Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism.

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🔗 View Article (PMID 25986747)

Published in Neurotherapeutics on July 01, 2015

Authors

Peter E Davis1, Jurriaan M Peters, Darcy A Krueger, Mustafa Sahin

Author Affiliations

1: Department of Neurology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, 02115, MA, USA, Peter.Davis@childrens.harvard.edu.

Associated clinical trials:

Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC) (TSC) | NCT01289912

A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures (EXIST-3) | NCT01713946

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC) | NCT01070316

Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex (RAPIT) | NCT01730209

Rapalogues for Autism Phenotype in TSC: A Feasibility Study (RAPT) | NCT01929642

Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC) | NCT01780441

Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC | NCT01767779

A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis (TRON) | NCT01954693

Long-term Follow-up for Growth and Development of Pediatric Patients From CRAD001M2301 (EXIST-LT) | NCT02338609

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP) | NCT02098759

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