Transgenic expression of human matrix metalloproteinase-1 attenuates pulmonary arterial hypertension in mice. Clin Sci (Lond) (2012) 0.77