Published in Transcription on January 01, 2014
Ligand-dependent enhancer activation regulated by topoisomerase-I activity. Cell (2015) 1.74
Roles of eukaryotic topoisomerases in transcription, replication and genomic stability. Nat Rev Mol Cell Biol (2016) 1.05
APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer. Cell Rep (2015) 0.88
The Dynamic Interplay Between DNA Topoisomerases and DNA Topology. Biophys Rev (2016) 0.81
The dynamic interplay between DNA topoisomerases and DNA topology. Biophys Rev (2016) 0.75
DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression. Biophys Rev (2016) 0.75
Controlling gene expression by DNA mechanics: emerging insights and challenges. Biophys Rev (2016) 0.75
DNA supercoiling is a fundamental regulatory principle in the control of bacterial gene expression. Biophys Rev (2016) 0.75
Controlling gene expression by DNA mechanics: emerging insights and challenges. Biophys Rev (2016) 0.75
Large-Scale Conformational Transitions in Supercoiled DNA Revealed by Coarse-Grained Simulation. Biophys J (2016) 0.75
Physiological functions of programmed DNA breaks in signal-induced transcription. Nat Rev Mol Cell Biol (2017) 0.75
Supercoiling of the DNA template during transcription. Proc Natl Acad Sci U S A (1987) 14.25
Transcription generates positively and negatively supercoiled domains in the template. Cell (1988) 5.73
The functional response of upstream DNA to dynamic supercoiling in vivo. Nat Struct Mol Biol (2008) 3.90
Transcription-driven supercoiling of DNA: direct biochemical evidence from in vitro studies. Cell (1989) 3.00
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner. Nature (2007) 2.64
Linking RNA polymerase backtracking to genome instability in E. coli. Cell (2011) 2.20
Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures. Nat Struct Mol Biol (2013) 2.09
Transcription-dependent dynamic supercoiling is a short-range genomic force. Nat Struct Mol Biol (2013) 2.07
Direct observation of DNA rotation during transcription by Escherichia coli RNA polymerase. Nature (2001) 2.06
Promoter unwinding and promoter clearance by RNA polymerase: detection by single-molecule DNA nanomanipulation. Proc Natl Acad Sci U S A (2004) 1.81
The dynamic response of upstream DNA to transcription-generated torsional stress. Nat Struct Mol Biol (2004) 1.74
Structural plasticity of single chromatin fibers revealed by torsional manipulation. Nat Struct Mol Biol (2006) 1.74
Transcription under torsion. Science (2013) 1.54
Formation of nucleosomes on positively supercoiled DNA. EMBO J (1991) 1.50
E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase. J Mol Biol (2010) 1.36
Positive supercoiling of DNA greatly diminishes mRNA synthesis in yeast. Proc Natl Acad Sci U S A (1992) 1.35
Large-scale effects of transcriptional DNA supercoiling in vivo. J Mol Biol (1999) 1.31
Underwound DNA under tension: structure, elasticity, and sequence-dependent behaviors. Phys Rev Lett (2011) 1.30
Cellular strategies for regulating DNA supercoiling: a single-molecule perspective. Cell (2010) 1.25
The problem of hypernegative supercoiling and R-loop formation in transcription. Front Biosci (2003) 1.21
Effect of varying the supercoiling of DNA on transcription and its regulation. Biochemistry (2003) 1.12
Visualization of unconstrained negative supercoils of DNA on polytene chromosomes of Drosophila. J Cell Sci (2004) 1.11
Transcriptional coupling between the divergent promoters of a prototypic LysR-type regulatory system, the ilvYC operon of Escherichia coli. Proc Natl Acad Sci U S A (1999) 1.09
Local DNA topology and gene expression: the case of the leu-500 promoter. Mol Microbiol (1991) 1.07
Torque modulates nucleosome stability and facilitates H2A/H2B dimer loss. Nat Commun (2013) 1.07
Transcription-coupled hypernegative supercoiling of plasmid DNA by T7 RNA polymerase in Escherichia coli topoisomerase I-deficient strains. J Mol Biol (2007) 1.02
The generation of promoter-mediated transcriptional noise in bacteria. PLoS Comput Biol (2008) 0.99
Torque spectroscopy of DNA: base-pair stability, boundary effects, backbending, and breathing dynamics. Phys Rev Lett (2013) 0.91
Underwinding of DNA on binding of yeast TFIID to the TATA element. Biochem Biophys Res Commun (1993) 0.84
Alanine-scanning mutagenesis defines a conserved energetic hotspot in the CaValpha1 AID-CaVbeta interaction site that is critical for channel modulation. Structure (2008) 1.17
Self-digitization of sample volumes. Anal Chem (2010) 1.05
Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase. Mol Cancer Ther (2009) 0.91
Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability. PLoS One (2010) 0.86
Trichomonas vaginalis infection in a premature newborn. J Perinatol (2002) 0.85
Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK). Transl Oncogenomics (2007) 0.79
A safe, effective, and facility compatible cleaning in place procedure for affinity resin in large-scale monoclonal antibody purification. J Chromatogr A (2013) 0.79
Pharmacokinetics of EDP-420 after ascending single oral doses in healthy adult volunteers. Antimicrob Agents Chemother (2009) 0.75
Head tracking in virtual reality displays reduces the misperception of 3D motion. J Vis (2015) 0.75