Published in Diabetes on September 30, 2009
Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils. J Biol Chem (2010) 0.96
Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin. Mol Neurodegener (2014) 0.93
Amylin uncovered: a review on the polypeptide responsible for type II diabetes. Biomed Res Int (2013) 0.89
Structural similarities and differences between amyloidogenic and non-amyloidogenic islet amyloid polypeptide (IAPP) sequences and implications for the dual physiological and pathological activities of these peptides. PLoS Comput Biol (2013) 0.86
Protein folding and aggregation into amyloid: the interference by natural phenolic compounds. Int J Mol Sci (2013) 0.81
Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes. PLoS One (2014) 0.80
The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: innocent bystanders or partners in a crime? Front Endocrinol (Lausanne) (2014) 0.76
Novel insights into amylin aggregation. Biotechnol Biotechnol Equip (2014) 0.75
Protein quality control in heart disease: using established drugs to target novel mechanisms. J Am Coll Cardiol (2010) 0.75
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Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes. Interface Focus (2017) 0.75
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Prevalence and clinicopathological characteristics of islet amyloid in chinese patients with type 2 diabetes. Diabetes (2003) 1.13
Design of peptide-based inhibitors of human islet amyloid polypeptide fibrillogenesis. J Mol Biol (2002) 1.11
Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1. J Biol Chem (2003) 1.10
Tetracycline affects abnormal properties of synthetic PrP peptides and PrP(Sc) in vitro. J Mol Biol (2000) 1.09
Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide. Diabetes (2002) 1.00
4'-iodo-4'-deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters. FASEB J (2003) 0.97
beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes. Diabetes (2000) 0.96
Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J Mol Biol (2002) 0.96
Fas-associated death receptor signaling evoked by human amylin in islet beta-cells. Diabetes (2007) 0.90
Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells. Biochem Biophys Res Commun (1998) 0.90
Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes. Diabetologia (2000) 0.86
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The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest (2003) 5.32
Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol (2012) 3.59
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell (2013) 3.13
Activation of natural regulatory T cells by IgG Fc-derived peptide "Tregitopes". Blood (2008) 2.50
Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes. J Biol Chem (2005) 2.28
Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nat Cell Biol (2007) 2.23
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner. J Biol Chem (2005) 1.92
Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas. J Pathol (2011) 1.91
Immunogenicity of protein therapeutics. Trends Immunol (2007) 1.90
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma. Cancer Discov (2013) 1.90
Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis. Gastroenterology (2010) 1.88
Impact of concordant and discordant bone marrow involvement on outcome in diffuse large B-cell lymphoma treated with R-CHOP. J Clin Oncol (2011) 1.86
Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. Potential role in the modulation of its insulin-sensitizing activity. J Biol Chem (2002) 1.86
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood (2013) 1.84
Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res (2006) 1.75
Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning. Development (2005) 1.75
Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins. Blood (2005) 1.71
Cloned transgenic cattle produce milk with higher levels of beta-casein and kappa-casein. Nat Biotechnol (2003) 1.70
The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells. FEBS J (2006) 1.68
Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes. Blood (2014) 1.64
Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex. J Biol Chem (2006) 1.64
Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers. Hypertension (2010) 1.55
Additive effect of pretransplant obesity, diabetes, and cardiovascular risk factors on outcomes after liver transplantation. Liver Transpl (2014) 1.53
Identification of an essential Francisella tularensis subsp. tularensis virulence factor. Infect Immun (2008) 1.50
Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial. Blood (2012) 1.49
Trophectoderm lineage determination in cattle. Dev Cell (2011) 1.48
B cells "transduced" with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAE. Clin Immunol (2011) 1.44
Simple quality improvement interventions reduce unnecessary intravascular device dwell time. Infect Control Hosp Epidemiol (2008) 1.40
Robust Fitting of a Weibull Model with Optional Censoring. Comput Stat Data Anal (2013) 1.39
Redox status of acute pancreatitis as measured by cyclic voltammetry: initial rodent studies to assess disease severity. Crit Care Med (2008) 1.39
Postprandial response of adiponectin, interleukin-6, tumor necrosis factor-alpha, and C-reactive protein to a high-fat dietary load. Nutrition (2008) 1.35
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J Biol Chem (2004) 1.33
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism. Proc Natl Acad Sci U S A (2006) 1.27
Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma. Blood (2014) 1.26
Francisella tularensis subsp. tularensis Schu S4 disulfide bond formation protein B, but not an RND-type efflux pump, is required for virulence. Infect Immun (2008) 1.23
