Multiplex Ligation-dependent Probe Amplification Can Clarify HER2 Status in Gastric Cancers with "Polysomy 17".

PubWeight™: 0.79‹?›

🔗 View Article (PMC 4392047)

Published in J Cancer on February 26, 2015

Authors

Tao Wang1, Yutaka Amemiya2, Pauline Henry3, Arun Seth4, Wedad Hanna5, Eugene T Hsieh5

Author Affiliations

1: 1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada;
2: 2. Genomics Core Facilities, Sunnybrook Research Institute, Toronto, Canada;
3: 1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; ; 3. Department of Pathology, Toronto East General Hospital, Toronto, Canada;
4: 1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; ; 2. Genomics Core Facilities, Sunnybrook Research Institute, Toronto, Canada; ; 4. Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada.
5: 1. Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; ; 4. Department of Pathology, Sunnybrook Health Sciences Centre, Toronto, Canada.

Articles cited by this

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet (2010) 25.32

Recommendations for human epidermal growth factor receptor 2 testing in breast cancer: American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update. J Clin Oncol (2013) 12.57

Assessment of a HER2 scoring system for gastric cancer: results from a validation study. Histopathology (2008) 5.31

HER2 testing in gastric cancer: a practical approach. Mod Pathol (2012) 2.68

miR-21 microRNA expression in human gastric carcinomas and its clinical association. Anticancer Res (2008) 2.09

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nat Cell Biol (2005) 1.78

miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN. Toxicology (2013) 1.34

Molecular profiling of invasive breast cancer by multiplex ligation-dependent probe amplification-based copy number analysis of tumor suppressor and oncogenes. Mod Pathol (2010) 1.16

Absence of chromosome 17 polysomy in breast cancer: analysis by CEP17 chromogenic in situ hybridization and multiplex ligation-dependent probe amplification. Breast Cancer Res Treat (2009) 1.13

Topoisomerase IIalpha gene amplification in gastric carcinomas: correlation with the HER2 gene. An immunohistochemical, immunoblotting, and multicolor fluorescence in situ hybridization study. Hum Pathol (2006) 1.05

Determining true HER2 gene status in breast cancers with polysomy by using alternative chromosome 17 reference genes: implications for anti-HER2 targeted therapy. J Clin Oncol (2011) 1.05

Correlation between genomic alterations assessed by array comparative genomic hybridization, prognostically informative histologic subtype, stage, and patient survival in gastric cancer. Hum Pathol (2011) 1.02

Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients. BMC Cancer (2008) 1.02

Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer. Genomics (2007) 1.01

HER-2/neu amplification testing in breast cancer by Multiplex Ligation-dependent Probe Amplification: influence of manual- and laser microdissection. BMC Cancer (2009) 0.96

HIF1 regulates WSB-1 expression to promote hypoxia-induced chemoresistance in hepatocellular carcinoma cells. FEBS Lett (2013) 0.96

Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer. Mod Pathol (2009) 0.86

Expression screening of 17q12-21 amplicon reveals GRB7 as an ERBB2-dependent oncogene. FEBS Lett (2012) 0.83