Identification of the target DNA sequence and characterization of DNA binding features of HlyU, and suggestion of a redox switch for hlyA expression in the human pathogen Vibrio cholerae from in silico studies.

Comparison of multiple Amber force fields and development of improved protein backbone parameters. Proteins (2006) 22.80

3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures. Nucleic Acids Res (2003) 10.63

Molecular epidemiology of Vibrio cholerae in the U.S. Gulf Coast. J Clin Microbiol (1982) 6.34

Defining the structure of irregular nucleic acids: conventions and principles. J Biomol Struct Dyn (1989) 5.52

Cholera and other vibrioses in the United States. N Engl J Med (1985) 5.17

Dissecting protein-protein recognition sites. Proteins (2002) 4.51

Origins of specificity in protein-DNA recognition. Annu Rev Biochem (2010) 4.43

Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector. Gene (1989) 4.41

Purification and characterization of a hemolysin produced by Vibrio cholerae biotype El Tor: another toxic substance produced by cholera vibrios. Infect Immun (1979) 2.99

Non-O1 Vibrio cholerae hemolysin: purification, partial characterization, and immunological relatedness to El Tor hemolysin. Infect Immun (1984) 2.72

Enterotoxicity of El Tor-like hemolysin of non-O1 Vibrio cholerae. Infect Immun (1987) 2.46

Vibrio cholerae Hcp, a secreted protein coregulated with HlyA. Infect Immun (1996) 2.25

Information-driven protein-DNA docking using HADDOCK: it is a matter of flexibility. Nucleic Acids Res (2006) 1.95

Epidemiological usefulness of changes in hemolytic activity of Vibrio cholerae biotype El Tor during the seventh pandemic. J Clin Microbiol (1981) 1.88

Anti-silencing: overcoming H-NS-mediated repression of transcription in Gram-negative enteric bacteria. Microbiology (2008) 1.84

The implementation of a fast and accurate QM/MM potential method in Amber. J Comput Chem (2008) 1.79

The transcriptional activator HlyU of Vibrio cholerae: nucleotide sequence and role in virulence gene expression. Mol Microbiol (1993) 1.65

The HlyU protein is a positive regulator of rtxA1, a gene responsible for cytotoxicity and virulence in the human pathogen Vibrio vulnificus. Infect Immun (2007) 1.55

Amino-terminal domain of the El Tor haemolysin of Vibrio cholerae O1 is expressed in classical strains and is cytotoxic. Vaccine (1991) 1.33

Vibrio cholerae anaerobic induction of virulence gene expression is controlled by thiol-based switches of virulence regulator AphB. Proc Natl Acad Sci U S A (2010) 1.29

Transcription of the Vibrio cholerae haemolysin gene, hlyA, and cloning of a positive regulatory locus, hlyU. Mol Microbiol (1991) 1.21

ProFace: a server for the analysis of the physicochemical features of protein-protein interfaces. BMC Struct Biol (2006) 1.19

Preselection of hemolytic variants of el tor vibrios. J Bacteriol (1966) 1.12

Interresidue contacts in proteins and protein-protein interfaces and their use in characterizing the homodimeric interface. J Proteome Res (2005) 1.02

HlyU acts as an H-NS antirepressor in the regulation of the RTX toxin gene essential for the virulence of the human pathogen Vibrio vulnificus CMCP6. Mol Microbiol (2009) 1.02

Anaerobiosis and low specific growth rates enhance hemolysin BL production by Bacillus cereus F4430/73. Arch Microbiol (2004) 1.01

Anaerobic growth promotes synthesis of colonization factors encoded at the Vibrio pathogenicity island in Vibrio cholerae El Tor. Res Microbiol (2008) 1.00

Vibrio cholerae HlyA hemolysin is processed by proteolysis. Infect Immun (1990) 0.99

Plant pathogenic bacteria utilize biofilm growth-associated repressor (BigR), a novel winged-helix redox switch, to control hydrogen sulfide detoxification under hypoxia. J Biol Chem (2011) 0.99

Environmental regulation of alpha-haemolysin expression in Escherichia coli. Microb Pathog (1994) 0.98

Multiple regulatory systems in Vibrio cholerae pathogenesis. Trends Microbiol (1994) 0.93

HELANAL-Plus: a web server for analysis of helix geometry in protein structures. J Biomol Struct Dyn (2012) 0.91

Molecular modeling and characterization of Vibrio cholerae transcription regulator HlyU. BMC Struct Biol (2006) 0.89

Vibrio cholerae O1 isolated in Kenya. J Clin Microbiol (1982) 0.88

HlyU is a positive regulator of hemolysin expression in Vibrio anguillarum. J Bacteriol (2011) 0.85

H-NS is a negative regulator of the two hemolysin/cytotoxin gene clusters in Vibrio anguillarum. Infect Immun (2013) 0.85

The regulator HlyU, the repeat-in-toxin gene rtxA1, and their roles in the pathogenesis of Vibrio vulnificus infections. Microbiologyopen (2012) 0.80

Homodimerization and binding of specific domains to the target DNA are essential requirements for HlyU to regulate expression of the virulence gene rtxA1, encoding the repeat-in-toxin protein in the human pathogen Vibrio vulnificus. J Bacteriol (2011) 0.78

Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications. Biochim Biophys Acta (2014) 0.78