Early postnatal ablation of the microRNA-processing enzyme, Drosha, causes chondrocyte death and impairs the structural integrity of the articular cartilage.

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🔗 View Article (PMID 25707934)

Published in Osteoarthritis Cartilage on February 21, 2015

Authors

T Kobayashi¹, G Papaioannou², F Mirzamohammadi³, E Kozhemyakina⁴, M Zhang⁵, R Blelloch⁶, M W Chong⁷

Author Affiliations

1: Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: tkobayashi1@mgh.harvard.edu.
2: Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: GPAPAIOANNOU@mgh.harvard.edu.
3: Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: FMIRZAMOHAMMADI@mgh.harvard.edu.
4: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: eKozhemyakina@dresourcesgroup.com.
5: Department of Orthopaedic Surgery, Boston Children's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: Minjie.Zhang@childrens.harvard.edu.
6: The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: blellochr@stemcell.ucsf.edu.
7: Genomics and Immunology Laboratory, St. Vincent's Institute of Medical Research, and Department of Medicine, University of Melbourne, Fitzroy, VIC 3065, Australia. Electronic address: mchong@svi.edu.au.

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