Population pharmacokinetic modeling of plasma and intracellular ribavirin concentrations in patients with chronic hepatitis C virus infection.

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Published in Antimicrob Agents Chemother on February 02, 2015

Authors

Liviawati S Wu1, Joseph E Rower2, James R Burton3, Peter L Anderson2, Kyle P Hammond2, Fafa Baouchi-Mokrane4, Gregory T Everson3, Thomas J Urban5, David Z D'Argenio1, Jennifer J Kiser6

Author Affiliations

1: University of Southern California, Biomedical Engineering, Los Angeles, CA, USA.
2: University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Aurora, Colorado, USA.
3: University of Colorado School of Medicine, Division of Gastroenterology and Hepatology, Aurora, Colorado, USA.
4: Denver Health Medical Center, Denver, Colorado, USA.
5: Duke University, Durham, North Carolina, USA.
6: University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences, Aurora, Colorado, USA Jennifer.Kiser@ucdenver.edu.

Associated clinical trials:

Concentration-Controlled Ribavirin for the Treatment of Patients With Chronic Hepatitis C Virus Infection | NCT01097395

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