Transcriptomic analysis of the cardiac left ventricle in a rodent model of diabetic cardiomyopathy: molecular snapshot of a severe myocardial disease. Physiol Genomics (2006) 1.21
Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid. Biochem J (2003) 1.20
Newly diagnosed diabetes mellitus after acute pancreatitis: a systematic review and meta-analysis. Gut (2013) 1.20
A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome. Free Radic Biol Med (2009) 1.19
Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site. Thromb Haemost (2004) 1.17
B-cell-delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells. Mol Ther (2010) 1.17
RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Curr Biol (2009) 1.16
The E3 ubiquitin ligase UBR5 is recurrently mutated in mantle cell lymphoma. Blood (2013) 1.15
Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases. J Immunol (2002) 1.15
Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo. Clin Immunol (2011) 1.14
Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver. J Immunol Methods (2008) 1.13
Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1. J Biol Chem (2003) 1.10
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities. PLoS One (2009) 1.10
Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands. J Biol Chem (2011) 1.09
Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats. Proteomics (2008) 1.08
Treatment of diabetes in NOD mice by gene transfer of Ig-fusion proteins into B cells: role of T regulatory cells. Cell Immunol (2006) 1.08
Regeneration of the heart in diabetes by selective copper chelation. Diabetes (2004) 1.04
A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP. Clin Immunol (2004) 1.01
Randomized controlled crossover study of the effect of a highly beta-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterolemic men. Am J Clin Nutr (2003) 1.00
Analysis of FOXO1 mutations in diffuse large B-cell lymphoma. Blood (2013) 1.00
Tolerance induction by gene transfer to lymphocytes. Curr Gene Ther (2007) 1.00
The proteome of rodent mesenteric lymph. Am J Physiol Gastrointest Liver Physiol (2008) 1.00
Altered calcium homeostasis does not explain the contractile deficit of diabetic cardiomyopathy. Diabetes (2008) 0.99
Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients. Genome Biol (2015) 0.99
Effect of B-cell depletion using anti-CD20 therapy on inhibitory antibody formation to human FVIII in hemophilia A mice. Blood (2010) 0.98
An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia. J Lipid Res (2008) 0.97
Mycobacterial Hsp65-IgG-expressing tolerogenic B cells confer protection against adjuvant-induced arthritis in Lewis rats. Arthritis Rheum (2007) 0.97
B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathway. J Immunol (2008) 0.97
Tregitope update: mechanism of action parallels IVIg. Autoimmun Rev (2012) 0.97
A role for thrombin in the initiation of the immune response to therapeutic factor VIII. Blood (2009) 0.97
Changes in the mesenteric lymph proteome induced by hemorrhagic shock. Shock (2010) 0.97
A proteomic approach identifies early pregnancy biomarkers for preeclampsia: novel linkages between a predisposition to preeclampsia and cardiovascular disease. Proteomics (2009) 0.96
Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J Mol Biol (2002) 0.96
Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor. Am J Surg Pathol (2008) 0.96
Proteomic characterization of human serum proteins associated with the fat-derived hormone adiponectin. Proteomics (2006) 0.96
In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity. J Clin Immunol (2012) 0.95
A cytosolic tRNA with an unmodified adenosine in the wobble position reads a codon ending with the non-complementary nucleoside cytidine. J Mol Biol (2002) 0.95
Characterization of proteomic changes in cardiac mitochondria in streptozotocin-diabetic rats using iTRAQ™ isobaric tags. Proteomics Clin Appl (2007) 0.94
Connexins in wound healing; perspectives in diabetic patients. Biochim Biophys Acta (2011) 0.94
Requirement of the CXXC motif of novel Francisella infectivity potentiator protein B FipB, and FipA in virulence of F. tularensis subsp. tularensis. PLoS One (2011) 0.93
A factorial analysis of the combined effects of hydrogel fabrication parameters on the in vitro swelling and degradation of oligo(poly(ethylene glycol) fumarate) hydrogels. J Biomed Mater Res A (2013) 0.93
Mechanisms of gene therapy for tolerance: B7 signaling is required for peptide-IgG gene-transferred tolerance induction. J Immunol (2005) 0.93
Factor VIII inhibitors: risk factors and methods for prevention and immune modulation. Clin Rev Allergy Immunol (2009) 0.92
Early nasogastric tube feeding versus nil per os in mild to moderate acute pancreatitis: a randomized controlled trial. Clin Nutr (2012) 0.92
Proteomic and functional characterization of endogenous adiponectin purified from fetal bovine serum. Proteomics (2004) 0.91
Overexpression of the gap junction protein Cx43 as found in diabetic foot ulcers can retard fibroblast migration. Cell Biol Int (2012) 0.91
Tolerance induction via a B-cell delivered gene therapy-based protocol: optimization and role of the Ig scaffold. Cell Immunol (2005) 0.91
Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLoS One (2012) 0.90
Putative stem cells in human dental pulp with irreversible pulpitis: an exploratory study. J Endod (2010) 0.90
B-Cell Gene Therapy for Tolerance Induction: Host but Not Donor B-Cell Derived IL-10 is Necessary for Tolerance. Front Microbiol (2011) 0.90
Chronic treatment with growth hormone stimulates adiponectin gene expression in 3T3-L1 adipocytes. FEBS Lett (2004) 0.90