Genetic architecture of white matter hyperintensities differs in hypertensive and nonhypertensive ischemic stroke.

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Published in Stroke on December 30, 2014

Authors

Poneh Adib-Samii1, William Devan2, Matthew Traylor2, Silvia Lanfranconi2, Cathy R Zhang2, Lisa Cloonan2, Guido J Falcone2, Farid Radmanesh2, Kaitlin Fitzpatrick2, Allison Kanakis2, Peter M Rothwell2, Cathie Sudlow2, Giorgio B Boncoraglio2, James F Meschia2, Chris Levi2, Martin Dichgans2, Steve Bevan2, Jonathan Rosand2, Natalia S Rost2, Hugh S Markus2

Author Affiliations

1: From the Neuroscience Research Centre, Cardiovascular & Cell Sciences, St. George's University of London, London, United Kingdom (P.A.-S., S.L.); Department of Neurology, Center for Human Genetic Research, Massachusetts General Hospital, Boston (W.D., C.R.Z., L.C., G.J.F., F.R., K.F., A.K., J.R., N.S.R.); Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (M.T., S.B., H.S.M.); Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (F.R., J.R.); Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, Oxford, United Kingdom (P.M.R.); Division of Clinical Neurosciences, Neuroimaging Sciences, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom (C.S.); Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy (G.B.B.); Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Centre for Clinical Epidemiology and Biostatistics, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (C.L.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University Munich, Munich, Germany (M.D.); and Munich Cluster for Systems Neurology (SyNergy), Center for Stroke and Dementia Research, Munich, Germany (M.D.). padibsam@sgul.ac.uk.
2: From the Neuroscience Research Centre, Cardiovascular & Cell Sciences, St. George's University of London, London, United Kingdom (P.A.-S., S.L.); Department of Neurology, Center for Human Genetic Research, Massachusetts General Hospital, Boston (W.D., C.R.Z., L.C., G.J.F., F.R., K.F., A.K., J.R., N.S.R.); Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom (M.T., S.B., H.S.M.); Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (F.R., J.R.); Stroke Prevention Research Unit, Nuffield Department of Neuroscience, University of Oxford, Oxford, United Kingdom (P.M.R.); Division of Clinical Neurosciences, Neuroimaging Sciences, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom (C.S.); Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy (G.B.B.); Department of Neurology, Mayo Clinic, Jacksonville, FL (J.F.M.); Centre for Clinical Epidemiology and Biostatistics, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia (C.L.); Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University Munich, Munich, Germany (M.D.); and Munich Cluster for Systems Neurology (SyNergy), Center for Stroke and Dementia Research, Munich, Germany (M.D.).

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