HSPA12B inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells.

PubWeight™: 0.76‹?›

🔗 View Article (PMC 4369812)

Published in J Cell Mol Med on December 24, 2014

Authors

Jun Wu1, Xuehan Li, Lei Huang, Surong Jiang, Fei Tu, Xiaojin Zhang, He Ma, Rongrong Li, Chuanfu Li, Yuehua Li, Zhengnian Ding, Li Liu

Author Affiliations

1: Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Articles cited by this

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest (1973) 31.28

Toll-like receptors in the induction of the innate immune response. Nature (2000) 12.23

Origin and physiological roles of inflammation. Nature (2008) 11.68

Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood (1998) 7.70

LPS induction of gene expression in human monocytes. Cell Signal (2001) 7.61

PI3K and negative regulation of TLR signaling. Trends Immunol (2003) 3.70

Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus. JAMA (2004) 3.69

Adhesion molecules and inflammatory injury. FASEB J (1994) 3.53

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. J Leukoc Biol (1994) 2.54

Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway. Proc Natl Acad Sci U S A (2007) 1.95

Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol (2004) 1.65

Vascular-endothelial-cadherin modulates endothelial monolayer permeability. J Cell Sci (1999) 1.57

Molecular basis of endothelial dysfunction in sepsis. Cardiovasc Res (2003) 1.50

Icariin attenuates LPS-induced acute inflammatory responses: involvement of PI3K/Akt and NF-kappaB signaling pathway. Eur J Pharmacol (2010) 1.36

ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation. Am J Physiol Regul Integr Comp Physiol (2002) 1.13

Src-dependent, neutrophil-mediated vascular hyperpermeability and beta-catenin modification. Am J Physiol Cell Physiol (2002) 1.13

The heat-shock response attenuates lipopolysaccharide-mediated apoptosis in cultured sheep pulmonary artery endothelial cells. Am J Respir Cell Mol Biol (1996) 1.04

Two Hsp70 family members expressed in atherosclerotic lesions. Proc Natl Acad Sci U S A (2003) 1.02

ADP stimulates human endothelial cell migration via P2Y1 nucleotide receptor-mediated mitogen-activated protein kinase pathways. Circ Res (2008) 1.01

Attenuation of cardiac dysfunction by HSPA12B in endotoxin-induced sepsis in mice through a PI3K-dependent mechanism. Cardiovasc Res (2010) 0.98

Cholinergic protection via alpha7 nicotinic acetylcholine receptors and PI3K-Akt pathway in LPS-induced neuroinflammation. Neurochem Int (2009) 0.96

A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro. J Cell Sci (2006) 0.96

Isolation of human and mouse neutrophils ex vivo and in vitro. Methods Mol Biol (2012) 0.95

Cardiac-specific expression of heat shock protein 27 attenuated endotoxin-induced cardiac dysfunction and mortality in mice through a PI3K/Akt-dependent mechanism. Shock (2009) 0.95

Mechanisms of leukocyte distribution during sepsis: an experimental study on the interdependence of cell activation, shear stress and endothelial injury. Crit Care (2010) 0.95

HSPA12B is predominantly expressed in endothelial cells and required for angiogenesis. Arterioscler Thromb Vasc Biol (2006) 0.94

Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses. CNS Neurosci Ther (2012) 0.91

Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages. Eur J Pharmacol (2013) 0.90

Amlodipine inhibits TNF-alpha production and attenuates cardiac dysfunction induced by lipopolysaccharide involving PI3K/Akt pathway. Int Immunopharmacol (2009) 0.90

Anti-inflammatory mechanism of exogenous C2 ceramide in lipopolysaccharide-stimulated microglia. Biochim Biophys Acta (2013) 0.88

Bisacurone inhibits adhesion of inflammatory monocytes or cancer cells to endothelial cells through down-regulation of VCAM-1 expression. Int Immunopharmacol (2008) 0.85

Leonurine attenuates lipopolysaccharide-induced inflammatory responses in human endothelial cells: involvement of reactive oxygen species and NF-κB pathways. Eur J Pharmacol (2012) 0.83

