Function of metabolic and organelle networks in crowded and organized media.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4300868)

Published in Front Physiol on January 21, 2015

Authors

Miguel A Aon1, Sonia Cortassa1

Author Affiliations

1: Department of Medicine, School of Medicine, Johns Hopkins University Baltimore, MD, USA.

Articles cited by this

Protein complexes and functional modules in molecular networks. Proc Natl Acad Sci U S A (2003) 9.03

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences. Annu Rev Biophys (2008) 7.77

Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. Int Rev Cytol (2000) 6.61

Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med (2000) 5.90

The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media. J Biol Chem (2001) 5.57

Macromolecular architecture in eukaryotic cells visualized by cryoelectron tomography. Science (2002) 5.28

Probing the structure of cytoplasm. J Cell Biol (1986) 5.10

Complexes of sequential metabolic enzymes. Annu Rev Biochem (1987) 4.99

Macromolecular crowding: an important but neglected aspect of the intracellular environment. Curr Opin Struct Biol (2001) 4.27

Amplification and adaptation in regulatory and sensory systems. Science (1982) 4.19

Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J Biol Chem (2003) 3.93

Diffusion, crowding & protein stability in a dynamic molecular model of the bacterial cytoplasm. PLoS Comput Biol (2010) 3.65

The concept of self-organization in cellular architecture. J Cell Biol (2001) 3.49

Phase transitions in the assembly of multivalent signalling proteins. Nature (2012) 3.49

VDAC: the channel at the interface between mitochondria and the cytosol. Mol Cell Biochem (2004) 3.26

Implications of macromolecular crowding for protein assembly. Curr Opin Struct Biol (2000) 3.20

Solute and macromolecule diffusion in cellular aqueous compartments. Trends Biochem Sci (2002) 3.18

Crowding effects on diffusion in solutions and cells. Annu Rev Biophys (2008) 3.00

Properties and metabolism of the aqueous cytoplasm and its boundaries. Am J Physiol (1984) 2.89

Biomolecular dynamics and binding studies in the living cell. Phys Life Rev (2013) 2.70

Reaction kinetics in intracellular environments with macromolecular crowding: simulations and rate laws. Prog Biophys Mol Biol (2004) 2.40

Percolation and criticality in a mitochondrial network. Proc Natl Acad Sci U S A (2004) 2.17

Sensitivity amplification in biochemical systems. Q Rev Biophys (1982) 2.16

VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function. Biophys J (1997) 2.09

Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration. Proc Natl Acad Sci U S A (2008) 2.06

Fractal reaction kinetics. Science (1988) 2.05

Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev (2014) 1.96

On the role of organized multienzyme systems in cellular metabolism: a general synthesis. Prog Biophys Mol Biol (1977) 1.86

Monte carlo simulations of enzyme reactions in two dimensions: fractal kinetics and spatial segregation. Biophys J (2002) 1.84

High-resolution mapping of intracellular fluctuations using carbon nanotubes. Science (2014) 1.81

From protoplasmic theory to cellular systems biology: a 150-year reflection. Am J Physiol Cell Physiol (2010) 1.79

Intracellular water and the cytomatrix: some methods of study and current views. J Cell Biol (1984) 1.72

The pentose phosphate pathway and cancer. Trends Biochem Sci (2014) 1.65

The fundamental organization of cardiac mitochondria as a network of coupled oscillators. Biophys J (2006) 1.55

A reaction-diffusion model of ROS-induced ROS release in a mitochondrial network. PLoS Comput Biol (2010) 1.47

Molecular evolution, intracellular organization, and the quinary structure of proteins. Proc Natl Acad Sci U S A (1982) 1.45

A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria. Antioxid Redox Signal (2006) 1.40

Generation and maintenance of synchrony in Saccharomyces cerevisiae continuous culture. Exp Cell Res (2003) 1.39

Mechanical effects of neurofilament cross-bridges. Modulation by phosphorylation, lipids, and interactions with F-actin. J Biol Chem (1996) 1.37

Life in a crowded world. EMBO Rep (2004) 1.33

Influence of excluded volume upon macromolecular structure and associations in 'crowded' media. Curr Opin Biotechnol (1997) 1.30

Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding. Biophys Chem (2003) 1.30

Glutathione oxidation as a trigger of mitochondrial depolarization and oscillation in intact hearts. J Mol Cell Cardiol (2008) 1.27

On the possible role of cytoskeletal filamentous networks in intracellular signaling: an approach based on percolation. J Cell Sci (1995) 1.26

From mitochondrial dynamics to arrhythmias. Int J Biochem Cell Biol (2009) 1.26

Michaelis-Menten mechanism reconsidered: implications of fractal kinetics. J Theor Biol (1995) 1.23

Effect of macromolecular crowding on reaction rates: a computational and theoretical study. Biophys J (2009) 1.21

Macromolecular compartmentation and channeling. Int Rev Cytol (2000) 1.21

Regulation of cell function by the cellular hydration state. Am J Physiol (1994) 1.19

Spatial patterns from oscillating microtubules. Science (1989) 1.17

Self-organization in the genome. Proc Natl Acad Sci U S A (2009) 1.17

The fractal architecture of cytoplasmic organization: scaling, kinetics and emergence in metabolic networks. Mol Cell Biochem (2004) 1.11

Self-similarity and fractal irregularity in pathologic tissues. Mod Pathol (1996) 1.11

Modest protein-crowder attractive interactions can counteract enhancement of protein association by intermolecular excluded volume interactions. J Phys Chem B (2011) 1.10

VDAC inhibition by tubulin and its physiological implications. Biochim Biophys Acta (2011) 1.08

