Published in Proc Natl Acad Sci U S A on August 29, 2008
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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol (2009) 2.16
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Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Mol Cell Proteomics (2010) 1.61
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The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries. Mol Cell (2009) 1.45
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Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry. Nat Methods (2015) 1.22
Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. J Proteome Res (2008) 1.20
Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data. J R Soc Interface (2009) 1.19
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A new in vivo cross-linking mass spectrometry platform to define protein-protein interactions in living cells. Mol Cell Proteomics (2014) 1.18
Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy. J Proteome Res (2010) 1.14
Profiling of protein interaction networks of protein complexes using affinity purification and quantitative mass spectrometry. Mol Cell Proteomics (2010) 1.13
Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1. BMC Biol (2011) 1.12
Translating DRiPs: progress in understanding viral and cellular sources of MHC class I peptide ligands. Cell Mol Life Sci (2011) 1.11
Perilous journey: a tour of the ubiquitin-proteasome system. Trends Cell Biol (2014) 1.11
A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. J Biol Chem (2010) 1.10
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Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome. J Biol Chem (2009) 1.08
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Stalled proteasomes are directly relieved by P97 recruitment. J Biol Chem (2011) 1.01
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Mapping the protein interaction network of the human COP9 signalosome complex using a label-free QTAX strategy. Mol Cell Proteomics (2012) 0.98
Network topology reveals key cardiovascular disease genes. PLoS One (2013) 0.96
Effects of ethanol on the proteasome interacting proteins. World J Gastroenterol (2010) 0.95
Osmotic stress inhibits proteasome by p38 MAPK-dependent phosphorylation. J Biol Chem (2010) 0.93
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OLA1 protects cells in heat shock by stabilizing HSP70. Cell Death Dis (2013) 0.92
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Developing new isotope-coded mass spectrometry-cleavable cross-linkers for elucidating protein structures. Anal Chem (2014) 0.90
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Designer reagents for mass spectrometry-based proteomics: clickable cross-linkers for elucidation of protein structures and interactions. Anal Chem (2012) 0.87
A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway. J Biol Chem (2013) 0.86
Subcellular distribution and dynamics of active proteasome complexes unraveled by a workflow combining in vivo complex cross-linking and quantitative proteomics. Mol Cell Proteomics (2012) 0.86
Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe. Mol Biol Cell (2010) 0.84
Mmi1, the yeast homologue of mammalian TCTP, associates with stress granules in heat-shocked cells and modulates proteasome activity. PLoS One (2013) 0.84
Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation. Mol Cell Proteomics (2016) 0.83
Arabidopsis sensitivity to protein synthesis inhibitors depends on 26S proteasome activity. Plant Cell Rep (2010) 0.81
Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions. Fly (Austin) (2012) 0.81
Engineering yeast hexokinase 2 for improved tolerance toward xylose-induced inactivation. PLoS One (2013) 0.81
A pipeline for determining protein-protein interactions and proximities in the cellular milieu. Mol Cell Proteomics (2014) 0.81
Motif-role-fingerprints: the building-blocks of motifs, clustering-coefficients and transitivities in directed networks. PLoS One (2014) 0.80
The proteasomal Rpn11 metalloprotease suppresses tombusvirus RNA recombination and promotes viral replication via facilitating assembly of the viral replicase complex. J Virol (2014) 0.79
Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis. ACS Chem Neurosci (2014) 0.78
Characterizing the dynamics of proteasome complexes by proteomics approaches. Antioxid Redox Signal (2014) 0.77
Functional conservation and divergence of J-domain-containing ZUO1/ZRF orthologs throughout evolution. Planta (2014) 0.77
Quantitative proteomics to decipher ubiquitin signaling. Amino Acids (2012) 0.77
Investigation on the 19S ATPase proteasome subunits (Rpt1-6) conservation and their differential gene expression in Schistosoma mansoni. Parasitol Res (2012) 0.76
Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility. PLoS Genet (2016) 0.76
The Cdc48-Vms1 complex maintains 26S proteasome architecture. Biochem J (2014) 0.75
Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol Cell Proteomics (2017) 0.75
Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells. Oncotarget (2016) 0.75
The Proteasome-Interacting Ecm29 Protein Disassembles the 26S Proteasome in Response to Oxidative Stress. J Biol Chem (2017) 0.75
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Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature (2002) 37.66
