Published in N Engl J Med on July 11, 1985
The Effect of Omalizumab on Responses to Cat Allergen Challenge | NCT00604786
Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils. Proc Natl Acad Sci U S A (1991) 2.41
Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions. J Clin Invest (1989) 1.97
Effects of omalizumab on basophil and mast cell responses using an intranasal cat allergen challenge. J Allergy Clin Immunol (2009) 1.68
Monocyte chemotactic and activating factor is a potent histamine-releasing factor for basophils. J Clin Invest (1992) 1.66
Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a. Proc Natl Acad Sci U S A (1990) 1.30
Macrophage inflammatory protein-1 alpha activates basophils and mast cells. J Exp Med (1992) 1.27
Cutaneous late-phase response to allergen. Mediator release and inflammatory cell infiltration. J Clin Invest (1989) 1.23
Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J Clin Invest (1998) 1.20
Overview on the pathomechanisms of allergic rhinitis. Asia Pac Allergy (2011) 1.05
Reversibility and reproducibility of histamine induced plasma leakage in nasal airways. Thorax (1989) 1.03
Adherence of human basophils to cultured umbilical vein endothelial cells. J Clin Invest (1988) 0.96
Effect of short-term systemic glucocorticoid treatment on human nasal mediator release after antigen challenge. J Clin Invest (1987) 0.95
Histamine induces IL-6 production by human endothelial cells. Clin Exp Immunol (1994) 0.95
Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin. Am J Pathol (2009) 0.94
T lymphocytes and mast cells express messenger RNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis. Immunology (1994) 0.85
Comparative nasal effects of bradykinin and histamine: influence on nasal airways resistance and plasma protein exudation. Thorax (1993) 0.85
A competitive kinin receptor antagonist, [DArg0, Hyp3, DPhe7]-bradykinin, does not affect the response to nasal provocation with bradykinin. Br J Clin Pharmacol (1991) 0.84
Role of mast cells in the pathogenesis of hypersensitivity pneumonitis. Thorax (1987) 0.82
Conjunctival provocative tests: a model of human ocular allergy. Trans Am Ophthalmol Soc (1989) 0.82
The upper respiratory tract: mucous membrane irritation. Environ Health Perspect (1991) 0.81
Pharmacological and functional characterization of bradykinin receptors in canine cultured tracheal epithelial cells. Br J Pharmacol (1996) 0.81
Recombinant allergen-based provocation testing. Methods (2013) 0.80
Enhanced release of IgE-dependent early phase mediators from nasal polyp tissue. J Inflamm (Lond) (2009) 0.80
Risk multipliers for severe food anaphylaxis. World Allergy Organ J (2015) 0.80
Differences in airway inflammation according to atopic status in patients with chronic rhinitis. Asia Pac Allergy (2012) 0.79
Implication of the bradykinin receptors in antigen-induced pulmonary inflammation in mice. Br J Pharmacol (2003) 0.78
Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. Eur J Pharmacol (2015) 0.78
Allergic rhinoconjunctivitis: the role of histamine. Mediators Inflamm (1994) 0.77
Bradykinin stimulates MMP-2 production in guinea pig tracheal smooth muscle cells. Inflammation (2003) 0.77
Effect of an inhaled neutral endopeptidase inhibitor, phosphoramidon, on baseline airway calibre and bronchial responsiveness to bradykinin in asthma. Thorax (1995) 0.76
Effect of nedocromil sodium on antigen-induced airway responses in allergic sheep. Drugs (1989) 0.76
Mechanisms of nasal hyper-reactivity. Eur Arch Otorhinolaryngol (1995) 0.76
Pharmacological control of human basophil histamine release stimulated by eosinophil granule major basic protein. Immunology (1989) 0.76
Nasal responsiveness to allergen and histamine in patients with perennial rhinitis with and without a late phase response. Thorax (1997) 0.76
Immunology of allergic rhinitis, or a nose for treatment. J R Soc Med (1986) 0.75
The temporal relationship between the neural and vascular actions of kallidin within the nose. Mediators Inflamm (1993) 0.75
Stability of Syk protein and mRNA in human peripheral blood basophils. J Leukoc Biol (2016) 0.75
The release of IL-31 and IL-13 after nasal allergen challenge and their relation to nasal symptoms. Clin Transl Allergy (2012) 0.75
The role of nasal secretions in allergic disease of the nose. Arch Otorhinolaryngol (1989) 0.75
Human anaphylaxis. West J Med (1986) 0.75
