Published in J Biol Chem on December 29, 2014
Cytosolic phospholipase A₂: physiological function and role in disease. J Lipid Res (2015) 1.03
Different Fatty Acids Compete with Arachidonic Acid for Binding to the Allosteric or Catalytic Subunits of Cyclooxygenases to Regulate Prostanoid Synthesis. J Biol Chem (2015) 0.82
Potential Antifungal Targets against a Candida Biofilm Based on an Enzyme in the Arachidonic Acid Cascade-A Review. Front Microbiol (2016) 0.76
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase. Bioorg Med Chem (2016) 0.75
Adaptor Protein p62 Promotes Skin Tumor Growth and Metastasis and is Induced by UVA Radiation. J Biol Chem (2017) 0.75
Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev (2001) 7.60
Bi-directional protein transport between the ER and Golgi. Annu Rev Cell Dev Biol (2004) 6.10
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature (1994) 5.94
A membrane protein required for dislocation of misfolded proteins from the ER. Nature (2004) 5.39
Low-dose aspirin for the prevention of atherothrombosis. N Engl J Med (2005) 4.57
Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science (2011) 3.19
Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate Glc-NAc-1-phosphate transferase. Biochemistry (1979) 2.53
Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention. Chem Rev (2011) 2.48
Control of oxygenation in lipoxygenase and cyclooxygenase catalysis. Chem Biol (2007) 2.29
Recent progress in phospholipase A₂ research: from cells to animals to humans. Prog Lipid Res (2010) 2.17
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology. Physiol Rev (2012) 1.95
The many faces of H89: a review. Cardiovasc Drug Rev (2007) 1.94
Calcium-mediated translocation of cytosolic phospholipase A2 to the nuclear envelope and endoplasmic reticulum. J Biol Chem (1995) 1.90
Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J Biol Chem (1995) 1.82
Protein sorting receptors in the early secretory pathway. Annu Rev Biochem (2010) 1.80
Vascular COX-2 modulates blood pressure and thrombosis in mice. Sci Transl Med (2012) 1.71
COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code. J Cell Biol (2004) 1.70
Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Chem Rev (2011) 1.67
Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents. Cancer Res (2010) 1.66
A molecular specificity code for the three mammalian KDEL receptors. J Cell Biol (2007) 1.64
Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid. Biochemistry (2009) 1.61
Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers. J Biol Chem (2009) 1.60
Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy. J Biol Chem (1998) 1.55
Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation. Prog Lipid Res (2007) 1.52
Secreted phospholipase A2 revisited. J Biochem (2011) 1.52
Mechanism and components of endoplasmic reticulum-associated degradation. J Biochem (2009) 1.48
Prostaglandin biosynthesis and its compartmentation in vascular smooth muscle and endothelial cells. Annu Rev Physiol (1986) 1.47
The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system. J Biol Chem (2006) 1.44
Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J Biol Chem (1994) 1.40
Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways. J Biol Chem (1999) 1.36
Structural basis of fatty acid substrate binding to cyclooxygenase-2. J Biol Chem (2010) 1.33
Intracellular localization and in vivo trafficking of p24A and p23. J Cell Sci (1999) 1.31
Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer. J Biol Chem (2011) 1.31
Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. Arthritis Res Ther (2004) 1.29
Two distinct pathways for cyclooxygenase-2 protein degradation. J Biol Chem (2008) 1.26
Molecular basis of sugar recognition by the human L-type lectins ERGIC-53, VIPL, and VIP36. J Biol Chem (2007) 1.23
N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum. J Biol Chem (1993) 1.21
Structure and function of beta -1,4-galactosyltransferase. Curr Drug Targets (2008) 1.20
Prostaglandin H synthase: resolved and unresolved mechanistic issues. Arch Biochem Biophys (2009) 1.18
Subcellular localization of prostaglandin-forming cyclooxygenase in Swiss mouse 3T3 fibroblasts by electron microscopic immunocytochemistry. J Biol Chem (1980) 1.18
Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts. J Biol Chem (2001) 1.12
Selective inhibition of prostaglandin endoperoxide synthase-1 (cyclooxygenase-1) by valerylsalicylic acid. Arch Biochem Biophys (1995) 1.11
The orientation of prostaglandin endoperoxide synthases-1 and -2 in the endoplasmic reticulum. J Biol Chem (1994) 1.11
Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to non-membrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes, and neutrophils. J Histochem Cytochem (1992) 1.10
Prostaglandin H synthase. Stoichiometry of heme cofactor. J Biol Chem (1984) 1.08
Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system. Mol Biol Cell (2011) 1.08
The role of MRH domain-containing lectins in ERAD. Glycobiology (2010) 1.07
Carbohydrate- and conformation-dependent cargo capture for ER-exit. Mol Biol Cell (2005) 1.05
The cytosolic phospholipase A2 catalytic domain modulates association and residence time at Golgi membranes. J Biol Chem (2003) 1.04
The membrane binding domains of prostaglandin endoperoxide H synthases 1 and 2. Peptide mapping and mutational analysis. J Biol Chem (1999) 1.03
Human cyclooxygenase-1 activity and its responses to COX inhibitors are allosterically regulated by nonsubstrate fatty acids. J Lipid Res (2012) 1.02
Glycosylation-independent ERAD pathway serves as a backup system under ER stress. Mol Biol Cell (2013) 1.01
Localization and function of cytosolic phospholipase A2alpha at the Golgi. Biochimie (2010) 1.01
The sugar-binding ability of ERGIC-53 is enhanced by its interaction with MCFD2. Blood (2007) 1.00
Macrophages induce COX-2 expression in breast cancer cells: role of IL-1β autoamplification. Carcinogenesis (2011) 0.98
Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn. Pharmacol Rev (2012) 0.97
On the evolutionary origin of cyclooxygenase (COX) isozymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. J Biol Chem (2004) 0.92
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer. J Biol Chem (2013) 0.92
An off-on COX-2-specific fluorescent probe: targeting the Golgi apparatus of cancer cells. J Am Chem Soc (2013) 0.91
Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex. J Biol Chem (2013) 0.88
Direct evidence of the cyclooxygenase pathway of prostaglandin synthesis in arthropods: genetic and biochemical characterization of two crustacean cyclooxygenases. Insect Biochem Mol Biol (2009) 0.87
Prostaglandin EP1 receptor down-regulates expression of cyclooxygenase-2 by facilitating its proteasomal degradation. J Biol Chem (2012) 0.85
Fever, inflammation, pain and beyond: prostanoid receptor research during these 25 years. FASEB J (2011) 0.85
The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells. J Biol Chem (2011) 0.85
Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells. Mol Biol Cell (2013) 0.84
Different substrate utilization between prostaglandin endoperoxide H synthase-1 and -2 in NIH3T3 fibroblasts. Biochim Biophys Acta (1998) 0.83
Two pathways for cyclooxygenase-2 protein degradation in vivo. J Biol Chem (2009) 0.83
Regulation of Mac-2BP secretion is mediated by its N-glycan binding to ERGIC-53. Glycobiology (2013) 0.79
Photolabeling of prostaglandin endoperoxide H synthase-1 with 3-trifluoro-3-(m-[125I]iodophenyl)diazirine as a probe of membrane association and the cyclooxygenase active site. J Biol Chem (1996) 0.79
Insulin-induced gene protein (INSIG)-dependent sterol regulation of Hmg2 endoplasmic reticulum-associated degradation (ERAD) in yeast. J Biol Chem (2013) 0.79