In vivo evaluation of the dentate gate theory in epilepsy.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMID 25752305)

Published in J Physiol on March 31, 2015

Authors

Esther Krook-Magnuson1, Caren Armstrong1, Anh Bui1, Sean Lew1, Mikko Oijala1, Ivan Soltesz1

Author Affiliations

1: Department of Anatomy and Neurobiology, University of California, Irvine, USA.

Articles citing this

Closed-loop and activity-guided optogenetic control. Neuron (2015) 1.42

Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Sci Data (2017) 1.37

Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy. J Neurosci (2016) 0.93

Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures. Nat Commun (2016) 0.84

Normal and epilepsy-associated pathologic function of the dentate gyrus. Prog Brain Res (2016) 0.83

Organization and control of epileptic circuits in temporal lobe epilepsy. Prog Brain Res (2016) 0.82

Optogenetic Approaches for Controlling Seizure Activity. Brain Stimul (2016) 0.78

Target-selectivity of parvalbumin-positive interneurons in layer II of medial entorhinal cortex in normal and epileptic animals. Hippocampus (2016) 0.78

Seizing Control: From Current Treatments to Optogenetic Interventions in Epilepsy. Neuroscientist (2015) 0.77

Cognitive Collaborations: Bidirectional Functional Connectivity Between the Cerebellum and the Hippocampus. Front Syst Neurosci (2015) 0.76

Optogenetic study of networks in epilepsy. J Neurosci Res (2016) 0.76

The Gate and the Source? The Dentate Gyrus Takes Central Stage in Temporal Lobe Epilepsy. Epilepsy Curr (2017) 0.75

Conditional Disabled-1 Deletion in Mice Alters Hippocampal Neurogenesis and Reduces Seizure Threshold. Front Neurosci (2016) 0.75

Abnormal UP/DOWN Membrane Potential Dynamics Coupled with the Neocortical Slow Oscillation in Dentate Granule Cells during the Latent Phase of Temporal Lobe Epilepsy. eNeuro (2016) 0.75

High Pressure and [Ca (2+) ] Produce an Inverse Modulation of Synaptic Input Strength and Network Excitability in the Rat Dentate Gyrus. Front Cell Neurosci (2016) 0.75

Massively augmented hippocampal dentate granule cell activation accompanies epilepsy development. Sci Rep (2017) 0.75

Ictal Activity Swimming Upstream in the Temporal Lobe. Epilepsy Curr (2016) 0.75

Homeostasis or channelopathy? Acquired cell type-specific ion channel changes in temporal lobe epilepsy and their antiepileptic potential. Front Physiol (2015) 0.75

Applications of optogenetic and chemogenetic methods to seizure circuits: Where to go next? J Neurosci Res (2017) 0.75

Axonal sprouting in commissurally projecting parvalbumin-expressing interneurons. J Neurosci Res (2017) 0.75

Rabies Tracing of Birthdated Dentate Granule Cells in Rat Temporal Lobe Epilepsy. Ann Neurol (2017) 0.75

Chemically activated luminopsins allow optogenetic inhibition of distributed nodes in an epileptic network for non-invasive and multi-site suppression of seizure activity. Neurobiol Dis (2017) 0.75

Sustained efficacy of closed loop electrical stimulation for long-term treatment of absence epilepsy in rats. Sci Rep (2017) 0.75

PTEN deletion increases hippocampal granule cell excitability in male and female mice. Neurobiol Dis (2017) 0.75

Articles cited by this

Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr Clin Neurophysiol (1972) 16.34

Pattern separation in the dentate gyrus and CA3 of the hippocampus. Science (2007) 8.49

Subregion- and cell type-restricted gene knockout in mouse brain. Cell (1996) 8.02

Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network. Science (2007) 6.48

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing. Nat Neurosci (2012) 4.87

GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus. J Neurosci (1998) 3.63

Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy. Sci Transl Med (2012) 3.53

The anatomy of memory: an interactive overview of the parahippocampal-hippocampal network. Nat Rev Neurosci (2009) 3.22

Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo. Nat Neurosci (2002) 2.83

Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: final results of the RNS System Pivotal trial. Epilepsia (2014) 2.60

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy. Nat Commun (2013) 2.39

Optogenetic control of epileptiform activity. Proc Natl Acad Sci U S A (2009) 2.24

Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy. Neuron (2012) 2.17

Reduced inhibition of dentate granule cells in a model of temporal lobe epilepsy. J Neurosci (2003) 2.09

Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy. J Neurosci (2007) 2.00

Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy. J Neurosci (2011) 1.93

The dentate gyrus as a regulated gate for the propagation of epileptiform activity. Epilepsy Res Suppl (1992) 1.90

Electrophysiologic analysis of a chronic seizure model after unilateral hippocampal KA injection. Epilepsia (1999) 1.83