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature (2006) 24.29
Proteome survey reveals modularity of the yeast cell machinery. Nature (2006) 20.77
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature (2007) 9.25
Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae. Mol Cell Proteomics (2007) 7.93
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Multiple associated proteins regulate proteasome structure and function. Mol Cell (2002) 4.97
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Structural organization of the 19S proteasome lid: insights from MS of intact complexes. PLoS Biol (2006) 2.56
Mass spectrometric characterization of the affinity-purified human 26S proteasome complex. Biochemistry (2007) 2.43
Mapping the murine cardiac 26S proteasome complexes. Circ Res (2006) 2.17
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Proteasome-associated proteins: regulation of a proteolytic machine. Biol Chem (2005) 2.01
Identifying functional modules in the physical interactome of Saccharomyces cerevisiae. Proteomics (2007) 1.96
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Mammalian proteasome subpopulations with distinct molecular compositions and proteolytic activities. Mol Cell Proteomics (2007) 1.41
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking. Proc Natl Acad Sci U S A (2007) 1.17
Proteasome-dependent degradation of cytosolic chaperonin CCT. Biochem Biophys Res Commun (2000) 0.88
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat Immunol (2010) 5.79
High-throughput mapping of a dynamic signaling network in mammalian cells. Science (2005) 5.21
An elliptic spatial scan statistic. Stat Med (2006) 5.09
A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics (2006) 3.62
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Mass spectrometric characterization of the affinity-purified human 26S proteasome complex. Biochemistry (2007) 2.43
Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase. Neuron (2007) 2.38
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain. Nat Cell Biol (2004) 2.30
Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. J Proteome Res (2008) 2.27
Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity. Am J Physiol Lung Cell Mol Physiol (2007) 2.21
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol (2009) 2.16
Pentatricopeptide repeat proteins stimulate mRNA adenylation/uridylation to activate mitochondrial translation in trypanosomes. Mol Cell (2011) 2.10
Identifying dynamic interactors of protein complexes by quantitative mass spectrometry. Mol Cell Proteomics (2007) 2.02
Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension. Am J Pathol (2008) 1.90
An essential role for stromal interaction molecule 1 in neointima formation following arterial injury. Cardiovasc Res (2008) 1.87
Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Cell (2004) 1.83
The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol (2004) 1.80
Uncovering biological network function via graphlet degree signatures. Cancer Inform (2008) 1.80
Guide RNA-binding complex from mitochondria of trypanosomatids. Mol Cell (2008) 1.75
A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. J Proteome Res (2008) 1.74
The ubiquitin-proteasome system of Saccharomyces cerevisiae. Genetics (2012) 1.73
Topological network alignment uncovers biological function and phylogeny. J R Soc Interface (2010) 1.73
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol (2010) 1.71
A scan statistic for continuous data based on the normal probability model. Int J Health Geogr (2009) 1.68
miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation. Brain Res Bull (2009) 1.66
A technique for retrograde intubation in mice. Lab Anim (NY) (2006) 1.65
Renal D3 dopamine receptor stimulation induces natriuresis by endothelin B receptor interactions. Kidney Int (2008) 1.63
Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Mol Cell Proteomics (2010) 1.61
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J (2002) 1.58
C-reactive protein upregulates receptor for advanced glycation end products expression and alters antioxidant defenses in rat endothelial progenitor cells. J Cardiovasc Pharmacol (2009) 1.57
Histone acetylation and deacetylation: identification of acetylation and methylation sites of HeLa histone H4 by mass spectrometry. Mol Cell Proteomics (2002) 1.52
Oxidative stress-mediated regulation of proteasome complexes. Mol Cell Proteomics (2011) 1.50
Regulation of the 26S proteasome complex during oxidative stress. Sci Signal (2010) 1.48
Geometric de-noising of protein-protein interaction networks. PLoS Comput Biol (2009) 1.46
Cks1-dependent proteasome recruitment and activation of CDC20 transcription in budding yeast. Nature (2003) 1.42
Value of myocardial regional perfusion on long-term function in collateral-dependent myocardium. South Med J (2008) 1.40
Integrative network alignment reveals large regions of global network similarity in yeast and human. Bioinformatics (2011) 1.39
The immunobiology of avian systemic salmonellosis. Vet Immunol Immunopathol (2008) 1.39
Deciphering networks of protein interactions at the nuclear pore complex. Mol Cell Proteomics (2002) 1.37
Activation of D3 dopamine receptor decreases angiotensin II type 1 receptor expression in rat renal proximal tubule cells. Circ Res (2006) 1.36
