Published in Brain Sci on April 30, 2015
Preterm Erythropoietin Neuroprotection Trial (PENUT Trial) (PENUT) | NCT01378273
Darbe Administration in Newborns Undergoing Cooling for Encephalopathy (DANCE) | NCT01471015
Identification of Pathways in Liver Repair Potentially Targeted by Secretory Proteins from Human Mesenchymal Stem Cells. Int J Mol Sci (2016) 0.76
Dimethylsulfoniopropionate Promotes Process Outgrowth in Neural Cells and Exerts Protective Effects against Tropodithietic Acid. Mar Drugs (2016) 0.75
Growth factor therapy sequesters inflammation in affording neuroprotection in cerebrovascular diseases. Expert Rev Neurother (2016) 0.75
Enhanced neuroprotective efficacy of bone marrow mesenchymal stem cells co-overexpressing BDNF and VEGF in a rat model of cardiac arrest-induced global cerebral ischemia. Cell Death Dis (2017) 0.75
Systemic Inflammation during the First Postnatal Month and the Risk of Attention Deficit Hyperactivity Disorder Characteristics among 10 year-old Children Born Extremely Preterm. J Neuroimmune Pharmacol (2017) 0.75
Recombinant human erythropoietin in the treatment of acute ischemic stroke. Stroke (2009) 5.28
Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A (2000) 5.20
VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest (2000) 4.36
Pathophysiological consequences of VEGF-induced vascular permeability. Nature (2005) 4.08
Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature (1997) 4.01
Erythropoietin therapy for acute stroke is both safe and beneficial. Mol Med (2002) 3.87
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci U S A (2001) 3.80
The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr Rev (1999) 3.54
A potential role for erythropoietin in focal permanent cerebral ischemia in mice. J Cereb Blood Flow Metab (1999) 3.25
Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov (2011) 2.65
Intravenous brain-derived neurotrophic factor enhances poststroke sensorimotor recovery and stimulates neurogenesis. Stroke (2007) 2.54
The neurotrophin receptor p75(NTR): novel functions and implications for diseases of the nervous system. Nat Neurosci (2002) 2.53
BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion. J Cell Biol (2002) 2.40
Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemia. J Cereb Blood Flow Metab (2002) 2.22
Can erythropoietin be used to prevent brain damage in cerebral malaria? Trends Parasitol (2008) 2.19
The insulin-like growth factor system and its pleiotropic functions in brain. Endocr Rev (2005) 2.19
Enhanced oligodendrogenesis and recovery of neurological function by erythropoietin after neonatal hypoxic/ischemic brain injury. Stroke (2010) 2.18
VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain. J Clin Invest (1999) 2.08
VEGF and flt. Expression time kinetics in rat brain infarct. Stroke (1996) 2.06
Regulation of apoptosis by insulin-like growth factor (IGF)-I. Cytokine Growth Factor Rev (2006) 1.71
New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Mol Cell Neurosci (2009) 1.69
Erythropoietin improved neurologic outcomes in newborns with hypoxic-ischemic encephalopathy. Pediatrics (2009) 1.62
Regulation of erythropoietin production. New insights into molecular mechanisms of oxygen homeostasis. Hematol Oncol Clin North Am (1994) 1.58
Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke. Dev Neurosci (2007) 1.58
Postnatal erythropoietin treatment mitigates neural cell loss after systemic prenatal hypoxic-ischemic injury. J Neurosurg Pediatr (2010) 1.57
Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia. Stroke (2000) 1.55
Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model. Neurobiol Dis (2003) 1.53
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J (2005) 1.40
A critical threshold of rehabilitation involving brain-derived neurotrophic factor is required for poststroke recovery. Neurorehabil Neural Repair (2011) 1.39
Pharmacokinetics of high-dose recombinant erythropoietin in plasma and brain of neonatal rats. Pediatr Res (2007) 1.30
Erythropoietin improves functional and histological outcome in neonatal stroke. Pediatr Res (2005) 1.27
Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats. J Cereb Blood Flow Metab (1997) 1.27
Erythropoietin sustains cognitive function and brain volume after neonatal stroke. Dev Neurosci (2009) 1.26
Vascular endothelial growth factors (VEGFs) and stroke. Cell Mol Life Sci (2013) 1.26
Human recombinant erythropoietin in asphyxia neonatorum: pilot trial. Pediatrics (2010) 1.26
Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF-1 and GDNF. J Neurochem (2003) 1.25
Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly. Am J Med (2004) 1.21
MRI identification of white matter reorganization enhanced by erythropoietin treatment in a rat model of focal ischemia. Stroke (2009) 1.19
Erythropoietin protects the in vitro blood-brain barrier against VEGF-induced permeability. Eur J Neurosci (2003) 1.17
Arteriogenesis in hypoperfused rat brain. J Cereb Blood Flow Metab (2003) 1.17
Insulin-like growth factor-1 reduces postischemic white matter injury in fetal sheep. J Cereb Blood Flow Metab (2001) 1.12
Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat. Acta Neuropathol (2001) 1.11
Erythropoietin for neonatal brain injury: opportunity and challenge. Int J Dev Neurosci (2011) 1.08
Serum brain-derived neurotrophic factor and vascular endothelial growth factor levels are associated with risk of stroke and vascular brain injury: Framingham Study. Stroke (2013) 1.07
The growth factor progranulin attenuates neuronal injury induced by cerebral ischemia-reperfusion through the suppression of neutrophil recruitment. J Neuroinflammation (2013) 1.07
Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischemic injury in fetal lambs. J Clin Invest (1996) 1.06
Mesenchymal stem cell transplantation attenuates brain injury after neonatal stroke. Stroke (2013) 1.04
Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat. Metab Brain Dis (1997) 1.04
Erythropoietin in combination of tissue plasminogen activator exacerbates brain hemorrhage when treatment is initiated 6 hours after stroke. Stroke (2010) 1.03
Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke. Proc Natl Acad Sci U S A (2012) 1.02
Rapid alterations of BDNF protein levels in the rat brain after focal ischemia: evidence for increased synthesis and anterograde axonal transport. Exp Neurol (1998) 1.02
Post-ischemic administration of heparin-binding epidermal growth factor-like growth factor (HB-EGF) reduces infarct size and modifies neurogenesis after focal cerebral ischemia in the rat. J Cereb Blood Flow Metab (2004) 1.00
Erythropoietin increases neurogenesis and oligodendrogliosis of subventricular zone precursor cells after neonatal stroke. Stroke (2013) 0.98
Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum. PLoS One (2013) 0.97
Brain-derived neurotrophic factor administration mediated oligodendrocyte differentiation and myelin formation in subcortical ischemic stroke. Stroke (2014) 0.97
Progranulin deficiency promotes post-ischemic blood-brain barrier disruption. J Neurosci (2013) 0.96
Erythropoietin signaling promotes oligodendrocyte development following prenatal systemic hypoxic-ischemic brain injury. Pediatr Res (2013) 0.91
The Effects of Antecedent Exercise on Motor Function Recovery and Brain-derived Neurotrophic Factor Expression after Focal Cerebral Ischemia in Rats. J Phys Ther Sci (2013) 0.90
Exercise-induced insulin-like growth factor I system concentrations after training in women. Med Sci Sports Exerc (2013) 0.89
Endogenous erythropoietin from astrocyte protects the oligodendrocyte precursor cell against hypoxic and reoxygenation injury. J Neurosci Res (2011) 0.88
Delayed VEGF treatment enhances angiogenesis and recovery after neonatal focal rodent stroke. Transl Stroke Res (2013) 0.88
Creating a neurogenic environment: the role of BDNF and FGF2. Mol Cell Neurosci (2007) 0.87
Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study. BMC Neurol (2013) 0.86
Elevating maternal insulin-like growth factor-I in mice and rats alters the pattern of fetal growth by removing maternal constraint. J Endocrinol (1992) 0.85
Ischemic neurons activate astrocytes to disrupt endothelial barrier via increasing VEGF expression. J Neurochem (2013) 0.85
Aerobic exercises enhance cognitive functions and brain derived neurotrophic factor in ischemic stroke patients. NeuroRehabilitation (2014) 0.85
Neuroprotection by GDNF in the ischemic brain. Growth Factors (2012) 0.84
Involvement of BDNF and NGF in the mechanism of neuroprotective effect of human recombinant erythropoietin nanoforms. Bull Exp Biol Med (2013) 0.83
Insulin-like growth factor-1 as a prognostic marker in patients with acute ischemic stroke. PLoS One (2014) 0.82
The neuroprotective effect of recombinant human erythropoietin via an antiapoptotic mechanism on hypoxic-ischemic brain injury in neonatal rats. Korean J Pediatr (2010) 0.82
Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury. F1000Res (2014) 0.81
VEGF ameliorates cognitive impairment in in vivo and in vitro ischemia via improving neuronal viability and function. Neuromolecular Med (2013) 0.80
Physical exercise promotes recovery of neurological function after ischemic stroke in rats. Int J Mol Sci (2014) 0.80
The neuroprotective effects of intramuscular insulin-like growth factor-I treatment in brain ischemic rats. PLoS One (2013) 0.79
Changes in serum growth factors in stroke rehabilitation patients and their relation to hemiparesis improvement. J Stroke Cerebrovasc Dis (2014) 0.78
Effect of treadmill exercise on 5-HT, 5-HT1A receptor and brain derived neurophic factor in rats after permanent middle cerebral artery occlusion. Neurol Sci (2013) 0.78
Forebrain specific heparin-binding epidermal growth factor-like growth factor knockout mice show exacerbated ischemia and reperfusion injury. Neuroscience (2011) 0.78
Post-ischemic continuous infusion of erythropoeitin enhances recovery of lost memory function after global cerebral ischemia in the rat. BMC Neurosci (2013) 0.77
Protective effects of VEGF treatment on focal cerebral ischemia in rats. Mol Med Rep (2012) 0.77
Insulin-like growth factor-1 secreted by brain microvascular endothelial cells attenuates neuron injury upon ischemia. FEBS J (2013) 0.77
Insulin-like growth factors and cerebral ischemia. Ann N Y Acad Sci (1993) 0.77
NMDA-mediated and self-induced bdnf exon IV transcriptions are differentially regulated in cultured cortical neurons. Neurochem Int (2009) 0.77
Neuroprotective role of nerve growth factor in hypoxic-ischemic brain injury. Brain Sci (2013) 0.76
Granulocyte colony-stimulating factor regulates JNK pathway to alleviate damage after cerebral ischemia reperfusion. Chin Med J (Engl) (2013) 0.76
[Erythropoietin and neonatal brain injury]. Zhonghua Er Ke Za Zhi (2011) 0.76
Expression of neuronal-NOS in developing basal forebrain cholinergic neurons: regulation by NGF. Neurochem Res (1996) 0.76
Effects of a single dose of erythropoietin on motor function and cognition after focal brain ischemia in adult rats. Prague Med Rep (2014) 0.75
Therapeutic potential of hepatocyte growth factor against cerebral ischemia (Review). Exp Ther Med (2014) 0.75