Yusu Gu

Author PubWeight™ 72.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 MicroRNA-133 controls cardiac hypertrophy. Nat Med 2007 11.68
2 ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med 2002 3.36
3 Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A 2002 3.18
4 Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci U S A 2002 3.13
5 Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest 2009 2.98
6 Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med 2002 2.37
7 An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest 2008 2.19
8 Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog. J Clin Invest 2005 2.19
9 MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest 2010 2.04
10 The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem 2001 1.99
11 Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res 2010 1.85
12 Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest 2014 1.82
13 Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest 2012 1.59
14 Myocardial expression, signaling, and function of GPR22: a protective role for an orphan G protein-coupled receptor. Am J Physiol Heart Circ Physiol 2008 1.53
15 Nesprin 1 is critical for nuclear positioning and anchorage. Hum Mol Genet 2009 1.48
16 Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function. J Clin Invest 2011 1.46
17 Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats. J Clin Invest 2004 1.33
18 Muscle-specific VEGF deficiency greatly reduces exercise endurance in mice. J Physiol 2009 1.32
19 alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture. Circulation 2006 1.28
20 Prion-induced amyloid heart disease with high blood infectivity in transgenic mice. Science 2006 1.23
21 The cardiovascular physiologic actions of urocortin II: acute effects in murine heart failure. Proc Natl Acad Sci U S A 2004 1.22
22 Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death. Hum Mol Genet 2008 1.22
23 Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest 2008 1.18
24 Restoration of deficient membrane proteins in the cardiomyopathic hamster by in vivo cardiac gene transfer. Circulation 2002 1.14
25 Sarcoplasmic reticulum calcium defect in Ras-induced hypertrophic cardiomyopathy heart. Am J Physiol Heart Circ Physiol 2003 1.11
26 Ca2+/Calmodulin-dependent protein kinase II δ mediates myocardial ischemia/reperfusion injury through nuclear factor-κB. Circ Res 2013 1.08
27 Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse. Endocrinology 2009 1.07
28 Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction. PLoS One 2011 1.06
29 Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res 2011 1.05
30 erbB2 is required for G protein-coupled receptor signaling in the heart. Proc Natl Acad Sci U S A 2006 0.95
31 Delta-sarcoglycan gene therapy halts progression of cardiac dysfunction, improves respiratory failure, and prolongs life in myopathic hamsters. Circ Heart Fail 2010 0.93
32 Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Hum Mol Genet 2011 0.92
33 Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development. Dev Biol 2006 0.92
34 Apoptosis and oncosis in the early progression of left ventricular dysfunction in the cardiomyopathic hamster. Basic Res Cardiol 2002 0.92
35 β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses. Am J Pathol 2012 0.91
36 Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse. Circulation 2007 0.89
37 Gene transfer of a phospholamban-targeted antibody improves calcium handling and cardiac function in heart failure. Cardiovasc Res 2005 0.89
38 Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem 2012 0.89
39 Syncoilin is required for generating maximum isometric stress in skeletal muscle but dispensable for muscle cytoarchitecture. Am J Physiol Cell Physiol 2008 0.87
40 Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model. Hum Mol Genet 2013 0.87
41 Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias. Circulation 2011 0.85
42 Normalization of Naxos plakoglobin levels restores cardiac function in mice. J Clin Invest 2015 0.84
43 Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation. J Appl Physiol (1985) 2013 0.81
44 Pulmonary artery pressure responses to increased cardiac output in chickens with raised metabolic rate. Comp Biochem Physiol A Mol Integr Physiol 2010 0.78
45 A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. FASEB J 2004 0.76
46 Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice. J Appl Physiol (1985) 2013 0.76
47 Analysis and validation of traits associated with a single nucleotide polymorphism Gly364Ser in catestatin using humanized chromogranin A mouse models. J Hypertens 2016 0.75
48 Impaired chronotropic response to exercise in mice lacking catecholamines in adrenergic cells. Ann N Y Acad Sci 2008 0.75