|
1
|
Genome-wide genetic association of complex traits in heterogeneous stock mice.
|
Nat Genet
|
2006
|
9.87
|
|
2
|
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
Nat Genet
|
2012
|
7.59
|
|
3
|
Progress and prospects in rat genetics: a community view.
|
Nat Genet
|
2008
|
6.01
|
|
4
|
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice.
|
Proc Natl Acad Sci U S A
|
2006
|
5.19
|
|
5
|
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.
|
Anal Chem
|
2005
|
4.14
|
|
6
|
Genetic and environmental effects on complex traits in mice.
|
Genetics
|
2006
|
3.27
|
|
7
|
SNP and haplotype mapping for genetic analysis in the rat.
|
Nat Genet
|
2008
|
2.96
|
|
8
|
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.
|
Mamm Genome
|
2006
|
1.96
|
|
9
|
Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes.
|
Proc Natl Acad Sci U S A
|
2007
|
1.84
|
|
10
|
Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models.
|
Nat Genet
|
2007
|
1.66
|
|
11
|
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat.
|
Cell
|
2013
|
1.53
|
|
12
|
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.
|
Nat Genet
|
2013
|
1.30
|
|
13
|
The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man.
|
Diabetes
|
2002
|
1.28
|
|
14
|
Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.
|
PLoS One
|
2008
|
1.23
|
|
15
|
Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.
|
J Am Soc Nephrol
|
2005
|
1.22
|
|
16
|
Genome-wide diversity in the levant reveals recent structuring by culture.
|
PLoS Genet
|
2013
|
1.20
|
|
17
|
Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart.
|
Cardiovasc Res
|
2004
|
1.15
|
|
18
|
Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition.
|
Obesity (Silver Spring)
|
2008
|
1.14
|
|
19
|
A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock.
|
Genome Res
|
2008
|
1.13
|
|
20
|
MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes.
|
BMC Med Genomics
|
2009
|
1.10
|
|
21
|
Large scale association analysis identifies three susceptibility loci for coronary artery disease.
|
PLoS One
|
2011
|
1.07
|
|
22
|
Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations.
|
J Am Soc Nephrol
|
2007
|
1.07
|
|
23
|
Analysis of 14 candidate genes for diabetic nephropathy on chromosome 3q in European populations: strongest evidence for association with a variant in the promoter region of the adiponectin gene.
|
Diabetes
|
2006
|
1.06
|
|
24
|
Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles.
|
Diabetes
|
2010
|
1.06
|
|
25
|
Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis.
|
PLoS One
|
2012
|
1.03
|
|
26
|
Polygenic control of idiopathic generalized epilepsy phenotypes in the genetic absence rats from Strasbourg (GAERS).
|
Epilepsia
|
2004
|
1.03
|
|
27
|
Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart.
|
J Mol Cell Cardiol
|
2004
|
0.98
|
|
28
|
G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes.
|
Diabetes
|
2008
|
0.96
|
|
29
|
European rational approach for the genetics of diabetic complications--EURAGEDIC: patient populations and strategy.
|
Nephrol Dial Transplant
|
2007
|
0.96
|
|
30
|
Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes.
|
BMC Genomics
|
2009
|
0.96
|
|
31
|
Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome.
|
Diabetes
|
2004
|
0.95
|
|
32
|
Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome.
|
PLoS One
|
2008
|
0.95
|
|
33
|
The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex.
|
Eur J Immunol
|
2005
|
0.94
|
|
34
|
Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome.
|
PLoS One
|
2013
|
0.91
|
|
35
|
Integration of the rat recombination and EST maps in the rat genomic sequence and comparative mapping analysis with the mouse genome.
|
Genome Res
|
2004
|
0.90
|
|
36
|
Thymectomy and radiation-induced type 1 diabetes in nonlymphopenic BB rats.
|
Diabetes
|
2002
|
0.88
|
|
37
|
Mapping diabetes QTL in an intercross derived from a congenic strain of the Brown Norway and Goto-Kakizaki rats.
|
Mamm Genome
|
2006
|
0.86
|
|
38
|
Marker-assisted congenic screening (MACS): a database tool for the efficient production and characterization of congenic lines.
|
Mamm Genome
|
2003
|
0.86
|
|
39
|
Quantitative trait locus dissection in congenic strains of the Goto-Kakizaki rat identifies a region conserved with diabetes loci in human chromosome 1q.
|
Physiol Genomics
|
2004
|
0.86
|
|
40
|
Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains.
|
Am J Physiol Heart Circ Physiol
|
2004
|
0.86
|
|
41
|
Characterization of a major modifier locus for polycystic kidney disease (Modpkdr1) in the Han:SPRD(cy/+) rat in a region conserved with a mouse modifier locus for Alport syndrome.
|
Hum Mol Genet
|
2002
|
0.84
|
|
42
|
Genetic and environmental influences on total plasma homocysteine and its role in coronary artery disease risk.
|
Atherosclerosis
|
2012
|
0.84
|
|
43
|
Glycomics investigation into insulin action.
|
Biochim Biophys Acta
|
2006
|
0.83
|
|
44
|
Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus.
|
BMC Med Genomics
|
2009
|
0.83
|
|
45
|
Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine.
|
AIDS
|
2015
|
0.83
|
|
46
|
Studies of congenic lines in the Brown Norway rat model of Th2-mediated immunopathological disorders show that the aurothiopropanol sulfonate-induced immunological disorder (Aiid3) locus on chromosome 9 plays a major role compared to Aiid2 on chromosome 10.
|
J Immunol
|
2004
|
0.82
|
|
47
|
Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase.
|
J Proteome Res
|
2011
|
0.81
|
|
48
|
Broad-ranging natural metabotype variation drives physiological plasticity in healthy control inbred rat strains.
|
J Proteome Res
|
2011
|
0.80
|
|
49
|
Circulating lipid levels and risk of coronary artery disease in a large group of patients undergoing coronary angiography.
|
J Thromb Thrombolysis
|
2015
|
0.79
|
|
50
|
Genomic organization of the rat Clock gene and sequence analysis in inbred rat strains.
|
Genomics
|
2006
|
0.79
|
|
51
|
Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.
|
J Med Genet
|
2007
|
0.79
|
|
52
|
mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles.
|
Anal Chem
|
2015
|
0.78
|
|
53
|
Genetics and functional genomics of type 2 diabetes mellitus.
|
Genome Biol
|
2003
|
0.78
|
|
54
|
Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant.
|
Ann Nutr Metab
|
2015
|
0.78
|
|
55
|
Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: a possible link between ACE genotype and diabetic nephropathy.
|
Diabetes
|
2004
|
0.77
|
|
56
|
Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat.
|
Eur J Med Genet
|
2008
|
0.77
|
|
57
|
Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat.
|
Mamm Genome
|
2010
|
0.76
|
|
58
|
[Genetic mapping of metabolic profiles: genomic and metagenomic influences].
|
Med Sci (Paris)
|
2007
|
0.75
|
|
59
|
[Genome sequencing and genetic mapping to dissect the genetic basis of complex traits].
|
Med Sci (Paris)
|
2013
|
0.75
|