Isolation and characterization of trypsin-like and chymotrypsin-like proteinases from human cholesteatoma. Eur Arch Otorhinolaryngol (1994) 0.75
Nasal hyperreactivity and inflammation in allergic rhinitis. Mediators Inflamm (1996) 0.75
Hyperresponsiveness in the human nasal airway: new targets for the treatment of allergic airway disease. Mediators Inflamm (1999) 0.75
Protective effects of deflazacort on allergen-specific conjunctival challenge. Eur J Clin Pharmacol (1993) 0.75
Implicating adhesion molecules in nasal allergic inflammation. Eur Arch Otorhinolaryngol (1995) 0.75
The pharmacology of airway hyperresponsiveness and inflammation. Lung (1990) 0.75
Linkage group I: the simultaneous estimation of recombination and interference. Birth Defects Orig Artic Ser (1976) 8.63
Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man. Proc Natl Acad Sci U S A (1983) 6.50
Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science (1996) 5.06
Ragweed immunotherapy in adult asthma. N Engl J Med (1996) 4.69
Histamine release in vitro: inhibition by catecholamines and methylxanthines. Science (1968) 4.38
Modulation of inflammation and immunity by cyclic AMP. Science (1974) 4.31
The role of cyclic 3',5' adenosine monophosphate in the specific cytolytic activity of lymphocytes. J Immunol (1972) 3.51
Evidence for individual human peripheral blood lymphocytes bearing both B and T cell markers. Nature (1974) 3.12
Genetic susceptibility to asthma--bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med (1995) 2.98
Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. J Immunol (1997) 2.91
Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med (2016) 2.89
Characteristics of prostate cancer in families potentially linked to the hereditary prostate cancer 1 (HPC1) locus. JAMA (1997) 2.73
Pharmacologic control of allergic histamine release in vitro: evidence for an inhibitory role of 3',5'-adenosine monophosphate in human leukocytes. J Immunol (1972) 2.70
A reappraisal of sting challenges: to whom should we offer venom immunotherapy? J Allergy Clin Immunol (1994) 2.65
Anaphylaxis. N Engl J Med (1991) 2.53
Histamine augments leukocyte adenosine 3',5'-monophosphate and blocks antigenic histamine release. Science (1971) 2.47
Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils. Proc Natl Acad Sci U S A (1991) 2.41
Insect sting allergy with negative venom skin test responses. J Allergy Clin Immunol (2001) 2.38
Mediator release after nasal airway challenge with allergen. Am Rev Respir Dis (1983) 2.37
The value of immunotherapy with venom in children with allergy to insect stings. N Engl J Med (1990) 2.35
A case for venom treatment in anaphylactic sensitivity to hymenoptera sting. N Engl J Med (1974) 2.33
Inhibition of histamine release by histamine controlled by H2 receptor. Nature (1973) 2.19
IL-13 expression at the sites of allergen challenge in patients with asthma. J Immunol (1995) 2.18
Immunological aspects of allergic asthma. Annu Rev Immunol (1994) 2.17
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
Discontinuing venom immunotherapy: outcome after five years. J Allergy Clin Immunol (1996) 2.13
The Stickler syndrome: evidence for close linkage to the structural gene for type II collagen. Genomics (1987) 2.11
Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet (1995) 2.09
A controlled trial of immunotherapy in insect hypersensitivity. N Engl J Med (1978) 2.08
Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity. J Allergy Clin Immunol (2000) 2.05
Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure. J Clin Invest (1995) 2.05
Kinins are generated in vivo following nasal airway challenge of allergic individuals with allergen. J Clin Invest (1983) 2.05
Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma. J Allergy Clin Immunol (1996) 2.03
The effects of the H1 and H2 antihistamines on "allergic" histamine release and its inhibition by histamine. J Pharmacol Exp Ther (1975) 2.02
Association of a promoter polymorphism of the CD14 gene and atopy. Am J Respir Crit Care Med (2001) 1.99
Histamine release from human leukocytes: studies with deuterium oxide, colchicine, and cytochalasin B. J Clin Invest (1972) 1.98
Molecular identification of an IgE-dependent histamine-releasing factor. Science (1995) 1.95
