Published in Nat Commun on December 17, 2014
Molecular Machines Regulating the Release Probability of Synaptic Vesicles at the Active Zone. Front Synaptic Neurosci (2016) 0.77
The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming. J Cell Biol (2016) 0.76
Navigation through the Plasma Membrane Molecular Landscape Shapes Random Organelle Movement. Curr Biol (2017) 0.75
CRACM3 regulates the stability of non-excitable exocytotic vesicle fusion pores in a Ca(2+)-independent manner via molecular interaction with syntaxin4. Sci Rep (2016) 0.75
Imaging intracellular fluorescent proteins at nanometer resolution. Science (2006) 38.97
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat Methods (2006) 30.70
Ultra-high resolution imaging by fluorescence photoactivation localization microscopy. Biophys J (2006) 19.98
SNAP receptors implicated in vesicle targeting and fusion. Nature (1993) 18.57
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature (1998) 15.80
Membrane fusion: grappling with SNARE and SM proteins. Science (2009) 8.98
High-density mapping of single-molecule trajectories with photoactivated localization microscopy. Nat Methods (2008) 7.87
Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles. Cell (1996) 5.18
A conformational switch in syntaxin during exocytosis: role of munc18. EMBO J (1999) 5.07
Synaptic vesicle membrane fusion complex: action of clostridial neurotoxins on assembly. EMBO J (1994) 5.02
Single-molecule speckle analysis of actin filament turnover in lamellipodia. Science (2002) 4.27
Selective activation of cognate SNAREpins by Sec1/Munc18 proteins. Cell (2007) 4.26
SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast. Cell (1990) 4.05
Calcium accelerates endocytosis of vSNAREs at hippocampal synapses. Nat Neurosci (2001) 3.68
Direct stochastic optical reconstruction microscopy with standard fluorescent probes. Nat Protoc (2011) 3.07
Munc18-1 binds directly to the neuronal SNARE complex. Proc Natl Acad Sci U S A (2007) 3.03
n-Sec1: a neural-specific syntaxin-binding protein. Proc Natl Acad Sci U S A (1994) 2.95
Munc18-1 promotes large dense-core vesicle docking. Neuron (2001) 2.71
Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron (1998) 2.68
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science (2014) 2.49
Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Science (2008) 2.44
BoxPlotR: a web tool for generation of box plots. Nat Methods (2014) 2.21
Control of fusion pore dynamics during exocytosis by Munc18. Science (2001) 2.11
Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes. Cell (2009) 2.06
Fast vesicle fusion in living cells requires at least three SNARE complexes. Science (2010) 2.06
Three SNARE complexes cooperate to mediate membrane fusion. Proc Natl Acad Sci U S A (2001) 1.91
The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin. J Biol Chem (1995) 1.81
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming. J Cell Biol (2009) 1.80
Ultrasensitive investigations of biological systems by fluorescence correlation spectroscopy. Methods (2003) 1.77
Functionally and spatially distinct modes of munc18-syntaxin 1 interaction. J Biol Chem (2007) 1.66
SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions. Mol Biol Cell (2007) 1.62
Multi-dimensional time-correlated single photon counting (TCSPC) fluorescence lifetime imaging microscopy (FLIM) to detect FRET in cells. J Microsc (2004) 1.55
Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming. J Neurosci (2007) 1.50
Munc18-1 prevents the formation of ectopic SNARE complexes in living cells. J Cell Sci (2007) 1.27
Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1. J Cell Sci (1999) 1.23
Syntaxin 1A is delivered to the apical and basolateral domains of epithelial cells: the role of munc-18 proteins. J Cell Sci (2001) 1.17
Phosphorylated syntaxin 1 is localized to discrete domains along a subset of axons. J Neurosci (2000) 1.15
Munc18-1 mutations that strongly impair SNARE-complex binding support normal synaptic transmission. EMBO J (2012) 1.11
t-SNARE protein conformations patterned by the lipid microenvironment. J Biol Chem (2010) 1.07
Structure and dynamics of a two-helix SNARE complex in live cells. Traffic (2009) 1.02
Fluorescence resonance energy transfer reports properties of syntaxin1a interaction with Munc18-1 in vivo. J Biol Chem (2004) 1.02
A molecular basis underlying differences in the toxicity of botulinum serotypes A and E. EMBO Rep (2004) 1.01
Cytotoxicity of botulinum neurotoxins reveals a direct role of syntaxin 1 and SNAP-25 in neuron survival. Nat Commun (2013) 0.99
S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding. Biochem J (2008) 0.97
Munc18/Syntaxin interaction kinetics control secretory vesicle dynamics. J Biol Chem (2009) 0.94
Secretory vesicles are preferentially targeted to areas of low molecular SNARE density. PLoS One (2012) 0.92
An adaptive non-local means filter for denoising live-cell images and improving particle detection. J Struct Biol (2010) 0.89
Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. J Cell Biol (2014) 0.87
Dance of the SNAREs: assembly and rearrangements detected with FRET at neuronal synapses. J Neurosci (2013) 0.85
Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation. Proc Natl Acad Sci U S A (2013) 0.84
Munc18-1 protein molecules move between membrane molecular depots distinct from vesicle docking sites. J Biol Chem (2012) 0.83
The t-SNARE complex: a close up. Cell Mol Neurobiol (2010) 0.82
Vesicle fusion probability is determined by the specific interactions of munc18. J Biol Chem (2010) 0.81
Membrane protein dynamics and functional implications in mammalian cells. Curr Top Membr (2013) 0.79