Published in J Dent Res on April 27, 2015
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell (1997) 13.53
Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nat Genet (1994) 5.19
Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech Dev (2000) 3.90
Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev (1998) 3.49
Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation. Cell (1997) 3.08
Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell (1993) 3.00
The cutting-edge of mammalian development; how the embryo makes teeth. Nat Rev Genet (2004) 2.89
Signalling networks regulating dental development. Mech Dev (1997) 2.73
Mechanisms of ectodermal organogenesis. Dev Biol (2003) 2.55
Msx1 controls inductive signaling in mammalian tooth morphogenesis. Development (1996) 2.42
Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development (1993) 2.39
FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development (1998) 2.26
Transformation of tooth type induced by inhibition of BMP signaling. Science (1998) 2.16
An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol (2007) 2.03
Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice. Development (1999) 2.03
Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis. Dev Dyn (2000) 1.93
FGF10 maintains stem cell compartment in developing mouse incisors. Development (2002) 1.84
The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development (1998) 1.77
Modulation of Fgf3 dosage in mouse and men mirrors evolution of mammalian dentition. Proc Natl Acad Sci U S A (2009) 1.76
Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science (2009) 1.73
The genetic control of early tooth development. Crit Rev Oral Biol Med (1997) 1.61
Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development (2004) 1.58
BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development. Development (2000) 1.40
Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol (2004) 1.32
Conservation of early odontogenic signaling pathways in Aves. Proc Natl Acad Sci U S A (2000) 1.31
Tissue interactions in embryonic mouse tooth germs. II. The inductive role of the dental papilla. J Embryol Exp Morphol (1970) 1.23
Signaling networks regulating tooth organogenesis and regeneration, and the specification of dental mesenchymal and epithelial cell lineages. Cold Spring Harb Perspect Biol (2012) 1.14
Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. J Dent Res (2005) 1.09
Phenotypic changes in dentition of Runx2 homozygote-null mutant mice. J Histochem Cytochem (2004) 1.08
FGF signaling is necessary for the specification of the odontogenic mesenchyme. Dev Biol (2001) 1.07
Molecular patterning of the mammalian dentition. Semin Cell Dev Biol (2013) 1.05
Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (2013) 1.04
Tissue interactions in embryonic mouse tooth germs. I. Reorganization of the dental epithelium during tooth-germ reconstruction. J Embryol Exp Morphol (1970) 0.99
Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field. Dev Biol (2011) 0.94
Control of tooth morphogenesis by Runx2. Crit Rev Eukaryot Gene Expr (2006) 0.79