Effects of cholera toxin on in vitro models of immediate and delayed hypersensitivity. Further evidence for the role of cyclic adenosine 3',5'-monophosphate. J Clin Invest (1973) 1.94
Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. Am J Hum Genet (2000) 1.94
The immediate allergic response: in vitro separation of antigen activation, decay and histamine release. J Immunol (1971) 1.93
Ethnic differences in asthma and associated phenotypes: collaborative study on the genetics of asthma. J Allergy Clin Immunol (2001) 1.89
Anaphylactic release of thromboxane A2, prostaglandin D2, and prostacyclin from human lung parenchyma. Am Rev Respir Dis (1981) 1.86
Clinical and in vitro studies on the role of immunotherapy in ragweed hay fever. Am J Med (1968) 1.84
Epidemiology of insect venom sensitivity. JAMA (1989) 1.83
Immunologic and cellular changes accompanying the therapy of pollen allergy. J Clin Invest (1971) 1.80
Detection of tissue kallikrein in the bronchoalveolar lavage fluid of asthmatic subjects. J Clin Invest (1987) 1.80
Human lung mast cells: purification and characterization. J Immunol (1982) 1.78
The role of cyclic AMP in the cytolytic activity of lymphocytes. J Immunol (1971) 1.78
Generation of leukotrienes by purified human lung mast cells. J Clin Invest (1982) 1.77
The Marfan syndrome locus: confirmation of assignment to chromosome 15 and identification of tightly linked markers at 15q15-q21.3. Genomics (1991) 1.75
Evidence that autoimmunity in man is a Mendelian dominant trait. Am J Hum Genet (1986) 1.74
The immediate allergic response: in vitro action of cyclic AMP-active and other drugs on the two stages of histamine release. J Immunol (1971) 1.73
House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. J Allergy Clin Immunol (2001) 1.73
Release of slow reacting substance of anaphylaxis (SRS-A) from human leukocytes by the calcium ionophore A23187. J Immunol (1976) 1.72
IgE receptors on human basophils. Relationship to serum IgE concentration. J Clin Invest (1978) 1.71
IgE responses in human filariasis. I. Quantitation of filaria-specific IgE. J Immunol (1981) 1.71
Allergen immunotherapy: therapeutic vaccines for allergic diseases. World Health Organization. American academy of Allergy, Asthma and Immunology. Ann Allergy Asthma Immunol (1998) 1.70
Basophil "releasability" in patients with asthma. Am Rev Respir Dis (1980) 1.70
Lymphokine and cytokine production by Fc epsilon RI+ cells. Adv Immunol (1993) 1.67
The effects of a series of prostaglandins on in vitro models of the allergic response and cellular immunity. Prostaglandins (1972) 1.67
Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population. Am J Respir Cell Mol Biol (2001) 1.65
Physiologic manifestations of human anaphylaxis. J Clin Invest (1980) 1.65
Major genes regulating total serum immunoglobulin E levels in families with asthma. Am J Hum Genet (2000) 1.63
Studies on the mechanism of lymphocyte-mediated cytolysis. IV. Specificity of the histamine receptor on effector T cells. J Immunol (1973) 1.63
Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. Clin Exp Allergy (2001) 1.63
Measurement of IgE on human basophils: relation to serum IgE and anti-IgE-induced histamine release. J Immunol (1977) 1.63
Assessment of the biologic availability of tetracycline products in man. Clin Pharmacol Ther (1972) 1.62
Fetal hemoglobin levels in sickle cell disease and normal individuals are partially controlled by an X-linked gene located at Xp22.2. Blood (1992) 1.62
Association of protamine IgE and IgG antibodies with life-threatening reactions to intravenous protamine. N Engl J Med (1989) 1.62
Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population. JAMA (2000) 1.62
Patterns of maternal transmission in bipolar affective disorder. Am J Hum Genet (1995) 1.60
IgE antibody measurements in ragweed hay fever. Relationship to clinical severity and the results of immunotherapy. J Clin Invest (1973) 1.58
Routine use of penicillin skin testing on an inpatient service. N Engl J Med (1971) 1.58
Influence of clinical subtype, sex, and lineality on age at onset of major affective disorder in a family sample. Am J Psychiatry (1994) 1.58
Natural history of Hymenoptera venom sensitivity in adults. J Allergy Clin Immunol (1997) 1.55
Weight loss in mildly to moderately obese patients with obstructive sleep apnea. Ann Intern Med (1985) 1.55
Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma. Clin Exp Allergy (2004) 1.55