Published in Proc Natl Acad Sci U S A on August 01, 2011
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Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors. J Physiol (2009) 1.19
Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family. J Gen Physiol (2007) 1.16
A putative extracellular salt bridge at the subunit interface contributes to the ion channel function of the ATP-gated P2X2 receptor. J Biol Chem (2010) 1.09
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Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells. Cell Mol Neurobiol (2010) 0.85
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Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes. Am J Physiol Heart Circ Physiol (2010) 1.81
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Vesicular ATP is the predominant cause of intercellular calcium waves in astrocytes. J Gen Physiol (2007) 1.43
ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Res (2011) 1.38
Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors. J Neurosci (2012) 1.37
TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release. J Neurosci (2013) 1.36
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Patch-clamp coordinated spectroscopy shows P2X2 receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels. Proc Natl Acad Sci U S A (2008) 1.28
Bulk loading of calcium indicator dyes to study astrocyte physiology: key limitations and improvements using morphological maps. J Neurosci (2011) 1.22
Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy. Proc Natl Acad Sci U S A (2007) 1.21
Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family. J Gen Physiol (2007) 1.16
Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics. J Biol Chem (2004) 1.16
Tracking transmitter-gated P2X cation channel activation in vitro and in vivo. Nat Methods (2007) 1.11
Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters. Neuron Glia Biol (2010) 1.09
Time-resolved measurement of state-specific P2X2 ion channel cytosolic gating motions. J Neurosci (2004) 1.09
Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopy. J Biol Chem (2008) 1.08
Control of P2X(2) channel permeability by the cytosolic domain. J Gen Physiol (2002) 1.08
Regulation of P2X2 receptors by the neuronal calcium sensor VILIP1. Sci Signal (2008) 1.07
Glycine transporter dimers: evidence for occurrence in the plasma membrane. J Biol Chem (2008) 1.07
P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin. J Gen Physiol (2010) 1.07
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Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry. Cell Calcium (2009) 1.06
The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. Eur J Immunol (2009) 1.04
chi-Conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model. J Biol Chem (2007) 1.04
Tunable calcium current through TRPV1 receptor channels. J Biol Chem (2008) 1.03
Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor. Proc Natl Acad Sci U S A (2012) 1.03
ATP-gated ion channels mediate adaptation to elevated sound levels. Proc Natl Acad Sci U S A (2013) 1.02
Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor. J Neurosci (2004) 1.02
Genetically encoded calcium indicators and astrocyte calcium microdomains. Neuroscientist (2012) 1.01
High-resolution picture of a venom gland transcriptome: case study with the marine snail Conus consors. Toxicon (2011) 1.00
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Cloning and characterization of two novel zebrafish P2X receptor subunits. Biochem Biophys Res Commun (2002) 0.96
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Chemical synthesis of MT1 and MT7 muscarinic toxins: critical role of Arg-34 in their interaction with M1 muscarinic receptor. Mol Pharmacol (2003) 0.93
Large-scale discovery of conopeptides and conoproteins in the injectable venom of a fish-hunting cone snail using a combined proteomic and transcriptomic approach. J Proteomics (2012) 0.93
Comparative proteomic study of the venom of the piscivorous cone snail Conus consors. J Proteomics (2009) 0.93
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Measuring near plasma membrane and global intracellular calcium dynamics in astrocytes. J Vis Exp (2009) 0.91
Recruitment of glycosyl hydrolase proteins in a cone snail venomous arsenal: further insights into biomolecular features of Conus venoms. Mar Drugs (2012) 0.89
Neuronal P2X2 receptors are mobile ATP sensors that explore the plasma membrane when activated. J Neurosci (2011) 0.88
Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Mol Cell Proteomics (2013) 0.88
Imaging P2X4 receptor lateral mobility in microglia: regulation by calcium and p38 MAPK. J Biol Chem (2012) 0.87
Towards an integrated venomics approach for accelerated conopeptide discovery. Toxicon (2012) 0.86
Systematic interrogation of the Conus marmoreus venom duct transcriptome with ConoSorter reveals 158 novel conotoxins and 13 new gene superfamilies. BMC Genomics (2013) 0.86
Unravelling the complex venom landscapes of lethal Australian funnel-web spiders (Hexathelidae: Atracinae) using LC-MALDI-TOF mass spectrometry. J Proteomics (2013) 0.85
Proteomics to identify proteins interacting with P2X2 ligand-gated cation channels. J Vis Exp (2009) 0.84
Calcium-dependent decrease in the single-channel conductance of TRPV1. Pflugers Arch (2011) 0.82
MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors. Biochemistry (2013) 0.80
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Structure of the O-glycosylated conopeptide CcTx from Conus consors venom. Chemistry (2012) 0.79
Efficient binding of 4/7 α-conotoxins to nicotinic α4β2 receptors is prevented by Arg185 and Pro195 in the α4 subunit. Mol Pharmacol (2012) 0.77
Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response. Nucl Med Commun (2017) 0.75
ATP-gated P2X channels. Curr Biol (2004) 0.75
Venomics in medicinal chemistry. Future Med Chem (2014) 0.75
Conotoxin Φ-MiXXVIIA from the new superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angew Chem Int Ed Engl (2017) 0.75