Resistance to Antiangiogenic Therapy Is Associated with an Immunosuppressive Tumor Microenvironment in Metastatic Renal Cell Carcinoma.

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Published in Cancer Immunol Res on May 26, 2015

Authors

Xian-De Liu1, Anh Hoang1, Lijun Zhou1, Sarathi Kalra1, Alper Yetil1, Mianen Sun1, Zhiyong Ding2, Xuesong Zhang1, Shanshan Bai1, Peter German1, Pheroze Tamboli1, Priya Rao1, Jose A Karam1, Christopher Wood1, Surena Matin1, Amado Zurita1, Axel Bex3, Arjan W Griffioen4, Jianjun Gao1, Padmanee Sharma1, Nizar Tannir1, Kanishka Sircar1, Eric Jonasch5

Author Affiliations

1: Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
2: Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
3: Department of Urology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
4: Department of Medical Oncology, VU University Medical Center, Amsterdam, the Netherlands.
5: Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ejonasch@mdanderson.org.

Associated clinical trials:

Neoadjuvant Clinical Trial to Evaluate the Efficacy of Bevacizumab for Renal Cell Carcinoma | NCT00113217

Sorafenib Tosylate With or Without Recombinant Interferon Alfa-2b in Treating Patients With Metastatic Kidney Cancer | NCT00126594

Pre-Surgical Sutent in Renal Cell Carcinoma (RCC) | NCT00715442

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