Massive and specific dysregulation of direct cortical input to the hippocampus in temporal lobe epilepsy. J Neurosci (2006) 1.71

A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsy. Nat Neurosci (2011) 1.66

The dentate gyrus as a control point for seizures in the hippocampus and beyond. Epilepsy Res Suppl (1992) 1.59

Genetic architecture of the mouse hippocampus: identification of gene loci with selective regional effects. Genes Brain Behav (2003) 1.54

The input-output transformation of the hippocampal granule cells: from grid cells to place fields. J Neurosci (2009) 1.51

Can we reconcile the declarative memory and spatial navigation views on hippocampal function? Neuron (2014) 1.48

Functional regulation of the dentate gyrus by GABA-mediated inhibition. Prog Brain Res (2007) 1.37

Space in the brain: how the hippocampal formation supports spatial cognition. Philos Trans R Soc Lond B Biol Sci (2013) 1.36

A revised Racine's scale for PTZ-induced seizures in rats. Physiol Behav (2009) 1.32

Cerebellar Directed Optogenetic Intervention Inhibits Spontaneous Hippocampal Seizures in a Mouse Model of Temporal Lobe Epilepsy. eNeuro (2014) 1.17

Entorhinal cortex entrains epileptiform activity in CA1 in pilocarpine-treated rats. Neurobiol Dis (2005) 1.16

Hippocampal microcircuit dynamics probed using optical imaging approaches. J Physiol (2011) 1.14

Neurogliaform cells in the molecular layer of the dentate gyrus as feed-forward γ-aminobutyric acidergic modulators of entorhinal-hippocampal interplay. J Comp Neurol (2011) 1.14

Closed-loop optogenetic intervention in mice. Nat Protoc (2013) 1.12

Accumulation of abnormal adult-generated hippocampal granule cells predicts seizure frequency and severity. J Neurosci (2013) 1.09

Long-term effects of intrahippocampal kainic acid injection in rats: a method for inducing spontaneous recurrent seizures. Electroencephalogr Clin Neurophysiol (1982) 1.09

Early loss of interneurons and delayed subunit-specific changes in GABA(A)-receptor expression in a mouse model of mesial temporal lobe epilepsy. Hippocampus (2000) 1.08

Increased excitatory synaptic input to granule cells from hilar and CA3 regions in a rat model of temporal lobe epilepsy. J Neurosci (2012) 1.08

Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy model. PLoS One (2013) 0.99

Global optogenetic activation of inhibitory interneurons during epileptiform activity. J Neurosci (2014) 0.99

Rates of motor seizure development in rats subjected to electrical brain stimulation: strain and inter-stimulation interval effects. Electroencephalogr Clin Neurophysiol (1973) 0.99

Protracted postnatal development of sparse, specific dentate granule cell activation in the mouse hippocampus. J Neurosci (2013) 0.97

Chronic epileptogenic cellular alterations in the limbic system after status epilepticus. Epilepsia (1999) 0.97

Deep brain stimulation for epilepsy. Handb Clin Neurol (2013) 0.97

Loss and reacquisition of hippocampal synapses after selective destruction of CA3-CA4 afferents with kainic acid. Brain Res (1980) 0.97

Neurogliaform and Ivy Cells: A Major Family of nNOS Expressing GABAergic Neurons. Front Neural Circuits (2012) 0.95

Experimental epileptogenesis: kindling-induced epilepsy in rats. Exp Neurol (1978) 0.94

Optogenetic inhibition of chemically induced hypersynchronized bursting in mice. Neurobiol Dis (2014) 0.94

Long- and short-term plasticity at mossy fiber synapses on mossy cells in the rat dentate gyrus. Hippocampus (2005) 0.93

Seizure suppression by high frequency optogenetic stimulation using in vitro and in vivo animal models of epilepsy. Brain Stimul (2014) 0.92

How might novel technologies such as optogenetics lead to better treatments in epilepsy? Adv Exp Med Biol (2014) 0.91

Adaptive intrinsic plasticity in human dentate gyrus granule cells during temporal lobe epilepsy. Cereb Cortex (2011) 0.87

The electrophysiology of dentate gyrus granule cells in whole-cell recordings. Epilepsy Res Suppl (1992) 0.83

Role of dentate gyrus alterations in mesial temporal sclerosis. Clin Neuropathol (2009) 0.83

Septotemporal position in the hippocampal formation determines epileptic and neurogenic activity in temporal lobe epilepsy. Cereb Cortex (2011) 0.83

Entorhinal cortex-hippocampal interactions in normal and epileptic temporal lobe. Hippocampus (1993) 0.80

Extratemporal lobe circuits in temporal lobe epilepsy. Epilepsy Behav (2014) 0.78