Published in Cell on May 05, 1989
The human HOX gene family. Nucleic Acids Res (1989) 3.13
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J (1990) 2.97
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes. Proc Natl Acad Sci U S A (1995) 2.65
Pbx modulation of Hox homeodomain amino-terminal arms establishes different DNA-binding specificities across the Hox locus. Mol Cell Biol (1996) 2.48
Hox specificity unique roles for cofactors and collaborators. Curr Top Dev Biol (2009) 2.37
Eukaryotic transcription factors. Biochem J (1990) 2.16
Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins. Mol Cell Biol (1993) 2.12
Coordinate regulation of HOX genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1991) 1.88
Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body. EMBO J (1991) 1.88
Hoxc13 mutant mice lack external hair. Genes Dev (1998) 1.84
HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities. EMBO J (1991) 1.70
Low affinity binding site clusters confer hox specificity and regulatory robustness. Cell (2014) 1.64
Analysis of homologous gene clusters in Caenorhabditis elegans reveals striking regional cluster domains. Genetics (2005) 1.55
Detection of homeobox genes in development and evolution. Proc Natl Acad Sci U S A (1991) 1.55
Expansion of the Hox gene family and the evolution of chordates. Proc Natl Acad Sci U S A (1993) 1.52
The expression pattern of a Drosophila homolog to the mouse transcription factor HNF-4 suggests a determinative role in gut formation. EMBO J (1993) 1.52
Targeted replacement of the homeobox gene Hox-3.1 by the Escherichia coli lacZ in mouse chimeric embryos. Proc Natl Acad Sci U S A (1990) 1.42
Structural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complex. Mol Cell Biol (1996) 1.40
Identification of positive and negative regulatory elements governing cell-type-specific expression of the neural cell adhesion molecule gene. Mol Cell Biol (1990) 1.34
HOM/HOX homeobox genes are present in hydra (Chlorohydra viridissima) and are differentially expressed during regeneration. EMBO J (1992) 1.29
High-frequency germ line gene conversion in transgenic mice. Mol Cell Biol (1992) 1.29
Conservation of the organization of five tightly clustered genes over 600 million years of divergent evolution. Proc Natl Acad Sci U S A (1992) 1.26
Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10. Mol Cell Biol (2003) 1.26
Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster. Mol Cell Biol (1994) 1.25
Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia. EMBO J (1992) 1.23
The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins. EMBO J (1992) 1.19
Binding and transcriptional activation of the promoter for the neural cell adhesion molecule by HoxC6 (Hox-3.3). Proc Natl Acad Sci U S A (1993) 1.16
The Antennapedia-type homeobox genes have evolved from three precursors separated early in metazoan evolution. Proc Natl Acad Sci U S A (1993) 1.15
Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif. Nucleic Acids Res (1996) 1.10
Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers. PLoS One (2011) 1.06
Relationship of eukaryotic DNA replication to committed gene expression: general theory for gene control. Microbiol Rev (1991) 1.06
Evolutionary conservation of the structure and expression of alternatively spliced Ultrabithorax isoforms from Drosophila. Genetics (1994) 1.06
Tempo and mode in evolution of transcriptional regulation. PLoS Genet (2012) 1.05
The expression of murine Hox-2 genes is dependent on the differentiation pathway and displays a collinear sensitivity to retinoic acid in F9 cells and Xenopus embryos. Nucleic Acids Res (1991) 1.04
Coordinated spatial and temporal expression of Hox genes during embryogenesis in the acoel Convolutriloba longifissura. BMC Biol (2009) 1.02
The role of the Hoxa10/HOXA10 gene in the etiology of endometriosis and its related infertility: a review. J Assist Reprod Genet (2010) 1.02
Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes. EMBO J (1994) 1.01
A retinoic acid-triggered cascade of HOXB1 gene activation. Proc Natl Acad Sci U S A (1995) 0.98
Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7. Nucleic Acids Res (1991) 0.97
A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma. Epigenetics (2013) 0.96
Modulation of homeobox gene expression alters the phenotype of human hematopoietic cell lines. EMBO J (1992) 0.96
Homeobox genes in the ribbonworm Lineus sanguineus: evolutionary implications. Proc Natl Acad Sci U S A (1998) 0.95
Correlation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer. Breast Cancer Res (2003) 0.95
Functional dissection of the mouse Hox-a5 gene. EMBO J (1996) 0.94
A yeast artificial chromosome containing the mouse homeobox cluster Hox-2. Proc Natl Acad Sci U S A (1990) 0.93
Repression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residues. Mol Cell Biol (1996) 0.92
Establishment of tribolium as a genetic model system and its early contributions to evo-devo. Genetics (2008) 0.92
Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells. Mol Cell Biol (1991) 0.91
Differential DNA binding properties of three human homeodomain proteins. Nucleic Acids Res (1992) 0.90
Genome and transcriptome of the regeneration-competent flatworm, Macrostomum lignano. Proc Natl Acad Sci U S A (2015) 0.87
The molecular anatomy of Hox gene expression. J Anat (1994) 0.87
Cloning and expression of a new HOXC6 transcript encoding a repressing protein. Biochem J (1996) 0.87
A distinct class of homeodomain proteins is encoded by two sequentially expressed Drosophila genes from the 93D/E cluster. Nucleic Acids Res (1994) 0.84
Functional hierarchy and phenotypic suppression among Drosophila homeotic genes: the labial and empty spiracles genes. EMBO J (1996) 0.84
Secondary DNA structure formation for Hoxb9 promoter and identification of its specific binding protein. Nucleic Acids Res (2008) 0.84
Coral comparative genomics reveal expanded Hox cluster in the cnidarian-bilaterian ancestor. Integr Comp Biol (2012) 0.82
Possible role of DNA topoisomerase II on transcription of the homeobox gene Hox-2.1 in F9 embryonal carcinoma cells. Nucleic Acids Res (1991) 0.82
Hox genes, evo-devo, and the case of the ftz gene. Chromosoma (2015) 0.81
Spatial organization of genes as a component of regulated expression. Chromosoma (2009) 0.80
The evo-devo comet. EMBO Rep (2010) 0.77
A novel role for the AAA ATPase spastin as a HOXA10 transcriptional corepressor in Ishikawa endometrial cells. Mol Endocrinol (2011) 0.77
Temporal transcription of two antennapedia class homeobox genes in the marine copepod Calanus helgolandicus. Mar Biotechnol (NY) (2003) 0.76
Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife (2016) 0.76
A new paradigm for animal symmetry. Interface Focus (2015) 0.76
Michael Akam and the rise of evolutionary developmental biology. Int J Dev Biol (2010) 0.75
Epigenetic Interactions and Gene Expression in Peri-Implantation Mouse Embryo Development. Mod Cell Biol (1) 0.75
Hox genes and evolution. F1000Res (2016) 0.75
Clustered brachiopod Hox genes are not expressed collinearly and are associated with lophotrochozoan novelties. Proc Natl Acad Sci U S A (2017) 0.75
Closely related DNA sequences specify distinct patterns of developmental expression in Drosophila melanogaster. Mol Cell Biol (1990) 0.75