Published in J Cell Sci on April 23, 2015
Multiple Roles of the Small GTPase Rab7. Cells (2016) 0.87
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Analysis of Signaling Endosome Composition and Dynamics Using SILAC in Embryonic Stem Cell-Derived Neurons. Mol Cell Proteomics (2015) 0.80
Arf-like GTPase Arl8: Moving from the periphery to the center of lysosomal biology. Cell Logist (2015) 0.78
A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin. Traffic (2016) 0.77
The Arf-like GTPase Arl8b is essential for three-dimensional invasive growth of prostate cancer in vitro and xenograft formation and growth in vivo. Oncotarget (2016) 0.77
The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol (2017) 0.75
Membrane Tethering Complexes in the Endosomal System. Front Cell Dev Biol (2016) 0.75
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Identification of the switch in early-to-late endosome transition. Cell (2010) 3.86
New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. J Cell Biol (2000) 3.69
ARF family G proteins and their regulators: roles in membrane transport, development and disease. Nat Rev Mol Cell Biol (2011) 3.38
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The CORVET tethering complex interacts with the yeast Rab5 homolog Vps21 and is involved in endo-lysosomal biogenesis. Dev Cell (2007) 2.44
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Membrane fusion: five lipids, four SNAREs, three chaperones, two nucleotides, and a Rab, all dancing in a ring on yeast vacuoles. Annu Rev Cell Dev Biol (2010) 2.13
Rab7 regulates late endocytic trafficking downstream of multivesicular body biogenesis and cargo sequestration. J Biol Chem (2009) 2.11
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Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L. J Cell Sci (2013) 1.79
Human Vam6p promotes lysosome clustering and fusion in vivo. J Cell Biol (2001) 1.75
An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility. J Cell Sci (2006) 1.71
MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling. Mol Biol Cell (2009) 1.67
Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex. Proc Natl Acad Sci U S A (2012) 1.66
A role for EHD4 in the regulation of early endosomal transport. Traffic (2008) 1.64
Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. Mol Biol Cell (2003) 1.58
Rubicon controls endosome maturation as a Rab7 effector. Proc Natl Acad Sci U S A (2010) 1.55
Defined subunit arrangement and rab interactions are required for functionality of the HOPS tethering complex. Traffic (2010) 1.53
HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly. Mol Biol Cell (2010) 1.48
The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17. Mol Biol Cell (2014) 1.46
Multisubunit tethering complexes and their role in membrane fusion. Curr Biol (2010) 1.46
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Arl8 and SKIP act together to link lysosomes to kinesin-1. Dev Cell (2011) 1.37
Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila. Mol Biol Cell (2014) 1.27
The major role of the Rab Ypt7p in vacuole fusion is supporting HOPS membrane association. J Biol Chem (2009) 1.27
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Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b. Immunity (2011) 1.24
The full-of-bacteria gene is required for phagosome maturation during immune defense in Drosophila. J Cell Biol (2011) 1.12
Impaired stimulation of p38α-MAPK/Vps41-HOPS by LPS from pathogenic Coxiella burnetii prevents trafficking to microbicidal phagolysosomes. Cell Host Microbe (2012) 1.02
The zebrafish mutant vps18 as a model for vesicle-traffic related hypopigmentation diseases. Pigment Cell Res (2006) 1.01
Diversity in structure and function of tethering complexes: evidence for different mechanisms in vesicular transport regulation. Curr Protein Pept Sci (2008) 1.01
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The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. Traffic (2012) 0.98
Structural basis for kinesin-1:cargo recognition. Science (2013) 0.97
The C. elegans LC3 acts downstream of GABARAP to degrade autophagosomes by interacting with the HOPS subunit VPS39. Dev Cell (2013) 0.96
Lysosomal membrane protein composition, acidic pH and sterol content are regulated via a light-dependent pathway in metazoan cells. Traffic (2011) 0.93
Functional analysis of VPS41-mediated neuroprotection in Caenorhabditis elegans and mammalian models of Parkinson's disease. J Neurosci (2012) 0.92
Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. Mol Biol Cell (2013) 0.92
Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway. Dev Cell (2012) 0.90
Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans. Mol Biol Cell (2013) 0.88
RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking. Sci Rep (2014) 0.84
Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1. Mol Biol Cell (2014) 0.82
Metazoan cell biology of the HOPS tethering complex. Cell Logist (2011) 0.81