Gravitational symmetry breaking in microtubular dissipative structures. Proc Natl Acad Sci U S A (1992) 1.06

Implications of macromolecular crowding for signal transduction and metabolite channeling. Proc Natl Acad Sci U S A (1998) 1.06

Atomic detail brownian dynamics simulations of concentrated protein solutions with a mean field treatment of hydrodynamic interactions. J Phys Chem B (2012) 1.02

The molecular biology of Euglena gracilis. IV. Cellular stratification by centrifuging. Exp Cell Res (1968) 0.98

Involvement of microtubules in the link between cell volume and pH of acidic cellular compartments in rat and human hepatocytes. Proc Natl Acad Sci U S A (1994) 0.98

The temporal architecture of eukaryotic growth. FEBS Lett (2006) 0.97

Mitochondria-cytoskeleton interaction: distribution of β-tubulins in cardiomyocytes and HL-1 cells. Biochim Biophys Acta (2011) 0.96

Criticality in intracellular calcium signaling in cardiac myocytes. Biophys J (2012) 0.95

Quinary protein structure and the consequences of crowding in living cells: leaving the test-tube behind. Bioessays (2013) 0.95

Microtubule oscillations. Cell Motil Cytoskeleton (1992) 0.94

Single and cell population respiratory oscillations in yeast: a 2-photon scanning laser microscopy study. FEBS Lett (2006) 0.94

Effect of hepatocyte swelling on microtubule stability and tubulin mRNA levels. Biochem Cell Biol (1994) 0.93

The role of phosphorylation in the interaction of rabbit muscle phosphofructokinase with F-actin. J Biol Chem (1986) 0.93

On the fractal nature of cytoplasm. FEBS Lett (1994) 0.92

The shape of protein crowders is a major determinant of protein diffusion. Biophys J (2013) 0.92

Physiological environment induces quick response - slow exhaustion reactions. Front Physiol (2011) 0.92

Using fractals and nonlinear dynamics to determine the physical properties of ion channel proteins. Crit Rev Neurobiol (1996) 0.92

Effect of crowding by dextrans on the hydrolysis of N-Succinyl-L-phenyl-Ala-p-nitroanilide catalyzed by α-chymotrypsin. J Phys Chem B (2010) 0.90

Binding of phosphofructokinase to filamentous actin. Biochemistry (1987) 0.89

Effect of crowding by dextrans and Ficolls on the rate of alkaline phosphatase-catalyzed hydrolysis: a size-dependent investigation. Biopolymers (2006) 0.88

Effects of stress on cellular infrastructure and metabolic organization in plant cells Int Rev Cytol (2000) 0.87

Redox rhythmicity: clocks at the core of temporal coherence. Bioessays (2007) 0.87

Biochemistry. Enzyme kinetics, past and present. Science (2013) 0.85

Diffusion within the cytoplasm: a mesoscale model of interacting macromolecules. Biophys J (2014) 0.85

Characterization of microtubule-associated protein MAP1B: phosphorylation state, light chains, and binding to microtubules. Biochemistry (1996) 0.84

Effect of crowding by Dextrans in enzymatic reactions. Biophys Chem (2013) 0.84

Observation of a chaotic multioscillatory metabolic attractor by real-time monitoring of a yeast continuous culture. FEBS J (2007) 0.83

Microtubular protein in its polymerized or nonpolymerized states differentially modulates in vitro and intracellular fluxes catalyzed by enzymes of carbon metabolism. J Cell Biochem (1994) 0.83

Studies of the role of tubulin beta II isotype in regulation of mitochondrial respiration in intracellular energetic units in cardiac cells. J Mol Cell Cardiol (2011) 0.82

Alternative binding of two sequential glycolytic enzymes to microtubules. Molecular studies in the phosphofructokinase/aldolase/microtubule system. J Biol Chem (1997) 0.82

Phase transitions, interfaces, and morphogenesis in a network of protein fibers. Int Rev Cytol (1994) 0.82

Spatio-temporal regulation of glycolysis and oxidative phosphorylation in vivo in tumor and yeast cells. Cell Biol Int (1994) 0.82

Self-organizing actomyosin patterns on the cell cortex at epithelial cell-cell junctions. Biophys J (2014) 0.82

Interactions of aminoacyl-tRNA synthetases in high-molecular-weight multienzyme complexes from rat liver. Biochim Biophys Acta (1985) 0.81

Modulation of urokinase-type plasminogen activator and metalloproteinase activities in cultured mouse mammary-carcinoma cells: enhancement by paclitaxel and inhibition by nocodazole. Int J Cancer (1999) 0.80

Coherent and robust modulation of a metabolic network by cytoskeletal organization and dynamics. Biophys Chem (2002) 0.79

Fueled by microtubules: does tubulin dimer/polymer partitioning regulate intracellular metabolism? Cytoskeleton (Hoboken) (2012) 0.78

Fractal-like kinetics of intracellular enzymatic reactions: a chemical framework of endotoxin tolerance and a possible non-specific contribution of macromolecular crowding to cross-tolerance. Theor Biol Med Model (2013) 0.77

The supramolecular organization of ovomucin. Biophysical and morphological studies. Biochem J (1990) 0.77

Modeling of sensing potency of cytoskeletal systems decorated with metabolic enzymes. J Theor Biol (2014) 0.76

Ultrasensitivity in (supra)molecularly organized and crowded environments. Cell Biol Int (2001) 0.76

Heterogeneous distribution and organization of cytoskeletal proteins drive differential modulation of metabolic fluxes. J Cell Biochem (1996) 0.75

Fractal organisation in biological macromolecular lattices. J Biomol Struct Dyn (1992) 0.75