The proteasomal Rpn11 metalloprotease suppresses tombusvirus RNA recombination and promotes viral replication via facilitating assembly of the viral replicase complex.

PubWeight™: 0.79‹?›

🔗 View Article (PMC 4325744)

Published in J Virol on December 24, 2014

Authors

K Reddisiva Prasanth1, Daniel Barajas1, Peter D Nagy2

Author Affiliations

1: Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA.
2: Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA pdnagy2@uky.edu.

Articles cited by this

Evolutionary aspects of recombination in RNA viruses. J Gen Virol (1999) 3.74

New insights into the mechanisms of RNA recombination. Virology (1997) 2.41

Systematic exploration of essential yeast gene function with temperature-sensitive mutants. Nat Biotechnol (2011) 2.26

Localization of the tomato bushy stunt virus replication protein p33 reveals a peroxisome-to-endoplasmic reticulum sorting pathway. Plant Cell (2005) 1.98

Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome. J Biol Chem (2003) 1.80

Yeast genome-wide screen reveals dissimilar sets of host genes affecting replication of RNA viruses. Proc Natl Acad Sci U S A (2005) 1.77

Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis. Proc Natl Acad Sci U S A (2008) 1.76

Yeast as a model host to study replication and recombination of defective interfering RNA of Tomato bushy stunt virus. Virology (2003) 1.76

Specific binding of tombusvirus replication protein p33 to an internal replication element in the viral RNA is essential for replication. J Virol (2005) 1.66

The dependence of viral RNA replication on co-opted host factors. Nat Rev Microbiol (2011) 1.66

Proteomics analysis of the tombusvirus replicase: Hsp70 molecular chaperone is associated with the replicase and enhances viral RNA replication. J Virol (2006) 1.64

Role of an internal and two 3'-terminal RNA elements in assembly of tombusvirus replicase. J Virol (2005) 1.63

Purification of the cucumber necrosis virus replicase from yeast cells: role of coexpressed viral RNA in stimulation of replicase activity. J Virol (2004) 1.63

In vitro assembly of the Tomato bushy stunt virus replicase requires the host Heat shock protein 70. Proc Natl Acad Sci U S A (2008) 1.57

A novel 3'-end repair mechanism in an RNA virus. Proc Natl Acad Sci U S A (1997) 1.55

Uncoupled expression of p33 and p92 permits amplification of tomato bushy stunt virus RNAs. J Virol (1998) 1.55

The role of the p33:p33/p92 interaction domain in RNA replication and intracellular localization of p33 and p92 proteins of Cucumber necrosis tombusvirus. Virology (2005) 1.48

A unique role for the host ESCRT proteins in replication of Tomato bushy stunt virus. PLoS Pathog (2009) 1.47

The tomato bushy stunt virus replicase proteins are coordinately expressed and membrane associated. Virology (1995) 1.44

Translation elongation factor 1A is a component of the tombusvirus replicase complex and affects the stability of the p33 replication co-factor. Virology (2009) 1.42

Utilizing the split-ubiquitin membrane yeast two-hybrid system to identify protein-protein interactions of integral membrane proteins. Sci STKE (2005) 1.39

Cdc34p ubiquitin-conjugating enzyme is a component of the tombusvirus replicase complex and ubiquitinates p33 replication protein. J Virol (2008) 1.38

Recombination and polymerase error facilitate restoration of infectivity in brome mosaic virus. J Virol (1993) 1.37

Genome-wide screen identifies host genes affecting viral RNA recombination. Proc Natl Acad Sci U S A (2005) 1.34

The p92 polymerase coding region contains an internal RNA element required at an early step in Tombusvirus genome replication. J Virol (2005) 1.32

The overlapping RNA-binding domains of p33 and p92 replicase proteins are essential for tombusvirus replication. Virology (2003) 1.30

Yeast as a model host to dissect functions of viral and host factors in tombusvirus replication. Virology (2006) 1.29

Screening of the yeast yTHC collection identifies essential host factors affecting tombusvirus RNA recombination. J Virol (2006) 1.23

RNA-RNA recombination in plant virus replication and evolution. Annu Rev Phytopathol (2011) 1.23

Authentic replication and recombination of Tomato bushy stunt virus RNA in a cell-free extract from yeast. J Virol (2008) 1.22

Mutations in the helicase-like domain of protein 1a alter the sites of RNA-RNA recombination in brome mosaic virus. J Virol (1995) 1.20

Participation of the proteasomal lid subunit Rpn11 in mitochondrial morphology and function is mapped to a distinct C-terminal domain. Biochem J (2004) 1.18

Mechanism of RNA recombination in carmo- and tombusviruses: evidence for template switching by the RNA-dependent RNA polymerase in vitro. J Virol (2003) 1.18

Global genomics and proteomics approaches to identify host factors as targets to induce resistance against Tomato bushy stunt virus. Adv Virus Res (2010) 1.17

Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy. J Proteome Res (2010) 1.14

