Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.

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Published in J Neurosci on April 15, 2015

Authors

Amanda Ford1, Annie Castonguay2, Martin Cottet2, Joshua W Little3, Zhoumou Chen1, Ashley M Symons-Liguori4, Timothy Doyle1, Terrance M Egan1, Todd W Vanderah4, Yves De Konnick2, Dilip K Tosh5, Kenneth A Jacobson5, Daniela Salvemini6

Author Affiliations

1: Department of Pharmacological and Physiological Science, St. Louis University School of Medicine, St. Louis, Missouri 63104.
2: Institut Universitaire en Santé Mentale de Québec, Québec City, Quebec G1J 2G3, Canada, Department of Psychiatry & Neuroscience, Université Laval, Québec City, Quebec G1K 7P4, Canada.
3: Department of Surgery, Center for Anatomical Science and Education, St. Louis University School of Medicine, St. Louis, Missouri 63104.
4: Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona 85724-5050, and.
5: Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0810.
6: Department of Pharmacological and Physiological Science, St. Louis University School of Medicine, St. Louis, Missouri 63104, salvemd@slu.edu.

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