GraphCrunch: a tool for large network analyses. BMC Bioinformatics (2008) 1.35
Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. J Biol Chem (2009) 1.34
Optimal network alignment with graphlet degree vectors. Cancer Inform (2010) 1.28
Novel avian-origin human influenza A(H7N9) can be transmitted between ferrets via respiratory droplets. J Infect Dis (2013) 1.28
A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome. Nat Cell Biol (2006) 1.26
In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma. Int J Oncol (2007) 1.26
Fitting a geometric graph to a protein-protein interaction network. Bioinformatics (2008) 1.26
GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. Mol Biol Cell (2008) 1.23
HB tag modules for PCR-based gene tagging and tandem affinity purification in Saccharomyces cerevisiae. Yeast (2006) 1.23
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53. Nat Commun (2013) 1.21
Census and geographic differences between respondents and nonrespondents in a case-control study of non-Hodgkin lymphoma. Am J Epidemiol (2007) 1.20
Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. J Proteome Res (2008) 1.20
Comparison of tests for spatial heterogeneity on data with global clustering patterns and outliers. Int J Health Geogr (2009) 1.20
Systems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics data. J R Soc Interface (2009) 1.19
Advanced glycation endproducts alter functions and promote apoptosis in endothelial progenitor cells through receptor for advanced glycation endproducts mediate overpression of cell oxidant stress. Mol Cell Biochem (2009) 1.19
miR-106b aberrantly expressed in a double transgenic mouse model for Alzheimer's disease targets TGF-β type II receptor. Brain Res (2010) 1.18
Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation. Mol Endocrinol (2003) 1.17
Bayesian Variable Selection and Computation for Generalized Linear Models with Conjugate Priors. Bayesian Anal (2008) 1.17
Not all scale-free networks are born equal: the role of the seed graph in PPI network evolution. PLoS Comput Biol (2007) 1.15
Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy. J Proteome Res (2010) 1.14
Profiling of protein interaction networks of protein complexes using affinity purification and quantitative mass spectrometry. Mol Cell Proteomics (2010) 1.13
A phase I study of intravitreal vascular endothelial growth factor trap-eye in patients with neovascular age-related macular degeneration. Ophthalmology (2009) 1.13
An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus. J Pathol (2005) 1.12
Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity. J Natl Cancer Inst (2008) 1.12
beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis. Oncol Rep (2009) 1.11
IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells. Sci Transl Med (2011) 1.11
Mapping the structural topology of the yeast 19S proteasomal regulatory particle using chemical cross-linking and probabilistic modeling. Mol Cell Proteomics (2012) 1.10
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. Cell Rep (2012) 1.09
An essential role for the Id1/PI3K/Akt/NFkB/survivin signalling pathway in promoting the proliferation of endothelial progenitor cells in vitro. Mol Cell Biochem (2011) 1.09
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A (2011) 1.09
The yeast ubiquitin ligase SCFMet30 regulates heavy metal response. Mol Biol Cell (2005) 1.08
Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol (2007) 1.07
AMD3100 mobilizes endothelial progenitor cells in mice, but inhibits its biological functions by blocking an autocrine/paracrine regulatory loop of stromal cell derived factor-1 in vitro. J Cardiovasc Pharmacol (2007) 1.07
Predicting positive p53 cancer rescue regions using Most Informative Positive (MIP) active learning. PLoS Comput Biol (2008) 1.06
Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors. PLoS Comput Biol (2010) 1.06
A novel role for lipid droplets in the organismal antibacterial response. Elife (2012) 1.06
Rethinking peptide supply to MHC class I molecules. Nat Rev Immunol (2007) 1.05
Towards proteome-wide production of monoclonal antibody by phage display. J Mol Biol (2002) 1.05
Global approaches to understanding ubiquitination. Genome Biol (2005) 1.03
Baseline serum uric acid level as a predictor of cardiovascular disease related mortality and all-cause mortality: a meta-analysis of prospective studies. Atherosclerosis (2013) 1.03
Human mesenchymal stem cell transplantation protects against cerebral ischemic injury and upregulates interleukin-10 expression in Macacafascicularis. Brain Res (2010) 1.03
Estimating breast cancer-specific and other-cause mortality in clinical trial and population-based cancer registry cohorts. Cancer (2009) 1.02
Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach. Mol Cell Proteomics (2011) 1.02
Mesenchymal stem cells participating in ex vivo endothelium repair and its effect on vascular smooth muscle cells growth. Int J Cardiol (2005) 1.02
Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease. Cancer Res (2009) 1.01
Ag nanoparticles sensitize IR-induced killing of cancer cells. Cell Res (2009) 1.01
Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3K-dependent pathways. Microvasc Res (2007) 1.01
Selective enrichment and identification of azide-tagged cross-linked peptides using chemical ligation and mass spectrometry. J Am Soc Mass Spectrom (2010) 1.01