Published in Org Biomol Chem on March 14, 2015
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest (2003) 5.32
Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors. Bioorg Med Chem (2005) 3.38
Biosensing using porous silicon double-layer interferometers: reflective interferometric Fourier transform spectroscopy. J Am Chem Soc (2005) 2.56
Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem (2005) 2.28
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem (2005) 1.92
Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem (2002) 1.86
Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res (2006) 1.75
The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells. FEBS J (2006) 1.68
Antitumour metal compounds: more than theme and variations. Dalton Trans (2007) 1.64
Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex. J Biol Chem (2006) 1.64
Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers. Hypertension (2010) 1.55
Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology. Chem Rev (2006) 1.55
Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity. J Med Chem (2009) 1.51
Redox status of acute pancreatitis as measured by cyclic voltammetry: initial rodent studies to assess disease severity. Crit Care Med (2008) 1.39
Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition (2008) 1.35
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J Biol Chem (2004) 1.33
Anticancer activity of metal complexes: involvement of redox processes. Antioxid Redox Signal (2011) 1.32
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism. Proc Natl Acad Sci U S A (2006) 1.27
Reflective interferometric fourier transform spectroscopy: a self-compensating label-free immunosensor using double-layers of porous SiO2. J Am Chem Soc (2006) 1.27
Molecules derived from the extremes of life. Nat Prod Rep (2009) 1.27
Transcriptomic analysis of the cardiac left ventricle in a rodent model of diabetic cardiomyopathy: molecular snapshot of a severe myocardial disease. Physiol Genomics (2006) 1.21
Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid. Biochem J (2003) 1.20
Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver. J Immunol Methods (2008) 1.13
The ruthenium(II)-arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53-JNK pathways. J Biol Inorg Chem (2008) 1.11
Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. Dalton Trans (2006) 1.10
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. PLoS One (2009) 1.10
Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1. J Biol Chem (2003) 1.10
Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations. Arch Toxicol (2011) 1.10
Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats. Proteomics (2008) 1.08
An internal fluorescent probe based on anthracene to evaluate cation-anion interactions in imidazolium salts. Chemistry (2010) 1.07
Spiroimine shellfish poisoning (SSP) and the spirolide family of shellfish toxins: isolation, structure, biological activity and synthesis. Nat Prod Rep (2010) 1.06
Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes. J Inorg Biochem (2010) 1.04
Forensic application of the luminol reaction as a presumptive test for latent blood detection. Talanta (2007) 1.02
Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells. J Anal At Spectrom (2009) 1.01
Randomized controlled crossover study of the effect of a highly beta-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men. Am J Clin Nutr (2003) 1.00
The proteome of rodent mesenteric lymph. Am J Physiol Gastrointest Liver Physiol (2008) 1.00
Altered calcium homeostasis does not explain the contractile deficit of diabetic cardiomyopathy. Diabetes (2008) 0.99
An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia. J Lipid Res (2008) 0.97
Changes in the mesenteric lymph proteome induced by hemorrhagic shock. Shock (2010) 0.97
Redox-active antineoplastic ruthenium complexes with indazole: correlation of in vitro potency and reduction potential. J Med Chem (2005) 0.97
A proteomic approach identifies early pregnancy biomarkers for preeclampsia: novel linkages between a predisposition to preeclampsia and cardiovascular disease. Proteomics (2009) 0.96
Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J Mol Biol (2002) 0.96
Proteomic characterization of human serum proteins associated with the fat-derived hormone adiponectin. Proteomics (2006) 0.96
Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds. J Med Chem (2008) 0.95
Isolation, biological activity and synthesis of benzannulated spiroketal natural products. Nat Prod Rep (2010) 0.94
Characterization of proteomic changes in cardiac mitochondria in streptozotocin-diabetic rats using iTRAQ™ isobaric tags. Proteomics Clin Appl (2007) 0.94
A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core. Chemistry (2011) 0.92
Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds. J Biol Inorg Chem (2012) 0.92
Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study. Anticancer Drugs (2009) 0.91
Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum. Proteomics (2004) 0.91
Synthesis of the bis-spiroacetal moiety of the shellfish toxins spirolides B and D using an iterative oxidative radical cyclization strategy. Org Biomol Chem (2006) 0.91
Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1H)-pyridones to biomolecules the anticancer activity determining parameter? Inorg Chem (2010) 0.90