Alpha-lipoic acid prevents bupivacaine-induced neuron injury in vitro through a PI3K/Akt-dependent mechanism. Neurotoxicology (2009) 0.83

Heat shock inhibition of lipopolysaccharide-mediated tumor necrosis factor expression is associated with nuclear induction of MKP-1 and inhibition of mitogen-activated protein kinase activation. Crit Care Med (2004) 0.81

Toll-like receptor 4/nuclear factor-κB signaling pathway is involved in ACTG-toxin H-mediated anti-inflammatory effect. Mol Cell Biochem (2012) 0.78

Effects of propyl gallate on adhesion of polymorphonuclear leukocytes to human endothelial cells induced by tumor necrosis factor alpha. Chin J Integr Med (2009) 0.77

Articles by these authors

Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet (2010) 26.48

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res (2004) 21.36

Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71

Global burden of childhood pneumonia and diarrhoea. Lancet (2013) 9.28

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell (2005) 5.51

Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30

ESPRIT: estimating species richness using large collections of 16S rRNA pyrosequences. Nucleic Acids Res (2009) 4.93

Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes. Nat Biotechnol (2011) 4.84

Maternal deaths averted by contraceptive use: an analysis of 172 countries. Lancet (2012) 4.65

Plants and people from the Early Neolithic to Shang periods in North China. Proc Natl Acad Sci U S A (2007) 4.30

Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell (2004) 3.55

Distinct memory traces for two visual features in the Drosophila brain. Nature (2006) 3.48

Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46

Complete genome sequence of citrus huanglongbing bacterium, 'Candidatus Liberibacter asiaticus' obtained through metagenomics. Mol Plant Microbe Interact (2009) 3.33

Evolutionary diagnosis method for variants in personal exomes. Nat Methods (2012) 3.32

Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries. J Glob Health (2013) 3.30

Hormones and menopausal status as predictors of depression in women in transition to menopause. Arch Gen Psychiatry (2004) 3.13

Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990-2010: a systematic review and analysis. Lancet (2013) 3.02

Ending of preventable deaths from pneumonia and diarrhoea: an achievable goal. Lancet (2013) 2.98

Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell (2013) 2.94

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85

Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. J Neurosci (2007) 2.68

Neuronal transcriptome of Aplysia: neuronal compartments and circuitry. Cell (2006) 2.61

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells. Nat Cell Biol (2012) 2.56

Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron (2013) 2.45

Dominance of HIV-1 subtype CRF01_AE in sexually acquired cases leads to a new epidemic in Yunnan province of China. PLoS Med (2006) 2.37

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. Neuron (2004) 2.29

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26

Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload. Cardiovasc Res (2005) 2.24

Nuclear import of the MUC1-C oncoprotein is mediated by nucleoporin Nup62. J Biol Chem (2007) 2.23

Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations. Mol Cancer Ther (2012) 2.21

Ultraflat graphene. Nature (2009) 2.16

A dynamic gene expression atlas covering the entire life cycle of rice. Plant J (2009) 2.15

Identifying major depression using whole-brain functional connectivity: a multivariate pattern analysis. Brain (2012) 2.15

Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality. Crit Care Med (2003) 2.15

Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy. Diabetes Res Clin Pract (2013) 2.12

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse. EMBO J (2008) 2.08

Enhanced detection of low abundance human plasma proteins using a tandem IgY12-SuperMix immunoaffinity separation strategy. Mol Cell Proteomics (2008) 2.08

Collateral vessel opacification with CT in patients with coronary total occlusion and its relationship with downstream myocardial infarction. Radiology (2014) 2.06

Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling. J Immunol (2007) 2.02

The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am J Epidemiol (2009) 2.02

Neural synchronization during face-to-face communication. J Neurosci (2012) 1.99

An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity (2013) 1.98

Hospital episodes and physician visits: the concordance between self-reports and medicare claims. Med Care (2007) 1.96

Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells. Immunogenetics (2005) 1.95

A treatment-resistant default mode subnetwork in major depression. Biol Psychiatry (2012) 1.94

Improved breast cancer prognosis through the combination of clinical and genetic markers. Bioinformatics (2006) 1.93

Activation of telomerase by human cytomegalovirus. J Natl Cancer Inst (2009) 1.92

