Published in Biology (Basel) on April 01, 2015
Age-related changes in Egr1 transcription and DNA methylation within the hippocampus. Hippocampus (2016) 0.80
H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. J Neurosci (2016) 0.78
Late enrichment maintains accurate recent and remote spatial memory only in aged rats that were unimpaired when middle aged. Learn Mem (2016) 0.75
Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation. Front Cell Neurosci (2017) 0.75
Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci U S A (1999) 8.83
Recovery of learning and memory is associated with chromatin remodelling. Nature (2007) 6.72
Altered histone acetylation is associated with age-dependent memory impairment in mice. Science (2010) 6.38
Regulation of histone acetylation during memory formation in the hippocampus. J Biol Chem (2004) 5.99
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur J Neurosci (2004) 4.64
Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci (2008) 3.86
Object recognition in rats and mice: a one-trial non-matching-to-sample learning task to study 'recognition memory'. Nat Protoc (2006) 3.71
Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci (2003) 3.33
Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience (2004) 2.81
Rapid and selective induction of BDNF expression in the hippocampus during contextual learning. Nat Neurosci (2000) 2.64
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci (2015) 2.43
The use of animal models to study the effects of aging on cognition. Annu Rev Psychol (1997) 2.32
Histone methylation regulates memory formation. J Neurosci (2010) 2.30
Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats. J Neurosci (2007) 1.86
Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience (2003) 1.83
Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol Aging (2010) 1.61
Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. J Neurosci (2009) 1.52
Histone demethylase LSD1 regulates neural stem cell proliferation. Mol Cell Biol (2010) 1.47
Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice. Neurobiol Aging (2003) 1.36
Spatial reference and working memory across the lifespan of male Fischer 344 rats. Neurobiol Aging (2007) 1.27
Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment. Hippocampus (2011) 1.20
G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation. J Neurosci (2012) 1.18
Hippocampal volume is preserved and fails to predict recognition memory impairment in aged rhesus monkeys (Macaca mulatta). Neurobiol Aging (2005) 1.17
Chromatin remodeling in the aging genome of Drosophila. Aging Cell (2010) 1.14
Control of synaptic consolidation in the dentate gyrus: mechanisms, functions, and therapeutic implications. Prog Brain Res (2007) 1.05
Brain-penetrant LSD1 inhibitors can block memory consolidation. ACS Chem Neurosci (2011) 1.04
Epigenetic mechanisms: critical contributors to long-term memory formation. Neuroscientist (2011) 1.02
Paradoxical role of an Egr transcription factor family member, Egr2/Krox20, in learning and memory. Front Behav Neurosci (2007) 1.01
Long-term exposure to environmental enrichment since youth prevents recognition memory decline and increases synaptic plasticity markers in aging. Neurobiol Learn Mem (2008) 1.00
Voluntary exercise induces adult hippocampal neurogenesis and BDNF expression in a rodent model of fetal alcohol spectrum disorders. Eur J Neurosci (2011) 0.96
Epigenetic modifications in the nervous system and their impact upon cognitive impairments. Neuropharmacology (2014) 0.95
Age-related memory impairment is associated with disrupted multivariate epigenetic coordination in the hippocampus. PLoS One (2012) 0.94
Epigenetic gene regulation in the adult mammalian brain: multiple roles in memory formation. Neurobiol Learn Mem (2011) 0.93
Region-specific genetic alterations in the aging hippocampus: implications for cognitive aging. Front Aging Neurosci (2010) 0.92
Histone lysine methylation: critical regulator of memory and behavior. Rev Neurosci (2013) 0.92
Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. Neuroscience (2013) 0.92
A new one-trial test for neurobiological studies of memory in rats. II: Effects of piracetam and pramiracetam. Behav Brain Res (1989) 0.89
Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals. Mech Ageing Dev (2011) 0.89
Epigenetic mechanisms of memory formation and reconsolidation. Neurobiol Learn Mem (2014) 0.85
Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan. Neurobiol Aging (2011) 0.83
Age-dependent effects of environmental enrichment on spatial memory and neurochemistry. Neurobiol Learn Mem (2014) 0.80
[Voluntary wheel running enhances cell proliferation and expression levels of BDNF, IGF1 and WNT4 in dentate gyrus of adult mice]. Sheng Li Xue Bao (2014) 0.77