Identification of novel putative membrane proteins selectively expressed during adipose conversion of 3T3-L1 cells. Biochem Biophys Res Commun (2002) 0.90
The proteome of mesenteric lymph during acute pancreatitis and implications for treatment. JOP (2009) 0.90
Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes (2007) 0.90
Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3-L1 adipocytes. FEBS Lett (2004) 0.90
Structure and dynamics of human Nedd4-1 WW3 in complex with the αENaC PY motif. Biochim Biophys Acta (2013) 0.90
C-H functionalization in the synthesis of amino acids and peptides. Chem Rev (2014) 0.89
CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP. J Inorg Biochem (2007) 0.89
Synthesis of the C10-C22 bis-spiroacetal domain of spirolides B and D via iterative oxidative radical cyclization. Org Lett (2002) 0.89
Synthesis of the ABC fragment of the pectenotoxins. Org Lett (2005) 0.89
(1R,6R)-1-Methyl-8-aza-spiro-[5.6]dodecan-7-one. Acta Crystallogr Sect E Struct Rep Online (2008) 0.89
Proteins associated with immunopurified granules from a model pancreatic islet beta-cell system: proteomic snapshot of an endocrine secretory granule. J Proteome Res (2009) 0.89
Digital microfluidics and delivery of molecular payloads with magnetic porous silicon chaperones. Dalton Trans (2007) 0.89
A novel approach to the CDE ring system of pectenotoxin-4 triggered by VO(acac)(2)-induced epoxy-acetalization. Org Lett (2009) 0.89
Phosphite-derivatized ruthenium-carbohydrate complexes in the catalytic hydration of nitriles. short communication. Chem Biodivers (2008) 0.88
Inhibition of bleach-induced luminol chemiluminescence. J Forensic Sci (2003) 0.88
Synthesis of fish antifreeze neoglycopeptides using microwave-assisted "click chemistry". Org Lett (2009) 0.88
Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats. Mol Pharmacol (2006) 0.88
A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin? ChemMedChem (2007) 0.88
Determination of triethylenetetramine (TETA) and its metabolites in human plasma and urine by liquid chromatography-mass spectrometry (LC-MS). J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.87
Platinum metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: characterization of interactions between Pt(II) complexes and human serum albumin. Electrophoresis (2004) 0.87
Multiplexed DNA detection using spectrally encoded porous SiO2 photonic crystal particles. Anal Chem (2009) 0.87
Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice. Diabetes (2009) 0.87
Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma. Electrophoresis (2008) 0.87
Comparative solution equilibrium studies of anticancer gallium(III) complexes of 8-hydroxyquinoline and hydroxy(thio)pyrone ligands. J Inorg Biochem (2012) 0.87
Protecting-group-free one-pot synthesis of glycoconjugates directly from reducing sugars. Angew Chem Int Ed Engl (2014) 0.86
The serum protein binding of pharmacologically active gallium(III) compounds assessed by hyphenated CE-MS techniques. Electrophoresis (2009) 0.86
Osmium(II)--versus ruthenium(II)--arene carbohydrate-based anticancer compounds: similarities and differences. Dalton Trans (2010) 0.86
Reversal of diabetes-evoked changes in mitochondrial protein expression of cardiac left ventricle by treatment with a copper(II)-selective chelator. Proteomics Clin Appl (2007) 0.86
Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy. Dalton Trans (2007) 0.86
High resolution mass spectrometry for studying the interactions of cisplatin with oligonucleotides. Inorg Chem (2008) 0.86
Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds. Inorg Chem (2012) 0.85
Thiol reducing compounds prevent human amylin-evoked cytotoxicity. FEBS J (2005) 0.85
Synthesis of macrocyclic shellfish toxins containing spiroimine moieties. Nat Prod Rep (2007) 0.85
Use of a sonogashira-acetylide coupling strategy for the synthesis of the aromatic spiroketal skeleton of gamma-rubromycin. Org Lett (2003) 0.85
Extravasation of Pt-based chemotherapeutics - bioimaging of their distribution in resectates using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). Metallomics (2015) 0.85
The hydration of chloroacetonitriles catalyzed by mono- and dinuclear Ru(II)- and Os(II)-arene complexes. Chem Biodivers (2008) 0.85
Synthesis of methyl N-Boc-(2S,4R)-4-methylpipecolate. J Org Chem (2010) 0.85
Studies on the reactivity of organometallic Ru-, Rh- and Os-pta complexes with DNA model compounds. J Inorg Biochem (2007) 0.85
Combined endopeptidase inhibition and adrenomedullin in sheep with experimental heart failure. Hypertension (2002) 0.85
Elucidation of the interactions of an anticancer ruthenium complex in clinical trials with biomolecules utilizing capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry. Short communication. Chem Biodivers (2008) 0.85
Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies. J Biol Inorg Chem (2012) 0.84
Anticancer activity of methyl-substituted oxaliplatin analogs. Mol Pharmacol (2012) 0.84
Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic beta-cells. FEBS J (2006) 0.84
Synthesis of the bis-spiroacetal moiety of spirolides B and D. Org Lett (2005) 0.84
The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes. Electrophoresis (2010) 0.83