Epinephrine reduces cerebral perfusion during cardiopulmonary resuscitation. Crit Care Med (2009) 1.91

The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90

GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. PLoS Genet (2012) 1.86

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation. Development (2005) 1.85

A regulatory toolbox of MiniPromoters to drive selective expression in the brain. Proc Natl Acad Sci U S A (2010) 1.85

Autophagy contributes to leaf starch degradation. Plant Cell (2013) 1.85

Activation of Toll-like receptor 4 signaling contributes to hippocampal neuronal death following global cerebral ischemia/reperfusion. J Neuroimmunol (2007) 1.84

MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancer. Clin Cancer Res (2011) 1.80

Etiology and clinical characteristics of membranous nephropathy in Chinese patients. Am J Kidney Dis (2008) 1.80

Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons. J Biol Chem (2012) 1.79

Nucleoside analogue can improve the long-term prognosis of patients with hepatitis B virus infection-associated acute on chronic liver failure. Dig Dis Sci (2010) 1.78

A review of soil heavy metal pollution from mines in China: pollution and health risk assessment. Sci Total Environ (2013) 1.78

Identification of open reading frames unique to a select agent: Ralstonia solanacearum race 3 biovar 2. Mol Plant Microbe Interact (2006) 1.77

Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products. Cell Res (2010) 1.77

Onset of breast and pubic hair development and menses in urban chinese girls. Pediatrics (2009) 1.76

HIV/STD prevalence among men who have sex with men in Chengdu, China and associated risk factors for HIV infection. J Acquir Immune Defic Syndr (2010) 1.76

Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanism. J Immunol (2007) 1.75

A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. Nat Med (2004) 1.75

Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa. Mol Ther (2010) 1.75

Telomerase reconstitution immortalizes human fetal hepatocytes without disrupting their differentiation potential. Gastroenterology (2003) 1.74

Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible Hsp molecular chaperones. J Cell Biochem (2002) 1.73

Involvement of reductive stress in the cardiomyopathy in transgenic mice with cardiac-specific overexpression of heat shock protein 27. Hypertension (2010) 1.73

Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression. J Immunol (2009) 1.72

Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovasc Res (2008) 1.70

Elevated hyaluronan production induces mesenchymal and transformed properties in epithelial cells. J Biol Chem (2003) 1.66

Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J Immunol (2004) 1.65

Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64

Prevalence and rates of recognition of depressive disorders in internal medicine outpatient departments of 23 general hospitals in Shenyang, China. J Affect Disord (2008) 1.63

Evidence of the existence of the low-density liquid phase in supercooled, confined water. Proc Natl Acad Sci U S A (2006) 1.62

Atmospheric oxygen binding and hole doping in deformed graphene on a SiO₂ substrate. Nano Lett (2010) 1.62

Expression and purification of recombinant proteins from Escherichia coli: Comparison of an elastin-like polypeptide fusion with an oligohistidine fusion. Protein Sci (2004) 1.62

Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsis. Crit Care Med (2012) 1.61

Accelerated fat absorption in intestinal alkaline phosphatase knockout mice. Mol Cell Biol (2003) 1.60

MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer. Cancer Res (2009) 1.60

Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumor cells. Cancer Biol Ther (2006) 1.60

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing. Neuron (2008) 1.59

Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms. J Neurosci (2007) 1.58

Hyperactive transposase mutants of the Sleeping Beauty transposon. Mol Ther (2005) 1.58

Screening of patients with tuberculosis for diabetes mellitus in China. Trop Med Int Health (2012) 1.58

Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. EMBO J (2002) 1.58

Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1. Nat Commun (2013) 1.57

The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. J Neurochem (2004) 1.55

Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex. Hepatology (2014) 1.55

Predictors of decreased libido in women during the late reproductive years. Menopause (2004) 1.54

Increases in tissue Pco2 during circulatory shock reflect selective decreases in capillary blood flow. Crit Care Med (2006) 1.54

NF-kappaB activation is required for the development of cardiac hypertrophy in vivo. Am J Physiol Heart Circ Physiol (2004) 1.54

Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc Natl Acad Sci U S A (2004) 1.54