Polymerization of nontemplate bases before transcription initiation at the 3' ends of templates by an RNA-dependent RNA polymerase: an activity involved in 3' end repair of viral RNAs. Proc Natl Acad Sci U S A (2000) 1.13

The AU-rich RNA recombination hot spot sequence of Brome mosaic virus is functional in tombusviruses: implications for the mechanism of RNA recombination. J Virol (2004) 1.13

A mutation in the putative RNA polymerase gene inhibits nonhomologous, but not homologous, genetic recombination in an RNA virus. Proc Natl Acad Sci U S A (1997) 1.12

Recombination in RNA viruses and in virus-resistant transgenic plants. J Gen Virol (1999) 1.11

Suppression of viral RNA recombination by a host exoribonuclease. J Virol (2006) 1.09

Plant RNA virus evolution. Curr Opin Microbiol (2003) 1.08

Host transcription factor Rpb11p affects tombusvirus replication and recombination via regulating the accumulation of viral replication proteins. Virology (2007) 1.07

RNA chaperone activity of the tombusviral p33 replication protein facilitates initiation of RNA synthesis by the viral RdRp in vitro. Virology (2010) 1.06

Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function. Mol Biol Cell (2008) 1.05

Host factors with regulatory roles in tombusvirus replication. Curr Opin Virol (2012) 1.05

The Nedd4-type Rsp5p ubiquitin ligase inhibits tombusvirus replication by regulating degradation of the p92 replication protein and decreasing the activity of the tombusvirus replicase. J Virol (2009) 1.04

Ubiquitination of tombusvirus p33 replication protein plays a role in virus replication and binding to the host Vps23p ESCRT protein. Virology (2009) 1.03

Noncanonical role for the host Vps4 AAA+ ATPase ESCRT protein in the formation of Tomato bushy stunt virus replicase. PLoS Pathog (2014) 1.00

Mutations in the N terminus of the brome mosaic virus polymerase affect genetic RNA-RNA recombination. J Virol (1998) 0.99

Mechanism of DI RNA formation in tombusviruses: dissecting the requirement for primer extension by the tombusvirus RNA dependent RNA polymerase in vitro. Virology (2002) 0.97

Heterologous RNA replication enhancer stimulates in vitro RNA synthesis and template-switching by the carmovirus, but not by the tombusvirus, RNA-dependent RNA polymerase: implication for modular evolution of RNA viruses. Virology (2005) 0.97

Cpr1 cyclophilin and Ess1 parvulin prolyl isomerases interact with the tombusvirus replication protein and inhibit viral replication in yeast model host. Virology (2010) 0.97

A Co-Opted DEAD-Box RNA helicase enhances tombusvirus plus-strand synthesis. PLoS Pathog (2012) 0.97

Expression of the Arabidopsis Xrn4p 5'-3' exoribonuclease facilitates degradation of tombusvirus RNA and promotes rapid emergence of viral variants in plants. Virology (2007) 0.97

Analysis of membrane protein complexes using the split-ubiquitin membrane yeast two-hybrid (MYTH) system. Methods Mol Biol (2009) 0.96

Kinetics and functional studies on interaction between the replicase proteins of Tomato Bushy Stunt Virus: requirement of p33:p92 interaction for replicase assembly. Virology (2005) 0.94

The roles of host factors in tombusvirus RNA recombination. Adv Virus Res (2011) 0.93

A host Ca2+/Mn2+ ion pump is a factor in the emergence of viral RNA recombinants. Cell Host Microbe (2010) 0.93

Silencing of Nicotiana benthamiana Xrn4p exoribonuclease promotes tombusvirus RNA accumulation and recombination. Virology (2009) 0.92

Role of RNase MRP in viral RNA degradation and RNA recombination. J Virol (2010) 0.91

Mutations in the RNA-binding domains of tombusvirus replicase proteins affect RNA recombination in vivo. Virology (2003) 0.90

Genetic recombination in plant-infecting messenger-sense RNA viruses: overview and research perspectives. Front Plant Sci (2013) 0.90

The combined effect of environmental and host factors on the emergence of viral RNA recombinants. PLoS Pathog (2010) 0.88

p33-Independent activation of a truncated p92 RNA-dependent RNA polymerase of Tomato bushy stunt virus in yeast cell-free extract. J Virol (2012) 0.86

Repair of the tRNA-like CCA sequence in a multipartite positive-strand RNA virus. J Virol (2005) 0.85

A nonproteolytic proteasome activity controls organelle fission in yeast. J Cell Sci (2009) 0.83

Repair of lost 5' terminal sequences in tombusviruses: Rapid recovery of promoter- and enhancer-like sequences in recombinant RNAs. Virology (2010) 0.80

Integrity of the Saccharomyces cerevisiae Rpn11 protein is critical for formation of proteasome storage granules (PSG) and survival in stationary phase. PLoS One (2013) 0.78

The JAMM in the proteasome. Nat Struct Mol Biol (2014) 0.78

Analysis of the rpn11-m1 proteasomal mutant reveals connection between cell cycle and mitochondrial biogenesis. FEMS Yeast Res (2010) 0.76